Zu "K10170" wurden 58 Artikel gefunden!
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R-848
Artikelnummer: Cay14806-10
R-848 is an immune response modifier that mimics the pathogen-associated molecular patterns that activate immune cells through Toll-like receptor 7 (TLR7) and TLR8. It demonstrates potent anti-tumor and anti-viral properties and has been used to study the innate immune response to viral infections. At 1 µg/ml,...
| Schlagworte: | Resiquimod, S 28463, 4-amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol |
| Anwendung: | Immune response modifier, TLR7 / TLR8 PAMP |
| CAS | 144875-48-9 |
| MW: | 314.4 D |
ab 73,00 €
CU-CPT8m
Artikelnummer: Cay25349-1
CU-CPT8m is an antagonist of toll-like receptor 8 (TLR8, Kd = 220 nM, IC50 = 67 nM in a reporter assay). It is selective for TLR8 over a panel of all other human TLRs when used at a concentration of 1 µM. CU-CPT8m (1 µM) inhibits increases in TNF-alpha and IL-8 mRNA expression induced by the TLR8 agonist R-848...
| Schlagworte: | 7-(3-methylphenyl)-pyrazolo[1,5-a]pyrimidine-3-carboxamide |
| Anwendung: | TLR8 antagonist |
| CAS | 125079-83-6 |
| MW: | 252.3 D |
ab 49,00 €
Resiquimod
Artikelnummer: LKT-R183731.10
Toll-like receptor 7/8 agonist
| Schlagworte: | R-848, R848, S28463, alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol.,... |
| Anwendung: | Immune response modifier, TLR7 / TLR8 PAMP |
| CAS | 144875-48-9 |
| MW: | 314.39 D |
ab 83,00 €
Anti-Toll-Like Receptor 8 (Clone 44C143)
Artikelnummer: Cay13592-1
The toll-like receptors (TLRs) in mammals comprise a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and an interleukin-1 (IL-1) receptor motif in the cytoplasmic domain. Like their counterparts in Drosophila, TLRs signal through adaptor...
| Schlagworte: | TLR8 |
| Anwendung: | WB, FC (intracellular, cell surface), IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
480,00 €
Anti-TLR8, clone 44C143
Artikelnummer: 200-301-I30
Anti-TLR8 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with Anti-TLR8 from human and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with Anti-TLR8 from other sources has not been determined. Protein function: Key component of...
| Schlagworte: | Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8 |
| Anwendung: | FC, IHC, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
860,00 €
Motolimod
Artikelnummer: Cay22952-5
Motolimod is an agonist of toll-like receptor 8 (TLR8). It increases the production of TNF-alpha and IL-12 in human peripheral blood mononuclear cells (PBMCs, EC50s = 140 and 120 nM, respectively), monocytes, and myeloid dendritic cells. Motolimod also increases IFN-gamma production in natural killer (NK) cells and...
| Schlagworte: | VTX-2337, 2-amino-N,N-dipropyl-8-[4-(1-pyrrolidinylcarbonyl)phenyl]-3H-1-benzazepine-4-carboxamide |
| Anwendung: | Toll-like receptor 8 (TLR8) agonist |
| CAS | 926927-61-9 |
| MW: | 458.6 D |
ab 50,00 €
Anti-TLR8 (Toll Like Receptor-8)
Artikelnummer: 600-401-958
Protein function: Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory...
| Schlagworte: | Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
848,00 €
Anti-TLR8
Artikelnummer: NSJ-R30824
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. It has also been designated as CD288 (cluster of differentiation 288). The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental...
| Schlagworte: | Anti-Toll-like receptor 8, TLR8 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat |
790,00 €
Anti-TLR8
Artikelnummer: NSJ-R32333
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Toll-like receptor 8 is a protein that in humans is encoded by the TLR8 gene. TLR8 has also been designated as CD288 (cluster of differentiation 288).The TLR8 gene is mapped to Xp22.3-p22.2 by Chuang and Ulevitch (2000) and Du et al. (2000). The protein encoded...
| Schlagworte: | Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8, TLR8 Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Anti-TLR8
Artikelnummer: E-AB-13839.120
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated...
| Schlagworte: | Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8, TLR8 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-TLR8
Artikelnummer: NSJ-F44380-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. TLR8 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize...
| Schlagworte: | Anti-Tlr8, Anti-CD288, Anti-Toll-like receptor 8, TLR8 Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-TLR8
Artikelnummer: E-AB-10873.120
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated...
| Schlagworte: | Anti-TLR8, Anti-CD288, Anti-Toll-like receptor 8, TLR8 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €