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Zu "K09680" wurden 53 Artikel gefunden!
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Artikelnummer: Cay31002-1
Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK, IC50s = 70, 92, and 25 nM for PanK1beta, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A (CoA, Cay-16147, Cay-21499, Cay-21722). It binds to the ATP-PanK3 complex with an apparent...
| Schlagworte: | PanK Inhibitor, PANKi, 2,4-dimethyl-N-[3-(methylthio)phenyl]-pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidine-3-propanamide |
| Anwendung: | Reversible pantothenate kinase inhibitor (PANKi) |
| CAS | 902614-04-4 |
| MW: | 391.5 D |
ab 52,00 €
Artikelnummer: ATA-HPA008440.100
Protein function: May be the master regulator of the CoA biosynthesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Schlagworte: | Anti-PANK2, Anti-hPanK2, Anti-C20orf48, EC=2.7.1.33, Anti-Pantothenic acid kinase 2, Anti-Pantothenate kinase 2,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Artikelnummer: ATA-HPA062358.100
Protein function: Plays a role in the physiological regulation of coenzyme A (CoA) levels. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
| Schlagworte: | Anti-PANK3, Anti-hPanK3, Anti-Pantothenate kinase 3, Anti-Pantothenic acid kinase 3 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
Artikelnummer: Cay37309-10
PZ-2891 is a modulator of pantothenate kinase (PanK). It selectively inhibits PanK1beta, PanK2, and PanK3 (IC50s = 40.2, 0.7, and 1.3 nM, respectively) in the absence of acetyl-CoA over 468 other kinases and a panel of 72 receptors and ion channels at 10 µM. PZ-2891 (2.5 µM) reverses acetyl-CoA-induced inhibition of...
| Schlagworte: | Pantazine 2891, 6-[4-[2-[4-(1-methylethyl)phenyl]acetyl]-1-piperazinyl]-3-pyridazinecarbonitrile |
| Anwendung: | Pantothenate kinase modulator |
| CAS | 2170608-82-7 |
| MW: | 349.4 D |
ab 122,00 €
Artikelnummer: TGM-T37248-10mg
Description: Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK, IC50s = 70, 92, and 25 nM for PanK1beta, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM...
| Anwendung: | Pantothenate Kinase inhibitor |
| CAS | 902614-04-4 |
| MW: | 391.49 D |
ab 115,00 €
Artikelnummer: TGM-T5185-100mg
Description: PZ-2891 is an orally bioavailable, brain-penetrant pantothenate kinase (PANK) modulator, with an IC50 of 1.3 nM for hPANK3. Target: Others. Smiles: CC(C)c1ccc(CC(=O)N2CCN(CC2)c2ccc(nn2)C#N)cc1. References: Lalit, Kumar, Sharma, et al. A therapeutic approach to pantothenate kinase associated...
| Anwendung: | Pantothenate kinase modulator |
| CAS | 2170608-82-7 |
| MW: | 349.43 D |
ab 33,00 €
NEU
Artikelnummer: G-PACO11066.100
PANK3 Antibody is a premium polyclonal that offers outstanding performance and reliability for demanding research applications. Rigorously validated for ELISA, WB, this antibody ensures consistent, reproducible results across multiple experimental platforms. Demonstrates excellent reactivity with Human, Mouse, Rat...
| Schlagworte: | Anti-PANK3, Anti-Pantothenate kinase 3, Anti-Pantothenic acid kinase 3 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
1.124,00 €
Artikelnummer: ABS-PP-12396-L.100
Protein function: Plays a role in the physiological regulation of the intracellular CoA concentration. [The UniProt Consortium]
| Schlagworte: | Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, Recombinant Human PANK1 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 11 kD |
ab 115,00 €
Artikelnummer: ABS-PP-12452-L.100
Protein function: Plays a role in the physiological regulation of coenzyme A (CoA) levels. [The UniProt Consortium]
| Schlagworte: | Pantothenate kinase 3, hPanK3, Pantothenic acid kinase 3, Recombinant Human PANK3 Protein |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 13.5 kD |
ab 115,00 €
Artikelnummer: ABS-PQ-826-L.100
Protein function: May be the master regulator of the CoA biosynthesis. [The UniProt Consortium]
| Schlagworte: | Pantothenate kinase 2, mitochondrial, hPanK2, Pantothenic acid kinase 2) [Cleaved into: Pantothenate kinase 2,... |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 63.5 kD |
ab 295,00 €
Artikelnummer: ABS-PQ-818-L.100
Protein function: Plays a role in the physiological regulation of the intracellular CoA concentration. [The UniProt Consortium]
| Schlagworte: | Pantothenate kinase 1, hPanK, hPanK1, Pantothenic acid kinase 1, Recombinant Human PANK1 Protein |
| Exprimiert in: | human cells |
| Ursprungsart: | human |
| MW: | 58 kD |
ab 295,00 €
Artikelnummer: CSB-PA125299XA01OFG.100
Make to order. Production time: 70-80 business days. Deliverables: 1. 200 µg antigen (used as positive control), 2. 1 ml pre-immune serum (used as negative control) , 3. Rabbit polyclonal antibody, antigen affinity purified. Quality Guarantee: 1. Antibody purity > 90% confirmed by SDS-PAGE, 2. Antibody titer > 1:...
| Schlagworte: | EC=2.7.1.33, Anti-P0529B09.16, Anti-Os06g0207000, Anti-Pantothenate kinase 1, Anti-Pantothenic acid kinase 1, Os06g0207000... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | Oryza sativa subsp. japonica (Rice) |
ab 1.529,00 €