Zu "K09680" wurden 55 Artikel gefunden!
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Pantothenate Kinase Inhibitor
Artikelnummer: Cay31002-1
Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK, IC50s = 70, 92, and 25 nM for PanK1beta, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A (CoA, Cay-16147, Cay-21499, Cay-21722). It binds to the ATP-PanK3 complex with an apparent...
| Schlagworte: | PanK Inhibitor, PANKi, 2,4-dimethyl-N-[3-(methylthio)phenyl]-pyrido[2',3':3,4]pyrazolo[1,5-a]pyrimidine-3-propanamide |
| Anwendung: | Reversible pantothenate kinase inhibitor (PANKi) |
| CAS | 902614-04-4 |
| MW: | 391.5 D |
ab 54,00 €
Anti-PANK2
Artikelnummer: ATA-HPA008440.100
Protein function: May be the master regulator of the CoA biosynthesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Schlagworte: | Anti-PANK2, Anti-hPanK2, Anti-C20orf48, EC=2.7.1.33, Anti-Pantothenic acid kinase 2, Anti-Pantothenate kinase 2,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
491,00 €
Anti-PANK3
Artikelnummer: ATA-HPA062358.100
Protein function: Plays a role in the physiological regulation of coenzyme A (CoA) levels. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 100% and to rat: 100%
| Schlagworte: | Anti-PANK3, Anti-hPanK3, Anti-Pantothenate kinase 3, Anti-Pantothenic acid kinase 3 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
PZ-2891
Artikelnummer: Cay37309-10
PZ-2891 is a modulator of pantothenate kinase (PanK). It selectively inhibits PanK1beta, PanK2, and PanK3 (IC50s = 40.2, 0.7, and 1.3 nM, respectively) in the absence of acetyl-CoA over 468 other kinases and a panel of 72 receptors and ion channels at 10 µM. PZ-2891 (2.5 µM) reverses acetyl-CoA-induced inhibition of...
| Schlagworte: | Pantazine 2891, 6-[4-[2-[4-(1-methylethyl)phenyl]acetyl]-1-piperazinyl]-3-pyridazinecarbonitrile |
| Anwendung: | Pantothenate kinase modulator |
| CAS | 2170608-82-7 |
| MW: | 349.4 D |
ab 126,00 €
Pantothenate Kinase Inhibitor
Artikelnummer: TGM-T37248-10mg
Description: Pantothenate Kinase Inhibitor (PANKi) is a reversible inhibitor of pantothenate kinase (PanK, IC50s = 70, 92, and 25 nM for PanK1beta, PanK2, and PanK3, respectively), the rate-limiting enzyme in the synthesis of coenzyme A .1It binds to the ATP-PanK3 complex with an apparent binding constant of 300 nM...
| Anwendung: | Pantothenate Kinase inhibitor |
| CAS | 902614-04-4 |
| MW: | 391.49 D |
ab 115,00 €
PZ-2891
Artikelnummer: TGM-T5185-100mg
Description: PZ-2891 is an orally bioavailable, brain-penetrant pantothenate kinase (PANK) modulator, with an IC50 of 1.3 nM for hPANK3. Target: Others. Smiles: CC(C)c1ccc(CC(=O)N2CCN(CC2)c2ccc(nn2)C#N)cc1. References: Lalit, Kumar, Sharma, et al. A therapeutic approach to pantothenate kinase associated...
| Anwendung: | Pantothenate kinase modulator |
| CAS | 2170608-82-7 |
| MW: | 349.43 D |
ab 33,00 €
Anti-PANK2
Artikelnummer: ATA-HPA008440.25
Protein function: May be the master regulator of the CoA biosynthesis. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Schlagworte: | Anti-PANK2, Anti-hPanK2, Anti-C20orf48, EC=2.7.1.33, Anti-Pantothenic acid kinase 2, Anti-Pantothenate kinase 2,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
241,00 €
Anti-PANK2
Artikelnummer: E-AB-92074.120
This gene encodes a protein belonging to the pantothenate kinase family and is the only member of that family to be expressed in mitochondria. Pantothenate kinase is a key regulatory enzyme in the biosynthesis of coenzyme A (CoA) in bacteria and mammalian cells. It catalyzes the first committed step in the universal...
| Schlagworte: | PANK2, C20orf48, PANK2 Polyclonal Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 243,00 €
PANK3 Antibody
Artikelnummer: G-PACO11066.100
PANK3 Antibody is a premium polyclonal that offers outstanding performance and reliability for demanding research applications. Rigorously validated for ELISA, WB, this antibody ensures consistent, reproducible results across multiple experimental platforms. Demonstrates excellent reactivity with Human, Mouse, Rat...
| Schlagworte: | Anti-PANK3, Anti-Pantothenate kinase 3, Anti-Pantothenic acid kinase 3 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
1.124,00 €
PANK2, Human pantothenate kinase 2, Real Time PCR Primer Set
Artikelnummer: VHPS-6619
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | PANK2, hPanK2, C20orf48, EC=2.7.1.33, Pantothenic acid kinase 2, Pantothenate kinase 2, mitochondrial |
| Anwendung: | RNA quantification |
45,00 €
PANK3, Human pantothenate kinase 3, Real Time PCR Primer Set
Artikelnummer: VHPS-6620
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | PANK3, hPanK3, EC=2.7.1.33, Pantothenate kinase 3, Pantothenic acid kinase 3 |
| Anwendung: | RNA quantification |
45,00 €
PANK4, Human pantothenate kinase 4, Real Time PCR Primer Set
Artikelnummer: VHPS-6621
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | PANK4, hPanK4, EC=2.7.1.33, Pantothenate kinase 4, Pantothenic acid kinase 4 |
| Anwendung: | RNA quantification |
45,00 €