Zu "K09580" wurden 52 Artikel gefunden!
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16F16
Artikelnummer: Cay17770-1
16F16 is a protein disulfide isomerase (PDI) inhibitor. It inhibits PDI reductase activity in an enzyme assay when used at concentrations ranging from 1 to 100 µg/ml. 16F16 reduces PC12 cell apoptosis induced by the misfolded huntingtin protein HTTQ103. It suppresses PDI-dependent mitochondrial outer membrane...
| Schlagworte: | 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-methyl-1H-pyrido[3,4-b]indole-1-carboxylic acid, methyl ester |
| Anwendung: | PDI inhibitor |
| CAS | 922507-80-0 |
| MW: | 320.8 D |
ab 53,00 €
Anti-Pdi1, clone 38H8
Artikelnummer: ARG10746.100
Protein function: Protein disulfide isomerase of ER lumen required for formation of disulfide bonds in secretory and cell-surface proteins and which unscrambles non-native disulfide bonds. Forms a complex with MNL1 to process unfolded protein-bound Man8GlcNAc2 oligosaccharides to Man7GlcNAc2, promoting degradation...
| Schlagworte: | Anti-PDI, Anti-MFP1, Anti-PDI1, Anti-YCL313, Anti-YCL043C, EC=5.3.4.1, Anti-Protein disulfide-isomerase,... |
| Anwendung: | WB, ICC, IF, IHC (frozen) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | yeast |
624,00 €
Anti-P4HB
Artikelnummer: ARG55126.100
Protein function: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell,...
| Schlagworte: | Anti-PDI, Anti-p55, Anti-P4HB, Anti-ERBA2L, EC=5.3.4.1, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase... |
| Anwendung: | WB, ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 436,00 €
Anti-P4HB/PDI
Artikelnummer: A304-790A
Protein function: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell,...
| Schlagworte: | Anti-p55, Anti-PDI, Anti-P4HB, Anti-ERBA2L, EC=5.3.4.1, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Human Protein Disulfide Isomerase ELISA Kit
Artikelnummer: G-HUFI02717.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Mouse Protein Disulfide Isomerase ELISA Kit
Artikelnummer: G-MOFI01036.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Anti-PDI
Artikelnummer: 100-401-G29
Anti-PDI Antibody was prepared from monospecific antiserum by delipidation and defibrination. A BLAST analysis was used to suggest cross-reactivity with PDI from Human, Mouse, Rat, Dog, Hamster, Monkey, Guinea pig, Bovine, Sheep, Pig, and Xenopus based on 100% homology with the immunizing sequence. Cross-reactivity...
| Schlagworte: | Anti-PDI, Anti-P4hb, Anti-Pdia1, EC=5.3.4.1, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase subunit beta,... |
| Anwendung: | IHC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, dog, hamster, monkey, guinea pig, bovine, sheep, swine, Xenopus |
684,00 €
CCF-642
Artikelnummer: Cay27054-1
CCF-642 is an inhibitor of protein disulfide isomerase (PDI). It inhibits the reducing capacity of PDI when used at a concentration of 1 µM. It inhibits proliferation in ten multiple myeloma cell lines with IC50 values of less than 1 µM. It is cytotoxic to primary cells isolated from patients with refractory myeloma...
| Schlagworte: | 3-(4-methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone |
| Anwendung: | PDI inhibitor |
| CAS | 346640-08-2 |
| MW: | 378.4 D |
ab 43,00 €
Human P4HB ELISA Kit
Artikelnummer: ARG82415.96
Protein function: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell,...
| Schlagworte: | PDI, p55, P4HB, ERBA2L, EC=5.3.4.1, Protein disulfide-isomerase, Prolyl 4-hydroxylase subunit beta, Cellular thyroid... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
1.048,00 €
LOC14
Artikelnummer: Cay17766-10
LOC14 is an inhibitor of protein disulfide isomerase (PDI, Kd = 62 nM). It inhibits PDI chaperone activity in an insulin aggregation assay when used at a concentration of 75 µM. LOC14 reduces PC12 cell death induced by the misfolded huntingtin protein mHTTQ103 (EC50 = 500 nM). It reduces medium spiny neuron (MSN)...
| Schlagworte: | 2-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-1,2-benzisothiazol-3(2H)-one |
| Anwendung: | PDI inhibitor |
| CAS | 877963-94-5 |
| MW: | 317.4 D |
ab 125,00 €
PACMA 31
Artikelnummer: Cay32812-10
PACMA 31 is an irreversible inhibitor of protein disulfide isomerase (PDI, IC50 = 10 µM), an endoplasmic reticulum chaperone protein that catalyzes disulfide bond breakage, formation, and rearrangement. It inhibits PDI chaperone activity in a concentration- and time-dependent manner in an insulin aggregation assay...
| Schlagworte: | N-(2,4-dimethoxyphenyl)-N-(1-oxo-2-propyn-1-yl)-2-(2-thienyl)glycyl-glycine, ethyl ester |
| Anwendung: | PDI inhibitor |
| CAS | 1401089-31-3 |
| MW: | 430.5 D |
ab 84,00 €
Anti-P4HB
Artikelnummer: ATA-HPA018884.100
Protein function: This multifunctional protein catalyzes the formation, breakage and rearrangement of disulfide bonds. At the cell surface, seems to act as a reductase that cleaves disulfide bonds of proteins attached to the cell. May therefore cause structural modifications of exofacial proteins. Inside the cell,...
| Schlagworte: | Anti-p55, Anti-PDI, Anti-P4HB, Anti-ERBA2L, EC=5.3.4.1, Anti-Protein disulfide-isomerase, Anti-Prolyl 4-hydroxylase... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 300,00 €