Zu "K09107" wurden 31 Artikel gefunden!
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Anti-SREBP-2
Artikelnummer: Cay10007663-1
SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. SREBP-2 regulates cholesterol synthesis by activating the transcription...
| Schlagworte: | Anti-BHLHD2, Anti-bHLHd2, Anti-SREBP-2 {ECO:0000303|PubMed:15461802}, Anti-Class D basic helix-loop-helix protein 2,... |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
456,00 €
Fatostatin (hydrobromide)
Artikelnummer: Cay13562-5
Sterol regulatory element binding proteins (SREBPs) are transcription factors that have pivotal roles in lipogenesis and fat metabolism. The activation of SREBPs requires escort to the Golgi by SREBP cleavage-activating protein (SCAP) followed by proteolytic release of SREBP from the Golgi. Fatostatin is an...
| Schlagworte: | 125B11, 4-[4-(4-methylphenyl)-2-thiazolyl]-2-propyl-pyridine, hydrobromide |
| Anwendung: | SREBP activation inhibitor |
| CAS | 298197-04-3 |
| MW: | 375.3 D |
ab 92,00 €
Betulin
Artikelnummer: Cay11041-250
Sterol regulatory element binding protein 2 (SREBP-2) regulates cholesterol synthesis by activating the transcription of genes for HMG-CoA reductase and other enzymes of the cholesterol synthetic pathway. When cellular sterol levels are high, SREBP is bound by SCAP and Insig to ER membranes as a glycosylated...
| Schlagworte: | NSC 4644, Trochol, lup-20(29)-ene-3beta,28-diol |
| Anwendung: | Cholesterol control |
| CAS | 473-98-3 |
| MW: | 442.7 D |
ab 43,00 €
Anti-SREBP2
Artikelnummer: A303-125A-T
Protein function: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL...
| Schlagworte: | Anti-BHLHD2, Anti-SREBF2 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-SREBP-2 - Biotinylated
Artikelnummer: Cay22728-50
Cayman's SREBP-2 Polyclonal Antibody - Biotinylated detects both precursor and active forms of the protein in tissues and cells such as liver, brown fat, testis, HepG2 cells, and human fibroblast. The apparent molecular weight on SDS-PAGE may be higher than the calculated molecular weight (about 126 kDa) due to...
| Schlagworte: | Anti-BHLHD2, Anti-bHLHd2, Anti-SREBP-2 {ECO:0000303|PubMed:15461802}, Anti-Class D basic helix-loop-helix protein 2,... |
| Anwendung: | IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
488,00 €
Betulin
Artikelnummer: AG-CN2-0476-M250
White solid. Soluble in DMSO, DMF or ethanol. Specific SREBPs (sterol regulatory element-binding proteins) inhibitor. Inhibits ER-Golgi translocation of SREBPs through binding to SCAP in an INSIG-dependent manner, Improves hyperlipidemia and insulin resistance and reduces atherosclerotic plaques. Lowers cholesterol...
| Schlagworte: | Betulinol, Trochol, NSC 4644 |
| Anwendung: | Specific SREBP inhibitor |
| CAS | 473-98-3 |
| MW: | 442,7 D |
ab 55,00 €
Anti-SREBP2 Monoclonal Antibody (Clone: SREBP2/1579)
Artikelnummer: ABE-36-3213-20
The low density lipoprotein (LDL) receptor mediates the endocytic uptake of cholesterol-carrying lipoproteins, thereby controlling cholesterol levels in cells and plasma. Transcription of the LDL receptor gene is controlled by a ten base pair sequence in the 5' flanking region, designated sterol regulatory element 1...
| Schlagworte: | Anti-BHLHD2, Anti-SREBP2 Monoclonal Antibody (Clone: SREBP2/1579) |
| Anwendung: | ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
Anti-SREBP-2
Artikelnummer: ARG56539.250
Protein function: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as the cholesterol and to a lesser degree the fatty acid synthesis pathway. Binds the sterol regulatory element 1 (SRE-1) (5'-ATCACCCCAC-3') found in the flanking region of the LDRL...
| Schlagworte: | Anti-SREBF2, Anti-BHLHD2 |
| Anwendung: | ICC, IF, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
656,00 €
Human SREBF2 / Sterol regulatory element-binding protein...
Artikelnummer: G-HUFI01122.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Anti-ST3gal6
Artikelnummer: 600-401-EV2
Anti-ST3gal6 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with ST3gal6 from other sources has not been determined. Protein function: Transcriptional activator required for lipid homeostasis. Regulates transcription of the LDL receptor gene as well as...
| Schlagworte: | Anti-SREBF2, Anti-BHLHD2 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
684,00 €
Betulin
Artikelnummer: LKT-B1977.1
Pentacyclic triterpene found in various plant sources.
| Schlagworte: | Lup-20(29)-ene-3beta,28-diol |
| Anwendung: | Pentacyclic triterpene found in various plant sources |
| CAS | 473-98-3 |
| MW: | 442.72 D |
ab 121,00 €
Anti-SREBP2
Artikelnummer: NSJ-F40837-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SREBPs, including SREBP-1a, SREBP-1c, and SREBP-2, constitute a family of basic helix-loop-helix (bHLH) transcription factors that play a critical role in lipid homeostasis by regulating genes involved in cholesterol and fatty acid metabolism. Each SREBP consists of three...
| Schlagworte: | Anti-BHLHD2, Anti-SREBF2, SREBP2 Antibody |
| Anwendung: | IHC, IF, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 326,00 €