Zu "K09095" wurden 59 Artikel gefunden!
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Anti-HIF2-alpha Recombinant Monoclonal
Artikelnummer: A700-003
Protein function: Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of...
| Schlagworte: | Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-BHLHE73, Anti-bHLHe73, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-HIF-1-alpha-like... |
| Anwendung: | WB, IP, IHC, ICC, ICC-IF, ChIP-Seq |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
172,00 €
ab 137,60 €
HIF-2alpha Translation Inhibitor 76
Artikelnummer: Cay42446-10
HIF-2alpha translation inhibitor 76 is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha) translation. It inhibits constitutive gene expression in a hypoxia-response element (HRE) reporter assay using VHL-deficient 786-O renal cell carcinoma (RCC) cells (IC50 = 5 µM). HIF-2alpha translation inhibitor 76...
| Schlagworte: | Hypoxia-Inducible Factor-2alpha Translation Inhibitor 76,... |
| Anwendung: | HIF-2alpha translation inhibitor |
| CAS | 882268-69-1 |
| MW: | 287.32 D |
ab 95,00 €
HIF-2alpha Antagonist 2
Artikelnummer: Cay16971-5
HIF-2alpha antagonist 2 is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha) PAS-B domain heterodimerization. It binds to the HIF-2alpha PAS-B domain (Kd = 81 nM) to inhibit heterodimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT) PAS-B domain in cell-free assays when used at...
| Schlagworte: | N-(3-chloro-5-fluorophenyl)-4-nitro-2,1,3-benzoxadiazol-5-amine |
| Anwendung: | EPAS-1 PAS-B domain heterodimerization inhibitor |
| CAS | 1422955-31-4 |
| MW: | 308.7 D |
ab 57,00 €
Belzutifan
Artikelnummer: Cay39652-1
Belzutifan is an inhibitor of hypoxia-inducible factor-2alpha (HIF-2alpha). It inhibits HIF-2alpha heterodimerization with the aryl hydrocarbon receptor nuclear translocator (ARNT) PAS-B domain in a cell-free assay (Ki = 23 nM), activation of HIF-2alpha in a reporter assay using 786-O renal cell carcinoma cells...
| Schlagworte: | MK-6482, PT2977,... |
| Anwendung: | HIF-2alpha inhibitor |
| CAS | 1672668-24-4 |
| MW: | 383.3 D |
ab 49,00 €
Belzutifan
Artikelnummer: TGM-T16679-1mg
Description: Belzutifan (MK-6482) is a potential treatment for clear cell renal cell carcinoma (ccRCC). Belzutifan is an orally active and selective HIF-2alpha inhibitor (IC50: 9 nM). Belzutifan , as a second-generation HIF-2alpha inhibitor, increases potency and improves pharmacokinetic profile. Target: HIF....
| Schlagworte: | MK-6482, PT2977 |
| Anwendung: | Targets hypoxia-inducible factor 2 alpha (HIF2A, EPAS1) |
| CAS | 1672668-24-4 |
| MW: | 383.34 D |
ab 60,00 €
Human EPAS1 / HIF-2-alpha ELISA Kit
Artikelnummer: G-HUFI01715.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-HO-1, clone 1F12-A6
Artikelnummer: 200-301-F47
Anti-HO-1 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with HO-1 from Human, Mouse, Bovine, Canine, Guinea pig, Hamster, Monkey, Pig, Rabbit, and Rat based on 100% homology with the immunizing sequence. Does not cross-react with HO-2. Cross-reactivity with...
| Schlagworte: | Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-BHLHE73, Anti-bHLHe73, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-HIF-1-alpha-like... |
| Anwendung: | ELISA, IHC, IFM, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, bovine, dog, guinea pig, hamster, monkey, swine, rabbit, rat |
752,00 €
Anti-HIF2a
Artikelnummer: NSJ-R30298
0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-2 alpha is also designated EPAS1 whose gene is mapped to 2p21-p16. The predicted mouse protein is 88% identical to human. The human gene contains 15 exons and spans at least 120 kb. The positions of the introns within the genomic region encoding the...
| Schlagworte: | Anti-Hif2a, Anti-Epas1, Anti-EPAS-1, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-Hypoxia-inducible factor 2-alpha,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Human HIF-2 alpha (Hypoxia Inducible Factor 2 Alpha)...
Artikelnummer: G-HUES03331.96
ELISA Type: Sandwich. Sensitivity: 0.094ng/mL. Range: 0.156--10ng/mL. Protein function: Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT, heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters....
| Schlagworte: | HLF, EPAS1, EPAS-1, bHLHe73, BHLHE73, HIF2-alpha, HIF-2-alpha, HIF-1-alpha-like factor, Member of PAS protein 2, PAS... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | human |
708,00 €
Mouse HIF-2 alpha (Hypoxia Inducible Factor 2 Alpha)...
Artikelnummer: G-MOES01264.96
ELISA Type: Sandwich. Sensitivity: 0.188ng/mL . Range: 0.313--20ng/mL . Protein function: Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT, heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters...
| Schlagworte: | HRF, HLF, mHLF, Epas1, Hif2a, EPAS-1, HIF2-alpha, HIF-2-alpha, HIF-related factor, HIF-1-alpha-like factor,... |
| Anwendung: | Sandwich ELISA |
| Spezies-Reaktivität: | mouse |
708,00 €
Anti-HIF-2 alpha
Artikelnummer: NSJ-RQ5882
0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-2 alpha is also designated EPAS1 whose gene is mapped to 2p21-p16. The predicted mouse protein is 88% identical to human EPAS1. The human EPAS1 gene contains 15 exons and spans at least 120 kb. The positions of the introns within the genomic region encoding...
| Schlagworte: | Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-bHLHe73, Anti-BHLHE73, Anti-HIF2-alpha, Anti-HIF-2-alpha, Anti-HIF-1-alpha-like... |
| Anwendung: | WB, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-EPAS1 / HIF-2 alpha
Artikelnummer: ARG43450.100
Protein function: Transcription factor involved in the induction of oxygen regulated genes. Heterodimerizes with ARNT, heterodimer binds to core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems...
| Schlagworte: | Anti-HLF, Anti-HLF, Anti-EPAS1, Anti-EPAS-1, Anti-EPAS-1, Anti-BHLHE73, Anti-bHLHe73, Anti-bHLHe73, Anti-HIF2-alpha,... |
| Anwendung: | FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €