Zu "K09093" wurden 133 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
FICZ
Artikelnummer: BPS-84088-1
FICZ is a potent AhR (aryl hydrocarbon receptor) agonist. Aryl hydrocarbon receptor (AhR) is a ligand-dependent nuclear receptor that functions as a transcription factor. It can follow a canonical signaling pathway where binding of ligands to the cytosolic AhR induces the formation of a complex that translocates to...
| Schlagworte: | AHR, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Cellular assays |
| CAS | 172922-91-7 |
| MW: | 284.31 D |
ab 292,00 €
Tapinarof
Artikelnummer: BPS-84089-1
Tapinarof, also known as WBI-1001, is a natural AhR (aryl hydrocarbon receptor) agonist. Aryl hydrocarbon receptor (AhR) is a ligand-dependent nuclear receptor that functions as a transcription factor. It can follow a canonical signaling pathway where binding of ligands to the cytosolic AhR induces the formation of...
| Schlagworte: | AHR, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Cellular assays |
| CAS | 79338-84-4 |
| MW: | 254.32 D |
ab 270,00 €
MeBIO
Artikelnummer: BPS-84090-1
MeBIO is a potent AhR (aryl hydrocarbon receptor) agonist. Aryl hydrocarbon receptor (AhR) is a ligand-dependent nuclear receptor that functions as a transcription factor. It can follow a canonical signaling pathway where binding of ligands to the cytosolic AhR induces the formation of a complex that translocates to...
| Schlagworte: | AHR, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Cellular assays |
| CAS | 667463-95-8 |
| MW: | 370.20 D |
ab 335,00 €
GNF351
Artikelnummer: BPS-84091-1
GNF351 is a potent AhR (aryl hydrocarbon receptor) antagonist. Aryl hydrocarbon receptor (AhR) is a ligand-dependent nuclear receptor that functions as a transcription factor. It can follow a canonical signaling pathway where binding of ligands to the cytosolic AhR induces the formation of a complex that...
| Schlagworte: | AHR, Aryl hydrocarbon receptor, Class E basic helix-loop-helix protein 76 |
| Anwendung: | Cellular assays |
| CAS | 1227634-69-6 |
| MW: | 411.50 D |
ab 367,00 €
L-Kynurenine
Artikelnummer: Cay11305-50
L-Kynurenine is an active metabolite of tryptophan (Cay-29600, Cay-31210). It is formed from tryptophan via tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO). L-Kynurenine binds to the aryl hydrocarbon receptor (AhR, Kd = ~4 µM) and increases the activity of ethoxyresorufin-O-deethylase (EROD) in...
| Schlagworte: | 3-anthraniloyl-Alanine, alphaS,2-diamino-gamma-oxo-benzenebutanoic acid |
| Anwendung: | AHR ligand |
| CAS | 2922-83-0 |
| MW: | 208.2 D |
ab 70,00 €
2,3,7,8-Tetrachlorodibenzo-p-dioxin
Artikelnummer: Cay38392-1
2,3,7,8-Tetrachlorodibenzo-p-dioxin is a toxicant and an agonist of the aryl hydrocarbon receptor (AhR, ED50 = 0.2 nmol/kg in a reporter assay using chicken embryos). It also induces AhR ubiquitination and degradation in Hepa-1c1c7 hepatic cells when used at a concentration of 1 nM. Oral administration of...
| Schlagworte: | 2,3,7,8-Tetrachlorodibenzo-1,4-dioxin, 2,3,7,8-Tetrachlorodibenzodioxin, TCDBD, TCDD,... |
| Anwendung: | AhR agonist, toxicant |
| CAS | 1746-01-6 |
| MW: | 322 D |
421,00 €
alpha-Naphthoflavone
Artikelnummer: Cay16924-1
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that promotes the expression of phase I and II xenobiotic chemical metabolizing enzyme genes, including the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1A2. alpha-Naphthoflavone is a flavone that modulates xenobiotic metabolism at...
| Schlagworte: | 7,8-Benzoflavone, NSC 407011, 2-phenyl-4H-naphtho[1,2-b]pyran-4-one |
| Anwendung: | AhR expression modulator |
| CAS | 604-59-1 |
| MW: | 272.3 D |
ab 45,00 €
StemRegenin 1
Artikelnummer: Cay10625-1
Extending the pluripotency of hematopoietic stem cells (HSC) is of key importance to the application of stem cell therapies in a variety of diseases. Loss of the expression of the cell surface proteins CD34 and CD133 is one marker of HSC differentiation and thus often monitored in assays to test potential compounds...
| Schlagworte: | SR1, 4-[2-[[2-benzo[b]thien-3-yl-9-(1-methylethyl)-9H-purin-6-yl]amino]ethyl]-phenol |
| Anwendung: | Aryl hydrocarbon receptor inhibitor |
| CAS | 1227633-49-9 |
| MW: | 429.5 D |
ab 55,00 €
L-Kynurenine-d4
Artikelnummer: Cay36307-1
L-Kynurenine-d4 is intended for use as an internal standard for the quantification of kynurenine by GC- or LC-MS. L-Kynurenine is an active metabolite of tryptophan (Cay-29600, Cay-31210). It is formed from tryptophan via tryptophan 2,3-dioxygenase (TDO) or indoleamine 2,3-dioxygenase (IDO). L-Kynurenine binds to...
| Schlagworte: | 3-anthraniloyl-Alanine-d4, L-KYN-d4, (S)-2-amino-4-(2-aminophenyl-3,5-d2)-4-oxobutanoic-3,3-d2 acid |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, AHR ligand |
| CAS | 2672568-86-2 |
| MW: | 212.2 D |
ab 91,00 €
![6-Formylindolo[3,2-b]carbazole](https://www.biomol.com/media/image/67/54/71/Cay19529-1_200x200.png "6-Formylindolo[3,2-b]carbazole")
6-Formylindolo[3,2-b]carbazole
Artikelnummer: Cay19529-1
6-Formylindolo[3,2-b]carbazole (FICZ) is a degradation product of tryptophan upon exposure to visible light that activates the aryl hydrocarbon receptor (AhR, Kd = 70 pM). This endogenous AhR ligand is also a good substrate for cytochromes P450 (CYP) 1A1, 1A2, and 1B1 (Kis = 15.4, 3.9, and 13.3 µM, respectively)....
| Schlagworte: | FICZ, 5,11-dihydro-indolo[3,2-b]carbazole-6-carboxaldehyde |
| Anwendung: | AhR agonist |
| CAS | 172922-91-7 |
| MW: | 284.3 D |
ab 97,00 €
Formononetin
Artikelnummer: Cay17558-5
Formononetin is an isoflavonoid phytoestrogenic compound found in soy-based foods and is the precursor of daidzein (Cay-10005166). It acts as an agonist of the aryl hydrocarbon receptor with an EC50 value of 0.13 µM. Formononetin has been reported to possess antitumor and antiviral activity.Formal Name:...
| Schlagworte: | Biochanin B, NSC 93360, 7-hydroxy-3-(4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | Aryl hydrocarbon receptor agonist |
| CAS | 485-72-3 |
| MW: | 268.3 D |
ab 51,00 €
CH 223191
Artikelnummer: Cay16154-5
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that up-regulates many xenobiotic metabolizing enzymes, particularly in response to planar aromatic hydrocarbons. CH 223191 is a potent and specific antagonist of AhR that blocks activation by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD,...
| Schlagworte: | 1-methyl-N-[2-methyl-4-[2-(2-methylphenyl)diazenyl]phenyl]-1H-pyrazole-5-carboxamide |
| Anwendung: | Aryl hydrocarbon receptor (AhR) antagonist |
| CAS | 301326-22-7 |
| MW: | 333.4 D |
ab 107,00 €