Zu "K08960" wurden 35 Artikel gefunden!
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PF-4800567
Artikelnummer: Cay19171-5
PF-4800567 is a selective inhibitor of casein kinase 1epsilon (CK1epsilon, IC50 = 32 nM) with greater than 20-fold selectivity over CK1delta. It blocks CK1epsilon-mediated PER3 nuclear localization and PER2 degradation, both of which are proteins important for maintaining circadian rhythms in cells. PF-4800567 has...
| Schlagworte: | 3-[(3-chlorophenoxy)methyl]-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | CSNK1E inhibitor |
| CAS | 1188296-52-7 |
| MW: | 359.8 D |
ab 50,00 €
Anti-CKI epsilon
Artikelnummer: A302-135A
Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1,...
| Schlagworte: | Anti-CKIe, Anti-CSNK1E, EC=2.7.11.1, Anti-CKI-epsilon, Anti-Casein kinase I isoform epsilon |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 164,00 €
Anti-Casein Kinase 1, epsilon (CK1epsilon), clone 4D7
Artikelnummer: 0172-100
| Schlagworte: | Anti-CKI-epsilon, Anti-CSNK1E, EC=2.7.11.1 |
| Anwendung: | WB, ELISA |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat dog |
383,00 €
PF-670462 (hydrochloride)
Artikelnummer: Cay14588-50
The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-670462 is a potent inhibitor of the CK1 isoforms CK1epsilon and CK1delta (IC50 = 7.7 and 14 nM, respectively). It less effectively inhibits a wide variety of related...
| Schlagworte: | 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine, dihydrochloride |
| Anwendung: | CK1 epsilon and CK1 delta inhibitor |
| CAS | 950912-80-8 |
| MW: | 410.3 D |
ab 222,00 €
Anti-CSNK1E, C-terminal
Artikelnummer: ARG64445.100
Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines...
| Schlagworte: | Anti-CKIe, Anti-CSNK1E, Anti-CKI-epsilon, EC=2.7.11.1, Anti-Casein kinase I isoform epsilon |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Anti-CK1 epsilon
Artikelnummer: ARG65671.100
Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1. Central component of the circadian clock. In balance with PP1, determines...
| Schlagworte: | Anti-CKIe, Anti-CSNK1E, Anti-CKI-epsilon, EC=2.7.11.1, Anti-Casein kinase I isoform epsilon |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
CK1 epsilon, GST-Tag
Artikelnummer: BPS-79349
Full length recombinant human CK1epsilon, also known as CSNK1E, HCKIE, MGC10398, and CK1E. Genbank Accession NM_001894 N-terminal GST-tag, expressed in Sf9 cells via a baculovirus expression system. MW = 72kDa.
| Schlagworte: | CKIe, CSNK1E, CKI-epsilon, Casein kinase I isoform epsilon, |
| Anwendung: | Kinase assays, WB |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 72 kD |
862,00 €
Anti-CSNK1E
Artikelnummer: NSJ-R34962-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Casein kinase 1 epsilon Protein function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large...
| Schlagworte: | Anti-CKIe, Anti-CSNK1E, Anti-CKI-epsilon, Anti-Casein kinase I isoform epsilon, CSNK1E Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
Anti-CSNK1E
Artikelnummer: E-AB-10950.120
The protein encoded by this gene is a serine/threonine protein kinase and a member of the casein kinase I protein family, whose members have been implicated in the control of cytoplasmic and nuclear processes, including DNA replication and repair. The encoded protein is found in the cytoplasm as a monomer and can...
| Schlagworte: | Anti-CKIe, Anti-CSNK1E, EC=2.7.11.1, Anti-CKI-epsilon, Anti-Casein kinase I isoform epsilon, CSNK1E Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
TA-01
Artikelnummer: Cay24667-10
TA-01 is a derivative of the p38 MAPK inhibitor SB 203580 (Cay-13067, Cay-13344) and an inducer of cardiomyocyte differentiation. It is cardiomyogenic at concentrations less than 5 µM, increasing expression of the cardiomyocyte marker NKX2-5 by 2.2-fold and decreasing expression of mesoderm markers and the...
| Schlagworte: | 4-[2-(2,6-difluorophenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine |
| Anwendung: | CK1epsilon / CK1Delta inhibitor |
| CAS | 1784751-18-3 |
| MW: | 351.3 D |
ab 43,00 €
IC261
Artikelnummer: Cay17260-10
IC261 is a reversible, ATP-competitive inhibitor of casein kinase 1 (CK1) that inhibits CK1delta and CK1? (IC50 = ~1 µM for both), as well as CK1alpha (IC50 = 16 µM). It is at least 100-fold less effective against PKA, p34cdc2, and p55fyn. IC 261, at 1 µM, inhibits cytokinesis in primary mouse embryo fibroblasts....
| Schlagworte: | SU5607, 1,3-dihydro-3-[(2,4,6-trimethoxyphenyl)methylene]-2H-indol-2-one |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 186611-52-9 |
| MW: | 311.3 D |
ab 43,00 €
SR 3029
Artikelnummer: Cay27048-25
SR 3029 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 44 and 260 nM, respectively). It is selective for CK1delta and CK1epsilon over 438 kinases in a panel but also inhibits MYLK4, FLT3, Cdk4/cyclin D1, and MARK2 by greater than 90% at 10 µM. SR 3029 inhibits Cdk4/cyclin D1, Cdk4/cyclin...
| Schlagworte: | N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 1454585-06-8 |
| MW: | 480.5 D |
ab 115,00 €