Zu "K08959" wurden 48 Artikel gefunden!
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CK1-IN-1
Artikelnummer: TGM-T5393-100mg
Description: CK1-IN-1 (PUN51207) is a casein kinase 1 (CK1) inhibitor. CK1-IN-1 has IC50s of 15 nM, 16 nM, 73 nM for CK1delta, and CK1epsilon, p38sigma MAPK, respectively. Target: Casein Kinase, p38 MAPK. Smiles: Fc1ccc(cc1)-c1nc([nH]c1-c1ccncc1)-c1ccc2ccccc2c1F. References: Filip LACO,et al. 2,4,5-tri-substituted...
| Schlagworte: | PUN51207 |
| Anwendung: | CK1delta / CK1epsilon inhibitor |
| CAS | 1784751-20-7 |
| MW: | 383.39 D |
ab 42,00 €
LH846
Artikelnummer: TGM-T1877-10mg
Description: LH846 is a selective inhibitor of CK1delta with IC50 values of 290 nM for CK1delta, 1.3 µM for CK1epsilon, and 2.5 µM for CK1alpha, and exhibits no inhibitory activity at CK2. Target: Casein Kinase. Smiles: Cc1cc2sc(NC(=O)Cc3ccccc3)nc2cc1Cl. References: Lee JW, et al. Angew Chem Int Ed Engl. 2011 Nov...
| Schlagworte: | LH 846, LH-846 |
| Anwendung: | CSNK1D inhibitor |
| CAS | 639052-78-1 |
| MW: | 316.81 D |
ab 58,00 €
CK1-IN-1
Artikelnummer: Cay37313-10
CK1-IN-1 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 15 and 16 nM, respectively). It is selective for CK1delta and CK1epsilon over TGF-beta receptor type 1 (ALK5, IC50 = 151.8 nM) and TGF-beta receptor type 2 (TGFBR2) at 1 µM.Formal Name:...
| Schlagworte: | Casein Kinase 1 Inhibitor 1, CK1 Inhibitor 1, 4-[2-(1-fluoro-2-naphthalenyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-pyridine |
| Anwendung: | CK1delta / CK1epsilon inhibitor |
| CAS | 1784751-20-7 |
| MW: | 383.4 D |
ab 148,00 €
PF-670462
Artikelnummer: TGM-T3073-100mg
Description: PF-670462 is a potent (IC50 = 7.7 ± 2.2 nM) and selective (>30-fold with respect to 42 additional kinases) inhibitor of CK1epsilon in isolated enzyme preparations. Target: Casein Kinase. Smiles: Cl.Cl.Nc1nccc(n1)-c1c(ncn1C1CCCCC1)-c1ccc(F)cc1. References: Daniel I Perez, et al. Med Res Rev.2011,31(6):...
| Schlagworte: | PF670462 |
| Anwendung: | CK1 epsilon and CK1 delta inhibitor |
| CAS | 950912-80-8 |
| MW: | 410.32 D |
ab 42,00 €
SR-3029
Artikelnummer: TGM-T3972-10mg
Description: SR-3029 is a highly potent and specific inhibitor of CK1delta/CK1epsilon. Target: Casein Kinase. Smiles: Fc1cccc(c1)-n1cnc2c(NCc3nc4ccc(F)c(F)c4[nH]3)nc(nc12)N1CCOCC1. References: Rosenberg LH,et al. Therapeutic targeting of casein kinase 1delta in breast cancer. Sci Transl Med. 2015 Dec...
| Schlagworte: | SR3029 |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 1454585-06-8 |
| MW: | 480.45 D |
ab 31,00 €
Anti-CSNK1D
Artikelnummer: CSB-PA007359.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-CKId, Anti-HCKID, Anti-CSNK1D, Anti-CKI-delta, EC=2.7.11.1, EC=2.7.11.26, Anti-Tau-protein kinase CSNK1D, Anti-Casein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Anti-CSNK1D
Artikelnummer: CSB-PA193371.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CSNK1D. Antigen Species: Human
| Schlagworte: | Anti-CKId, Anti-HCKID, Anti-CSNK1D, Anti-CKI-delta, EC=2.7.11.1, EC=2.7.11.26, Anti-Tau-protein kinase CSNK1D, Anti-Casein... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-CSNK1D
Artikelnummer: CSB-PA595607.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: CSNK1D. Antigen Species: Human
| Schlagworte: | Anti-CKId, Anti-HCKID, Anti-CSNK1D, Anti-CKI-delta, EC=2.7.11.1, EC=2.7.11.26, Anti-Tau-protein kinase CSNK1D, Anti-Casein... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-CKI delta
Artikelnummer: A302-136A
Protein function: Essential serine/threonine-protein kinase that regulates diverse cellular growth and survival processes including Wnt signaling, DNA repair and circadian rhythms. It can phosphorylate a large number of proteins. Casein kinases are operationally defined by their preferential utilization of acidic...
| Schlagworte: | Anti-CKId, Anti-HCKID, Anti-CSNK1D, Anti-CKI-delta, EC=2.7.11.1, EC=2.7.11.26, Anti-Tau-protein kinase CSNK1D, Anti-Casein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 178,00 €
SR 3029
Artikelnummer: Cay27048-5
SR 3029 is an inhibitor of casein kinase 1delta (CK1delta) and CK1epsilon (IC50s = 44 and 260 nM, respectively). It is selective for CK1delta and CK1epsilon over 438 kinases in a panel but also inhibits MYLK4, FLT3, Cdk4/cyclin D1, and MARK2 by greater than 90% at 10 µM. SR 3029 inhibits Cdk4/cyclin D1, Cdk4/cyclin...
| Schlagworte: | N-[(6,7-difluoro-1H-benzimidazol-2-yl)methyl]-9-(3-fluorophenyl)-2-(4-morpholinyl)-9H-purin-6-amine |
| Anwendung: | Casein kinase 1 delta / epsilon inhibitor |
| CAS | 1454585-06-8 |
| MW: | 480.5 D |
ab 117,00 €
PF-670462 (hydrochloride)
Artikelnummer: Cay14588-10
The casein kinase 1 (CK1) family of kinases regulate diverse processes, particularly related to circadian rhythms and sensitivity to amphetamines. PF-670462 is a potent inhibitor of the CK1 isoforms CK1epsilon and CK1delta (IC50 = 7.7 and 14 nM, respectively). It less effectively inhibits a wide variety of related...
| Schlagworte: | 4-[1-cyclohexyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-2-pyrimidinamine, dihydrochloride |
| Anwendung: | CK1 epsilon and CK1 delta inhibitor |
| CAS | 950912-80-8 |
| MW: | 410.3 D |
ab 227,00 €
Epiblastin A
Artikelnummer: Cay22758-5
Epiblastin A is an ATP-competitive inhibitor of the casein kinase 1 (CK1) isoforms alpha, delta, and epsilon (IC50s = 8.9, 0.5, and 4.7 µM, respectively). It is selective for CK1alpha, CK1delta, and CK1epsilon at concentrations below 10 µM, however, it also inhibits BRSK1, EEF2K, EGFR, MNK-2, and RIPK2 (IC50s =...
| Schlagworte: | 6-(3-chlorophenyl)-2,4,7-pteridinetriamine |
| Anwendung: | CK1 alpha/delta/epsilon inhibitor |
| CAS | 16470-02-3 |
| MW: | 287.7 D |
ab 44,00 €