Zu "K08894" wurden 47 Artikel gefunden!
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BRK
Artikelnummer: BPS-40403
Human BRK, also known as PTK6 (GenBank Accession No. NM_005975), 2-451 (end), with N-terminal GST-tag, MW=80 kDa, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | BRK, PTK6, Breast tumor kinase, Protein-tyrosine kinase 6, Tyrosine-protein kinase BRK, |
| Anwendung: | Enzyme kinetics, screening inhibitors, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 80 kD |
536,00 €
Tilfrinib
Artikelnummer: Cay25647-5
Tilfrinib is an inhibitor of breast tumor kinase/protein tyrosine kinase 6 (BRK/PTK6, IC50 = 3.15 nM). It is selective for BRK/PTK6 over HER2 (IC50 = 1,300 nM). Tilfrinib inhibits the growth of MCF-7, HS-578/T, and BT-549 breast cancer cells in vitro (GI50s = 0.99, 1.02, and 1.58 µM, respectively).Formal Name:...
| Schlagworte: | 3-(9H-pyrido[2,3-b]indol-4-ylamino)-phenol |
| Anwendung: | BRK / PTK6 inhibitor |
| CAS | 1600515-49-8 |
| MW: | 275.3 D |
ab 68,00 €
Tilfrinib
Artikelnummer: TGM-T17098-5mg
Description: Tilfrinib is an effective and selective inhibitor of breast tumor kinase(Brk, IC50 = 3.15 nM) which displays anti-proliferative and anti-tumor activities. Target: BTK. Smiles: Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1. References: Mahmoud KA, et al. Discovery of 4-anilino alpha-carbolines as novel Brk...
| Anwendung: | BRK / PTK6 inhibitor |
| CAS | 1600515-49-8 |
| MW: | 275.3 D |
ab 37,00 €
Anti-Brk
Artikelnummer: ARG55789.100
Protein function: Non-receptor tyrosine-protein kinase implicated in the regulation of a variety of signaling pathways that control the differentiation and maintenance of normal epithelia, as well as tumor growth. Function seems to be context dependent and differ depending on cell type, as well as its intracellular...
| Schlagworte: | Anti-BRK, Anti-PTK6, EC=2.7.10.2, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-PTK6
Artikelnummer: E-AB-11011.120
The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase whicHuman, Mouseay function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially...
| Schlagworte: | Anti-BRK, Anti-PTK6, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK, PTK6... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-PTK6
Artikelnummer: ATA-HPA036070.100
Protein function: Non-receptor tyrosine-protein kinase implicated in the regulation of a variety of signaling pathways that control the differentiation and maintenance of normal epithelia, as well as tumor growth. Function seems to be context dependent and differ depending on cell type, as well as its intracellular...
| Schlagworte: | Anti-BRK, Anti-PTK6, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-PTK6
Artikelnummer: ATA-HPA036071.100
Protein function: Non-receptor tyrosine-protein kinase implicated in the regulation of a variety of signaling pathways that control the differentiation and maintenance of normal epithelia, as well as tumor growth. Function seems to be context dependent and differ depending on cell type, as well as its intracellular...
| Schlagworte: | Anti-BRK, Anti-PTK6, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
BRK Kinase Assay Kit
Artikelnummer: BPS-78841
The breast tumor kinase (BRK) Kinase Assay Kit is designed to measure BRK tyrosine kinase activity for screening and profiling applications using ADP-Glo(TM) as a detection reagent.
| Schlagworte: | BRK, PTK6, Breast tumor kinase, Protein-tyrosine kinase 6, Tyrosine-protein kinase BRK, |
| Anwendung: | Enzyme kinetics, small molecule inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
827,00 €
Human PTK6 (Protein Tyrosine Kinase 6) ELISA Kit
Artikelnummer: ELK-ELK4921.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PTK6. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PTK6. Next,...
| Schlagworte: | BRK, PTK6, Breast tumor kinase, Protein-tyrosine kinase 6, Tyrosine-protein kinase BRK |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Anti-Phospho-PTK6 (Y447)
Artikelnummer: CSB-PA040087.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-phospho-BRK, Anti-phospho-PTK6, Anti-phospho-Breast tumor kinase, Anti-phospho-Protein-tyrosine kinase 6,... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 126,00 €
Anti-PTK6
Artikelnummer: CSB-PA997274.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTK6. Antigen Species: Human
| Schlagworte: | Anti-BRK, Anti-PTK6, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK, Breast... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Anti-PTK6
Artikelnummer: CSB-PA142965.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: PTK6. Antigen Species: Human
| Schlagworte: | Anti-BRK, Anti-PTK6, Anti-Breast tumor kinase, Anti-Protein-tyrosine kinase 6, Anti-Tyrosine-protein kinase BRK, Breast... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 167,00 €