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Zu "K08893" wurden 44 Artikel gefunden!
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Artikelnummer: NSJ-FY13358
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. HCK antibody detects Hematopoietic cell kinase, a non-receptor tyrosine kinase encoded by the HCK gene on chromosome 20q11.21. HCK is a member of the Src family of kinases and is expressed predominantly in cells of the myeloid and B-lymphoid...
| Schlagworte: | Anti-HCK, Anti-p59Hck, Anti-p61Hck, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic cell kinase,... |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
790,00 €
Artikelnummer: Cay18168-1
A-419259 is an inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 µM). A-419259 inhibits growth of Philadelphia chromosome-positive (Ph+) K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 µM, respectively), but not Ph- TF-1 and HEL cells....
| Schlagworte: | RK-20449, 7-[trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine,... |
| Anwendung: | Src family kinase inhibitor |
| CAS | 1435934-25-0 |
| MW: | 592 D |
ab 67,00 €
Artikelnummer: Cay13198-10
The Src family of non-receptor tyrosine kinases regulate cell adhesion, growth, and differentiation through activation of multiple intracellular signaling pathways. Normally inactive, Src kinases are transiently activated during mitosis and constitutively activated by abnormal mutations. PP2 is a potent, reversible,...
| Schlagworte: | AGL 1879, 3-(4-chlorophenyl)-1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Anwendung: | Tyrosine kinase inhibitor |
| CAS | 172889-27-9 |
| MW: | 301.8 D |
ab 49,00 €
Artikelnummer: BPS-40440
Recombinant human HCK (230-497) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_002110.
| Schlagworte: | HCK, p61Hck, p59Hck, EC=2.7.10.2, p59-HCK/p60-HCK, Hemopoietic cell kinase, Hematopoietic cell kinase, Tyrosine-protein... |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 57 kD |
901,00 €
Artikelnummer: E-AB-14119.120
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil...
| Schlagworte: | Anti-HCK, Anti-p59Hck, Anti-p61Hck, EC=2.7.10.2, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Artikelnummer: Cay25605-5
A-419259 is an inhibitor of Src family kinases, including Src, LCK, Lyn, and Hck (IC50s = 9, 50 = 3,000 nM) and PKC (IC50 = >33 µM). A-419259 inhibits growth of Philadelphia chromosome-positive (Ph+) K-562 and Meg-01 myeloid leukemia cells (IC50s = 0.1-0.3 and 0.1 µM, respectively), but not Ph- TF-1 and HEL cells....
| Schlagworte: | RK-20449, 7-[trans-4-(4-methyl-1-piperazinyl)cyclohexyl]-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
| Anwendung: | Src family kinase inhibitor |
| CAS | 364042-47-7 |
| MW: | 482.6 D |
ab 122,00 €
Artikelnummer: ARG59607.100
Protein function: Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses, including neutrophil, monocyte, macrophage and mast cell functions, phagocytosis, cell survival and...
| Schlagworte: | Anti-HCK, Anti-p59Hck, Anti-p61Hck, EC=2.7.10.2, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Artikelnummer: ARG59625.100
Protein function: Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses, including neutrophil, monocyte, macrophage and mast cell functions, phagocytosis, cell survival and...
| Schlagworte: | Anti-HCK, Anti-p59Hck, Anti-p61Hck, EC=2.7.10.2, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
616,00 €
Artikelnummer: ATA-HPA063768.100
Protein function: Non-receptor tyrosine-protein kinase found in hematopoietic cells that transmits signals from cell surface receptors and plays an important role in the regulation of innate immune responses, including neutrophil, monocyte, macrophage and mast cell functions, phagocytosis, cell survival and...
| Schlagworte: | Anti-HCK, Anti-p61Hck, Anti-p59Hck, EC=2.7.10.2, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Artikelnummer: ELK-ELK5594.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HCK. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HCK. Next,...
| Schlagworte: | HCK, p59Hck, p61Hck, EC=2.7.10.2, p59-HCK/p60-HCK, Hemopoietic cell kinase, Hematopoietic cell kinase, Tyrosine-protein... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Artikelnummer: CSB-PA002872.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-HCK, Anti-p59Hck, Anti-p61Hck, EC=2.7.10.2, Anti-p59-HCK/p60-HCK, Anti-Hemopoietic cell kinase, Anti-Hematopoietic... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
Artikelnummer: CSB-PA033999.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits with...
| Schlagworte: | Anti-phospho-HCK, Anti-phospho-p59Hck, Anti-phospho-p61Hck, EC=2.7.10.2, Anti-phospho-p59-HCK/p60-HCK,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
340,00 €