Zu "K08886" wurden 59 Artikel gefunden!
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Human TNK2 (Tyrosine Kinase, Non Receptor 2) ELISA Kit
Artikelnummer: ELK-ELK3298.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TNK2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TNK2. Next,...
| Schlagworte: | ACK1, TNK2, ACK-1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
AIM 100
Artikelnummer: Cay29487-5
AIM 100 is an inhibitor of activated Cdc42 kinase 1/tyrosine non-receptor kinase 2 (ACK1/TNK2, IC50 = 21.58 nM). It is selective for ACK1/TNK2 over Abl1, BTK, LCK, and LYN (IC50s = 705.9, 871.7, 432.3, and 346.7 nM, respectively), as well as a panel of 25 additional kinases. AIM 100 (1 µM) inhibits EGF-induced...
| Schlagworte: | 5,6-diphenyl-N-[[(2S)-tetrahydro-2-furanyl]methyl]-furo[2,3-d]pyrimidin-4-amine |
| Anwendung: | ACK1/TNK2 inhibitor |
| CAS | 873305-35-2 |
| MW: | 371.4 D |
ab 125,00 €
ACK1, active human recombinant protein
Artikelnummer: BPS-40400
Active recombinant human Ack1 (GenBank Accession No. NM_005781), full length (a-a 110-476) with N-terminal GST tag, MW=68 kDa, expressed in Sf9 insect cell systems.
| Schlagworte: | ACK1, TNK2, ACK-1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2, |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 68 kD |
525,00 €
Human ACK1 / TNK2 ELISA Kit
Artikelnummer: G-HUFI02905.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
XMD16-5
Artikelnummer: Cay23353-1
XMD16-5 is an inhibitor of tyrosine kinase non-receptor 2 (TNK2, IC50 = 0.38 µM), which contains mutations in certain cancer cells. It also decreases viability of Ba/F3 cells expressing the oncogenic TNK2 D163E and R806Q mutant proteins (IC50s = 16 and 77 nM, respectively) without affecting viability of parental...
| Schlagworte: | 5,11-dihydro-2-[[4-(4-hydroxy-1-piperidinyl)phenyl]amino]-11-methyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one |
| Anwendung: | TNK2 inhibitor |
| CAS | 1345098-78-3 |
| MW: | 416.5 D |
ab 50,00 €
GNF-7
Artikelnummer: Cay19918-10
GNF-7 is a multi-kinase inhibitor (IC50s = 25, 8, 61, 122, 136, and 133 nM for ACK1, GCK, Bcr-AblT315I, Bcr-AblE255V, Bcr-AblG250E, and c-Abl, respectively). It also inhibits several additional kinases in a panel by greater than 50% when used at a concentration of 10 µM. GNF-7 inhibits the growth of Ba/F3 cells...
| Schlagworte: | N-[3-[1,4-dihydro-1-methyl-7-[(6-methyl-3-pyridinyl)amino]-2-oxopyrimido[4,5-d]pyrimidin-3(2H)-yl]-4-methylphenyl]-3-(trif... |
| Anwendung: | Ack1 / GCK inhibitor |
| CAS | 839706-07-9 |
| MW: | 547.5 D |
ab 43,00 €
Anti-TNK2
Artikelnummer: E-AB-12226.120
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a...
| Schlagworte: | Anti-TNK2, Anti-ACK1, Anti-ACK-1, Anti-Activated CDC42 kinase 1, Anti-Tyrosine kinase non-receptor protein 2, TNK2... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-TNK2
Artikelnummer: E-AB-15457.120
This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs. This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain. The protein may be involved in a...
| Schlagworte: | Anti-TNK2, Anti-ACK1, Anti-ACK-1, Anti-Activated CDC42 kinase 1, Anti-Tyrosine kinase non-receptor protein 2, TNK2... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 71,00 €
Anti-ACK1
Artikelnummer: ARG59774.100
Protein function: Non-receptor tyrosine-protein and serine/threonine- protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors. Phosphorylates AKT1, AR, MCF2, WASL and WWOX. Implicated in...
| Schlagworte: | Anti-TNK2, Anti-ACK1, Anti-ACK-1, Anti-Activated CDC42 kinase 1, Anti-Tyrosine kinase non-receptor protein 2 |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
624,00 €
ACK1 (Phospho-Tyr284) Colorimetric Cell-Based ELISA Kit
Artikelnummer: G-CBCAB01332.96
ACK1 (Phospho-Tyr284) Colorimetric Cell-Based ELISA Kit Protein function: Non-receptor tyrosine-protein and serine/threonine-protein kinase that is implicated in cell spreading and migration, cell survival, cell growth and proliferation. Transduces extracellular signals to cytosolic and nuclear effectors....
| Schlagworte: | TNK2, ACK1, ACK-1, Activated CDC42 kinase 1, Tyrosine kinase non-receptor protein 2 |
| Anwendung: | In-cell ELISA |
641,00 €
Anti-TNK2
Artikelnummer: G-CAB2526.100
| Anwendung: | IF, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €
Anti-phospho-TNK2-Y284
Artikelnummer: G-CABP0589.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 352,00 €