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Anti-BRD2
Anti-BRD2

Artikelnummer: A302-583A

Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
Schlagworte: Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein
Anwendung: WB, IP
Wirt: Rabbit
Spezies-Reaktivität: human, mouse
ab 164,00 €
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RVX-297
RVX-297

Artikelnummer: Cay38777-5

RVX-297 is an inhibitor of the bromodomain and extra-terminal domain (BET) family protein bromodomain 2 (BD2). It inhibits BD2 in bromodomain-containing protein 2 (BRD2), BRD3, and BRD4, (IC50s = 0.08, 0.05, and 0.02 µM, respectively) and is selective for BD2 over BD1 (IC50s = 3.76, 2.34, and 1.16 µM for BRD2, BRD3,...
Schlagworte: 2-[3,5-dimethyl-4-[2-(1-pyrrolidinyl)ethoxy]phenyl]-5,7-dimethoxy-4(3H)-quinazolinone
Anwendung: BD2 bromodomain inhibitor
CAS 1044871-04-6
MW: 423.5 D
ab 101,00 €
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(+)-JQ1 Bromodomain Inhibitor
(+)-JQ1 Bromodomain Inhibitor

Artikelnummer: BPS-27402

(+)-JQ1 is a specific inhibitor of the BET family of acetyl-lysine recognition motifs, including the BRD2, BRD3, BRD4 and BRDT bromodomains. (+)-JQ1 has been shown to inhibit BRD4 (BD1) with a Kd of 50 nM, and BRD4 (BD2) with a Kd of 90 nM.
Schlagworte: BET inhibitor, Bromodomain inhibitor,
Anwendung: BRD inhibitor
MW: 456.99 D
202,00 €
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OTX015
OTX015

Artikelnummer: Cay15947-1

The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. OTX015 is an...
Schlagworte: (-)-OTX015, HY-15743,...
Anwendung: BRD2 / BRD3 / BRD4 inhibitor
CAS 202590-98-5
MW: 492 D
ab 66,00 €
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BRD2 (339-459), His-tag, human recombinant protein
BRD2 (339-459), His-tag, human recombinant protein

Artikelnummer: BPS-31020-1

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Schlagworte: BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein,
Anwendung: Binding assays, inhibitor screening, selectivity profiling
MW: 15.1 kD
ab 208,00 €
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(+)-JQ-1
(+)-JQ-1

Artikelnummer: LKT-J6400.1

JQ-1 is a triazolothienodiazepine compound that inhibits the BET bromodomain (BRD) family of proteins. Although it is a diazepine-like compound, JQ-1 exhibits no sedative or anxiolytic efficacy. JQ-1 was initially in development as a non-hormonal male contraceptive, inhibiting bromodomain testis-specific protein...
Anwendung: Bromodomain Inhibitor
CAS 1268524-70-4
MW: 456.99 D
ab 112,00 €
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Anti-BRD2
Anti-BRD2

Artikelnummer: A302-582A

Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
Schlagworte: Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein
Anwendung: WB, IP, ICC-IF
Wirt: Rabbit
Spezies-Reaktivität: human
ab 164,00 €
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I-BET151
I-BET151

Artikelnummer: Cay11181-1

The bromodomain and extra terminal domain (BET) family of proteins including BRD2, BRD3, and BRD4 play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. I-BET151 is an...
Schlagworte: GSK1210151A, 7,3,5-dimethyl-4-isoxazolyl-1,3-dihydro-8-methoxy-1-[1R-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one
Anwendung: pan-BET family inhibitor
CAS 1300031-49-5
MW: 415.5 D
ab 48,00 €
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Anti-BRD2
Anti-BRD2

Artikelnummer: A300-204A

Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
Schlagworte: Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein
Anwendung: WB, IP
Wirt: Goat
Spezies-Reaktivität: human
ab 164,00 €
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Anti-BRD2 Recombinant Monoclonal
Anti-BRD2 Recombinant Monoclonal

Artikelnummer: A700-008

Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
Schlagworte: Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein
Anwendung: WB, IP, FC
Wirt: Rabbit
Spezies-Reaktivität: human
ab 172,00 €
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SHP-1, active human recombinant protein
SHP-1, active human recombinant protein

Artikelnummer: BPS-30021

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Schlagworte: BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein,
Anwendung: Enzyme kinetics, dephosphorylation, inhibitor screening
MW: 95 kD
481,00 €
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PFI-1
PFI-1

Artikelnummer: Cay11155-5

Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of bromodomain-containing protein (BRD) 2 and BRD4 bind acetylated histone tails, which couples...
Schlagworte: PF-06405761, 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide
Anwendung: Bromodomain inhibitor
CAS 1403764-72-6
MW: 347.4 D
ab 52,00 €
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