Zu "K08871" wurden 83 Artikel gefunden!
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Anti-BRD2
Artikelnummer: A302-583A
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
OTX015
Artikelnummer: Cay15947-1
The bromodomain and extra terminal domain (BET) family of proteins, including BRD2, BRD3, and BRD4, play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. OTX015 is an...
| Schlagworte: | (-)-OTX015, HY-15743,... |
| Anwendung: | BRD2 / BRD3 / BRD4 inhibitor |
| CAS | 202590-98-5 |
| MW: | 492 D |
ab 73,00 €
(+)-JQ-1
Artikelnummer: LKT-J6400.1
JQ-1 is a triazolothienodiazepine compound that inhibits the BET bromodomain (BRD) family of proteins. Although it is a diazepine-like compound, JQ-1 exhibits no sedative or anxiolytic efficacy. JQ-1 was initially in development as a non-hormonal male contraceptive, inhibiting bromodomain testis-specific protein...
| Anwendung: | Bromodomain Inhibitor |
| CAS | 1268524-70-4 |
| MW: | 456.99 D |
ab 118,00 €
I-BET151
Artikelnummer: Cay11181-1
The bromodomain and extra terminal domain (BET) family of proteins including BRD2, BRD3, and BRD4 play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interaction by controlling the assembly of histone acetylation-dependent chromatin complexes. I-BET151 is an...
| Schlagworte: | GSK1210151A, 7,3,5-dimethyl-4-isoxazolyl-1,3-dihydro-8-methoxy-1-[1R-1-(2-pyridinyl)ethyl]-2H-imidazo[4,5-c]quinolin-2-one |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.5 D |
ab 54,00 €
Anti-BRD2
Artikelnummer: A302-582A
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | WB, IP, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-BRD2
Artikelnummer: A300-204A
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | WB, IP |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-BRD2 Recombinant Monoclonal
Artikelnummer: A700-008
Protein function: May play a role in spermatogenesis or folliculogenesis. Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly. [The UniProt Consortium]
| Schlagworte: | Anti-BRD2, Anti-O27.1.1, Anti-KIAA9001, Anti-Bromodomain-containing protein 2, Anti-Really interesting new gene 3 protein |
| Anwendung: | WB, IP, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 172,00 €
SHP-1, active human recombinant protein
Artikelnummer: BPS-30021
.
| Schlagworte: | BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein, |
| Anwendung: | Enzyme kinetics, dephosphorylation, inhibitor screening |
| MW: | 95 kD |
491,00 €
PFI-1
Artikelnummer: Cay11155-5
Bromodomains recognize acetylated lysine residues and recruit regulatory complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. The isolated individual or tandem bromodomains of bromodomain-containing protein (BRD) 2 and BRD4 bind acetylated histone tails, which couples...
| Schlagworte: | PF-06405761, 2-methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-6-yl)benzenesulfonamide |
| Anwendung: | Bromodomain inhibitor |
| CAS | 1403764-72-6 |
| MW: | 347.4 D |
ab 57,00 €
BRD2 (65-187), His-tag, human recombinant protein
Artikelnummer: BPS-31022
.
| Schlagworte: | BRD2, O27.1.1, KIAA9001, Bromodomain-containing protein 2, Really interesting new gene 3 protein, |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| MW: | 15.5 kD |
461,00 €
I-BET151 (GSK1210151A)
Artikelnummer: BPS-27629-1
I-BET151(GSK1210151A) is a BET bromodomain inhibitor. I-BET151 displays potent binding affinity to BRD2, BRD3 and BRD4 with Kd of 0.02-0.1 µM. I-BET151 (0.5 or 5 µM) inhibits the binding of BETs (BRD2, BRD3, BRD4, and BRD9) but not the binding of 23 other bromodomain proteins. I-BET151 also blocks recruitment of BET...
| Schlagworte: | I-BET151, GSK1210151A,... |
| Anwendung: | BET bromodomain inhibitor |
| MW: | 415.4 D |
ab 410,00 €
I-BET151
Artikelnummer: LKT-I0516.10
I-BET-151 is a BET bromodomain (BRD) inhibitor that inhibits BRD2, BRD3, and BRD4. I-BET-151 exhibits anticancer chemotherapeutic and anti-inflammatory activities. In vitro and in vivo, this compound induces apoptosis and inhibits cellular proliferation in various cancer models. I-BET-151 inhibits recruitment of the...
| Schlagworte: | GSK-1210151A, GSK1210151A |
| Anwendung: | pan-BET family inhibitor |
| CAS | 1300031-49-5 |
| MW: | 415.44 D |
ab 248,00 €