Zu "K08855" wurden 27 Artikel gefunden!
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SGC-GAK-1
Artikelnummer: Cay33229-5
SGC-GAK-1 is an inhibitor of cyclin G-associated kinase (GAK, Ki = 3.1 nM). It is greater than 50-fold selective for GAK over a panel of 400 kinases at 1 µM but does bind to RIPK2 in a bioluminescence resonance energy transfer (BRET) engagement assay (IC50 = 360 nM). SCG-GAK-1 reduces the viability of LNCaP and...
| Schlagworte: | 6-bromo-N-(3,4,5-trimethoxyphenyl)-4-quinolinamine |
| Anwendung: | GAK inhibitor |
| CAS | 2226517-76-4 |
| MW: | 389.2 D |
ab 56,00 €
Anti-GAK
Artikelnummer: A304-268A
Protein function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin- coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. [The UniProt Consortium]
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Anti-GAK
Artikelnummer: ATA-HPA027405.100
Protein function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2)....
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-GAK
Artikelnummer: ATA-HPA027459.100
Protein function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2)....
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-GAK
Artikelnummer: ATA-HPA027463.100
Protein function: Associates with cyclin G and CDK5. Seems to act as an auxilin homolog that is involved in the uncoating of clathrin-coated vesicles by Hsc70 in non-neuronal cells. Expression oscillates slightly during the cell cycle, peaking at G1. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2)....
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase |
| Anwendung: | IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Cyclin-G-associated kinase (GAK), partial, human,...
Artikelnummer: CSB-EP009190HUh2.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-314aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged and C-terminal Avi-tagged. Target Protein Sequence: LRVRRVLAEG GFAFVYEAQD VGSGREYALK RLLSNEEEKN RAIIQEVCFM KKLSGHPNIV QFCSAASIGK EESDTGQAEF LLLTELCKGQ LVEFLKKMES RGPLSCDTVL...
| Schlagworte: | GAK, EC=2.7.11.1, Cyclin-G-associated kinase, Recombinant Human Cyclin-G-associated kinase (GAK), partial |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 40.8 kD |
ab 292,00 €
Cyclin-G-associated kinase (GAK), partial, Biotinylated,...
Artikelnummer: CSB-EP009190HUm5-B.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 40-314aa. Protein Length: Partial. Tag Info: N-terminal GST-tagged and C-terminal Avi-tagged. Target Protein Sequence: LRVRRVLAEG GFAFVYEAQD VGSGREYALK RLLSNEEEKN RAIIQEVCFM KKLSGHPNIV QFCSAASIGK EESDTGQAEF LLLTELCKGQ LVEFLKKMES RGPLSCDTVL KIFYQTCRAV...
| Schlagworte: | GAK, EC=2.7.11.1, Cyclin-G-associated kinase, Recombinant Human Cyclin-G-associated kinase (GAK), partial, Biotinylated |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 60.8 kD |
2.356,00 €
Anti-GAK
Artikelnummer: CSB-PA002632.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase, Auxilin 2 antibody, Cyclin G associated kinase antibody,... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
126,00 €
Anti-GAK
Artikelnummer: CSB-PA100194.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
| Schlagworte: | Anti-GAK, EC=2.7.11.1, Anti-Cyclin-G-associated kinase, Auxilin 2 antibody, Cyclin G associated kinase antibody,... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
284,00 €
SGC-GAK-1
Artikelnummer: TGM-T5169-100mg
Description: SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM). Target: Serine/threonin kinase. Smiles: COc1cc(Nc2ccnc3ccc(Br)cc23)cc(OC)c1OC. References: Asquith CRM, et al. SGC-GAK-1: A Chemical Probe for Cyclin G Associated Kinase (GAK). J Med Chem. 2019 Feb 26.
| Anwendung: | GAK inhibitor |
| CAS | 2226517-76-4 |
| MW: | 389.24 D |
ab 41,00 €
GAK inhibitor 49
Artikelnummer: TGM-T8535-100mg
Description: GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM, Ki: 0.54 nM ). Target: Serine/threonin kinase. Smiles: COc1cc(Nc2ccnc3cc(OC)c(OC)cc23)cc(OC)c1OC. References: Asquith CRM, et al. Identification and Optimization of 4-Anilinoquinolines as...
| Anwendung: | GAK inhibitor |
| CAS | 319492-82-5 |
| MW: | 370.4 D |
ab 49,00 €
GAK inhibitor 2
Artikelnummer: TGM-T61703-100mg
Description: GAK inhibitor 2 (Compound 14g) is a highly potent inhibitor of cyclin G-associated kinase (GAK) with an IC50 of 0.024 µM and exhibits remarkable antiviral activity against dengue virus (DENV) with an EC50 of 1.049 µM [1]. Target: Others. Smiles:...
| Anwendung: | GAK inhibitor |
| CAS | 2396706-31-1 |
| MW: | 385.48 D |
ab 1.440,00 €