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Zu "K08853" wurden 41 Artikel gefunden!
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Artikelnummer: TGM-T12885-100mg
Description: SGC-AAK1-1, a potent and selective inhibitor of AAK1 (AP2-associated kinase 1), has an IC50 of 270 nM and a Ki of 9 nM, and serves as a chemical probe. Target: AAK1 (AP2 associated kinase 1). Smiles: CCN(CC)S(=O)(=O)Nc1cccc(c1)-c1ccc2c(NC(=O)C3CC3)n[nH]c2c1. References: Agajanian MJ, et al. WNT...
Anwendung: | AAK1 / BMP2K dual inhibitor |
CAS | 2247894-32-0 |
MW: | 427.52 D |
ab 40,00 €
Artikelnummer: TGM-T15781-100mg
Description: LP-935509 is highly brain-penetrant and reverses fully established pain behavior following the SNL procedure. LP-935509 is an effective inhibitor of BIKE (IC50=14 nM) and a modest inhibitor of cyclin G-associated kinase(GAK, IC50=320 nM). LP-935509 is also a ATP-competitive inhibitor of adapter...
Anwendung: | AAK1 / BIKe inhibitor |
CAS | 1454555-29-3 |
MW: | 396.44 D |
ab 34,00 €
Artikelnummer: CSB-PA000776.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK 1 antibody, Aak1... |
Anwendung: | ELISA, WB, IHC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 126,00 €
Artikelnummer: CSB-PA183703.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.1mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Affinity purification. Target Name: AAK1. Antigen Species: Human
Schlagworte: | Anti-AAK1, Anti-KIAA1048, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK 1 antibody, Aak1... |
Anwendung: | ELISA, WB, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: CSB-PA903610.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK 1 antibody, Aak1... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: Cay41118-10
SGC-AAK1-1 is a dual inhibitor of AP2-associated protein kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K, Kis = 9.1 and 17 nM, respectively). It is selective for AAK1 and BMP2K over cyclin G-associated kinase (GAK) and serine/threonine kinase 16 (STK16, Kis = 1,700 and 270 nM, respectively). See the Structural...
Schlagworte: | N-[6-[3-[[(diethylamino)sulfonyl]amino]phenyl]-1H-indazol-3-yl]-cyclopropanecarboxamide |
Anwendung: | AAK1 / BMP2K dual inhibitor |
CAS | 2247894-32-0 |
MW: | 427.5 D |
ab 107,00 €
Artikelnummer: A302-145A
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 178,00 €
Artikelnummer: A302-146A
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
Anwendung: | WB, IP |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 178,00 €
Artikelnummer: ARG65033.100
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
Anwendung: | ELISA, WB |
Wirt: | Goat |
Spezies-Reaktivität: | human |
822,00 €
Artikelnummer: 600-401-X53
Anti-Aak1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Aak1 from other sources has not been determined. Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2)...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
834,00 €
Artikelnummer: 600-401-X54
Anti-Aak1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Aak1 from other sources has not been determined. Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2)...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
Anwendung: | ELISA, IFM, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
834,00 €
Artikelnummer: NSJ-R34135-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: AP2 associated kinase 1 Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity...
Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK1 Antibody |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
790,00 €