Zu "K08853" wurden 43 Artikel gefunden!
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NEU
BMS 911172
Artikelnummer: Cay45308-10
An AAK1 inhibitor that reduces phosphorylation of AP2M2 in HEK293 cells overexpressing AAK1 and AP2M2 (IC50 = 0.051 µM), selective for AAK1 over a panel of 219 kinases, including BIKE, GAK, and STK16 (IC550 = 0.120, 1.06, and 15.8 µM, respectively), inhibits AP2M2 phosphorylation in mouse brain lysates (ED50 = 6...
| Schlagworte: | 2R-amino-N-[3-(difluoromethoxy)-4-(5-oxazolyl)phenyl]-4-methyl-pentanamide |
| Anwendung: | AP2-associated protein kinase 1 (AAK1) inhibitor |
| CAS | 1644248-18-9 |
| MW: | 339.34 D |
ab 236,00 €
BMS 986176
Artikelnummer: Cay43668-1
An AAK1 inhibitor (IC50 = 2 nM), increases the latency to paw withdrawal in a rat model of streptozotocin-induced diabetic neuropathic pain at 0.3 or 3 mg/kg
| Schlagworte: | LX9211, (2S)-1-[[2',6-bis(difluoromethyl)[2,4'-bipyridin]-5-yl]oxy]-2,4-dimethyl-2-pentanamine |
| Anwendung: | AAK1 (AP2-associated kinase) inhibitor |
| CAS | 1815613-42-3 |
| MW: | 385.41 D |
ab 112,00 €
Anti-AAK1
Artikelnummer: A302-145A
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-AAK1
Artikelnummer: A302-146A
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-AAK1, Internal
Artikelnummer: ARG65033.100
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis. Isoform 1 and isoform 2 display similar levels of kinase activity...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Anti-Aak1
Artikelnummer: 600-401-X53
Anti-Aak1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Aak1 from other sources has not been determined. Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2)...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-Aak1
Artikelnummer: 600-401-X54
Anti-Aak1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Aak1 from other sources has not been determined. Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2)...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | ELISA, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Anti-AAK1
Artikelnummer: NSJ-R34135-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: AP2 associated kinase 1 Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK1 Antibody |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-AAK1
Artikelnummer: E-AB-52133.120
Adaptor-related protein complex 2 (AP-2 complexes) functions during receptor-mediated endocytosis to trigger clathrin assembly, interact with membrane-bound receptors, and recruit encodytic accessory factors. This gene encodes a member of the SNF1 subfamily of Ser/Thr protein kinases. The protein interacts with and...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, EC=2.7.11.1, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1, AAK1... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-AAK1
Artikelnummer: ATA-HPA017931.100
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis (PubMed:17494869, PubMed:11877457, PubMed:11877461,...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-AAK1
Artikelnummer: ATA-HPA020289.100
Protein function: Regulates clathrin-mediated endocytosis by phosphorylating the AP2M1/mu2 subunit of the adaptor protein complex 2 (AP-2) which ensures high affinity binding of AP-2 to cargo membrane proteins during the initial stages of endocytosis (PubMed:17494869, PubMed:11877457, PubMed:11877461,...
| Schlagworte: | Anti-AAK1, Anti-KIAA1048, Anti-Adaptor-associated kinase 1, Anti-AP2-associated protein kinase 1 |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €
SGC-AAK1-1
Artikelnummer: Cay41118-10
SGC-AAK1-1 is a dual inhibitor of AP2-associated protein kinase 1 (AAK1) and BMP2-inducible kinase (BMP2K, Kis = 9.1 and 17 nM, respectively). It is selective for AAK1 and BMP2K over cyclin G-associated kinase (GAK) and serine/threonine kinase 16 (STK16, Kis = 1,700 and 270 nM, respectively). See the Structural...
| Schlagworte: | N-[6-[3-[[(diethylamino)sulfonyl]amino]phenyl]-1H-indazol-3-yl]-cyclopropanecarboxamide |
| Anwendung: | AAK1 / BMP2K dual inhibitor |
| CAS | 2247894-32-0 |
| MW: | 427.5 D |
ab 116,00 €