Zu "K08845" wurden 48 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Anti-ARAF / A-Raf
Artikelnummer: NSJ-RQ4970
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase A-Raf or simply A-Raf is an enzyme that in humans is encoded by the ARAF gene. It is mapped to Xp11.3. This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and...
| Schlagworte: | Anti-ARAF, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
aRAF, active human recombinant protein
Artikelnummer: BPS-40010
Active human A-RAF (GenBank Accession No. NM_001654), amino acids 282-end, containing the mutations YY301-302DD, MW=63.6 kDa, expressed in an Baculovirus infected Sf9 cell expression system.
| Schlagworte: | ARAF, ARAF1, EC=2.7.11.1, Proto-oncogene Pks, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1, Serine/threonine-protein... |
| Anwendung: | Enzyme kinetics, inhibitor screening |
| MW: | 63.6 kD |
581,00 €
LY3009120
Artikelnummer: Cay21504-5
LY3009120 is an inhibitor of Raf kinases, including A-Raf, B-Raf, and c-Raf (IC50s = 44, 31-47, and 42 nM, respectively, in whole cell lysates). It also inhibits B-Raf mutants V600E and V600E+G468A (IC50s = 5.8 and 17 nM, respectively, in biochemical assays). LY3009120 induces Raf dimerization and, unlike...
| Schlagworte: | DP-4978, N-(3,3-dimethylbutyl)-N'-[2-fluoro-4-methyl-5-[7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl]phenyl]-urea |
| Anwendung: | Raf inhibitor |
| CAS | 1454682-72-4 |
| MW: | 424.5 D |
ab 211,00 €
Anti-A-RAF
Artikelnummer: A303-103A
Protein function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. [The UniProt Consortium]
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-A-RAF
Artikelnummer: A303-104A
Protein function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. [The UniProt Consortium]
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
MLN2480
Artikelnummer: Cay19675-1
MLN2480 is an orally bioavailable pan-Raf kinase inhibitor that inhibits MAP kinase pathway signaling in BRAF-mutant melanoma models. It shows antitumor activity in melanoma, colon, lung, and pancreatic cancer xenograft models. MLN2480 demonstrates synergistic activity with TAK-733, an allosteric MEK kinase...
| Schlagworte: | BIIB-024, TAK-580,... |
| Anwendung: | Selective pan-Raf inhibitor |
| CAS | 1096708-71-2 |
| MW: | 506.3 D |
ab 68,00 €
L-779,450
Artikelnummer: Cay17807-1
L-779,450 is an ATP-competitive B-Raf inhibitor (IC50 = 10 nM, Kd = 2.4 nM) that displays >7, >30, and >70-fold selectivity over p38alpha, GSK3beta, and Lck, respectively. It has been shown to inhibit cell proliferation both in B-Raf mutated and wild-type melanoma cell lines, as well as to enhance tumor necrosis...
| Schlagworte: | Raf Kinase Inhibitor IV, 2-chloro-5-[2-phenyl-4-(4-pyridinyl)-1H-imidazol-5-yl]-phenol |
| Anwendung: | Raf kinase inhibitor |
| CAS | 303727-31-3 |
| MW: | 347.8 D |
ab 49,00 €
Anti-A-Raf, clone IBA-1
Artikelnummer: NSJ-RQ5320
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. The ARAF proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. [RefSeq] Protein function: Involved in the transduction of mitogenic signals from the cell membrane...
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
A-RAF (Phospho-Tyr302) Colorimetric Cell-Based ELISA Kit
Artikelnummer: G-CBCAB01365.96
A-RAF (Phospho-Tyr302) Colorimetric Cell-Based ELISA Kit Protein function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. [The UniProt Consortium]
| Schlagworte: | ARAF, ARAF1, EC=2.7.11.1, Proto-oncogene Pks, Proto-oncogene A-Raf, Proto-oncogene A-Raf-1, Serine/threonine-protein... |
| Anwendung: | In-cell ELISA |
1.027,00 €
Anti-ARAF
Artikelnummer: ATA-HPA046188.100
Protein function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 86% and to...
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | ICC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
Anti-ARAF
Artikelnummer: ATA-HPA066326.100
Protein function: Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May also regulate the TOR signaling cascade. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 83% and to...
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-ARAF
Artikelnummer: CSB-PA011272.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ARAF, Anti-ARAF1, EC=2.7.11.1, Anti-Proto-oncogene Pks, Anti-Proto-oncogene A-Raf, Anti-Proto-oncogene A-Raf-1,... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
ab 126,00 €