Zu "K08823" wurden 65 Artikel gefunden!
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Adavivint
Artikelnummer: Cay43927-1
Adavivint is an inhibitor of Wnt signaling (EC50 = 19. nM in a reporter assay using SW480 cells). It inhibits CMGC family kinases, including CDC-like kinase 2 (Clk2) and dual-specificity tyrosine phosphorylation-regulated kinase 1A (DYRK1A, IC50s = 7. and 26. nM, respectively), as well as Clk1, Clk3, Clk4, DYRK1B,...
| Schlagworte: | Lorecivivint, SM-04690,... |
| Anwendung: | Wnt signaling inhibitor |
| CAS | 1467093-03-3 |
| MW: | 505.56 D |
ab 38,00 €
TG003
Artikelnummer: AG-CR1-3656-M005
Solid. Soluble in DMSO (20mg/ml), ethanol (15mg/ml) or DMF (15mg/ml). Potent, specific, reversible and ATP-competitive cell permeable inhibitor of Cdc2-like kinase (Clk) (IC50=15nM, 20nM, 200nM and >,10µM for mClk4, mClk1, mClk2 and mClk3, respectively). Cdc2-like kinase (Clk), among a number of other kinases,...
| Schlagworte: | (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one |
| Anwendung: | Potent specific reversible and ATP-competitive cell permeable Clk inhibitor |
| CAS | 300801-52-9 |
| MW: | 249,3 D |
ab 28,00 €
ML-167
Artikelnummer: Cay18098-10
The Cdc2-like kinases (Clks) and the dual-specificity tyrosine phosphorylation-regulated kinases (DYRKs) are involved in regulating gene splicing. Clks phosphorylate serine/arginine-rich proteins, which are a major component of the spliceosome, whereas DYRKs interact with and activate splicing factors. ML167 is a...
| Schlagworte: | CID 44968231, 5-[4-[[(5-methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol |
| Anwendung: | Clk4 inhibitor |
| CAS | 1285702-20-6 |
| MW: | 335.4 D |
ab 40,00 €
CC-671
Artikelnummer: Cay26184-1
CC-671 is a dual inhibitor of the spindle assembly checkpoint kinase Mps1/TTK and Cdc2-like kinase (Clk2, IC50s = 5 and 3 nM, respectively). It is selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 µM, but does inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM,...
| Schlagworte: | 4-[[4-(cyclopentyloxy)-5-(2-methyl-6-benzoxazolyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl]amino]-3-methoxy-N-methyl-benzamide |
| Anwendung: | TTK / CLK2 inhibitor |
| CAS | 1618658-88-0 |
| MW: | 512.6 D |
ab 49,00 €
Anti-phospho-cdc2 (Thr15)
Artikelnummer: 600-401-160
Anti-cdc2 pT15 Antibody is directed against rat cdc2 protein phosphorylated ar T15. The antibody was prepared from monospecific antiserum by immunoaffinity chromatography using phospho peptide coupled to agarose beads followed by solid phase adsorption(s) against non-phospho peptide and non-specific peptide to...
| Schlagworte: | Anti-phospho-Clk2, Anti-phospho-LOC365842, Anti-phospho-CDC-like kinase 2 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | rat, human, Xenopus |
877,00 €
CC-671
Artikelnummer: LKT-C086007.1
TTK/CLK2 inhibitor.
| Schlagworte: | CC 671, CC671 |
| Anwendung: | TTK / CLK2 inhibitor |
| CAS | 1618658-88-0 |
| MW: | 512.57 D |
ab 180,00 €
Anti-CLK2
Artikelnummer: E-AB-53303.120
This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have...
| Schlagworte: | Anti-CLK2, EC=2.7.12.1, Anti-CDC-like kinase 2, Anti-Dual specificity protein kinase CLK2, CLK2 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Anti-CLK2
Artikelnummer: ARG66787.100
Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause...
| Schlagworte: | Anti-CLK2, EC=2.7.12.1, Anti-CDC-like kinase 2, Anti-Dual specificity protein kinase CLK2 |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
658,00 €
Anti-CLK2
Artikelnummer: NSJ-RQ5967
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Dual specificity protein kinase CLK2 is an enzyme that in humans is encoded by the CLK2 gene. It is mapped to 1q22. This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this...
| Schlagworte: | Anti-CLK2, EC=2.7.12.1, Anti-CDC-like kinase 2, Anti-Dual specificity protein kinase CLK2, CLK2 Antibody |
| Anwendung: | WB, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-CLK3
Artikelnummer: ATA-HPA046817.100
Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause...
| Schlagworte: | Anti-CLK3, EC=2.7.12.1, Anti-CDC-like kinase 3, Anti-Dual specificity protein kinase CLK3 |
| Anwendung: | WB, IHC, ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-CLK2
Artikelnummer: ATA-HPA055366.100
Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause...
| Schlagworte: | Anti-CLK2, EC=2.7.12.1, Anti-CDC-like kinase 2, Anti-Dual specificity protein kinase CLK2 |
| Anwendung: | ICC, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
463,00 €
Anti-CLK2
Artikelnummer: ATA-HPA059507.100
Protein function: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause...
| Schlagworte: | Anti-CLK2, EC=2.7.12.1, Anti-CDC-like kinase 2, Anti-Dual specificity protein kinase CLK2 |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €