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Zu "K08803" wurden 120 Artikel gefunden!
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Artikelnummer: Cay42246-5
A DAPK1 (IC50 = 200 nM) and DAPK3 inhibitor, selectively binds to DAPK1, DAPK2, and DAPK3 (Kds = 300, 79, and 280 nM, respectively) over Pim-1, Pim-2, and Pim-3 (Kds = 1,800, 6,500, and 810 nM, respectively) but does inhibit Pim-3 (IC50 = 200 nM), inhibits phosphorylation of RLC20 in primary human coronary artery...
| Schlagworte: | 2-[[1-(3-chlorophenyl)-4,5-dihydro-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-6-yl]thio]-propanamide |
| Anwendung: | DAPK1/DAPK3 inhibitor |
| CAS | 1030203-81-6 |
| MW: | 349.8 D |
ab 50,00 €
Artikelnummer: Cay42378-10
TC-DAPK6 is an inhibitor of death-associated protein kinase 1 (DAPK1) and DAPK3 (IC50s = 69 and 225 nM, respectively). It is selective for DAPK1 and DAPK3 over 47 other kinases at 10 µM. Hollow mesoporous silica nanocarriers (HMSNs) encapsulating TC-DAPK6 increase the latency to fall and distance traveled on the rod...
| Schlagworte: | 2-(2-phenylethenyl)-4-(3-pyridinylmethylene)-5(4H)-oxazolone |
| Anwendung: | DAPK1 / DAPK3 inhibitor |
| CAS | 315694-89-4 |
| MW: | 276.29 D |
ab 44,00 €
Artikelnummer: A304-221A-T
Protein function: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase- dependent) apoptotic and type II (caspase-independent)...
| Schlagworte: | Anti-Dlk, Anti-ZIPK, Anti-DAPK3, Anti-ZIP-kinase, Anti-MYPT1 kinase, Anti-DAP kinase 3, Anti-DAP-like kinase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Artikelnummer: ARG54388.50
Protein function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent,...
| Schlagworte: | Anti-DRP-1, Anti-DAPK2, EC=2.7.11.1, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
625,00 €
Artikelnummer: ARG63157.100
Protein function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent,...
| Schlagworte: | Anti-DRP-1, Anti-DAPK2, EC=2.7.11.1, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
871,00 €
Artikelnummer: A304-222A
Protein function: Serine/threonine kinase which is involved in the regulation of apoptosis, autophagy, transcription, translation and actin cytoskeleton reorganization. Involved in the regulation of smooth muscle contraction. Regulates both type I (caspase- dependent) apoptotic and type II (caspase-independent)...
| Schlagworte: | Anti-Dlk, Anti-ZIPK, Anti-DAPK3, Anti-ZIP-kinase, Anti-MYPT1 kinase, Anti-DAP kinase 3, Anti-DAP-like kinase,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Artikelnummer: BPS-40051
Human Death-Associated Protein Kinase-1 (DAPK1), amino acids 2-363, with N-terminal GST-tag, expressed in Baculovirus-infected Sf9 cells.
| Schlagworte: | DAPK, DAPK1, EC=2.7.11.1, DAP kinase 1, Death-associated protein kinase 1, |
| Anwendung: | Enzyme kinetics, inhibitor screening, profiling |
| MW: | 67 kD |
536,00 €
Artikelnummer: 600-401-AS5
Anti-DAPK2 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. DAPK2 has no cross responses to DAPK1. Protein function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy....
| Schlagworte: | Anti-DAPK2, Anti-DRP-1, EC=2.7.11.1, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein... |
| Anwendung: | ELISA, IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
848,00 €
Artikelnummer: NSJ-R30635
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Death-associated protein kinase 2, also called DAP kinase related protein 1 (DRP-1), is an enzyme that in humans is encoded by the DAPK2 gene. This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a...
| Schlagworte: | Anti-DRP-1, Anti-DAPK2, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein kinase 2,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Artikelnummer: NSJ-R34353-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Death-associated protein kinase 2, DRP-1, DRP1 Protein function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival,...
| Schlagworte: | Anti-DRP-1, Anti-DAPK2, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein kinase 2,... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, mouse |
836,00 €
Artikelnummer: ARG58466.100
Protein function: Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell deaths signal, depending on the cellular setting. The former is caspase-dependent,...
| Schlagworte: | Anti-DAPK, Anti-DAPK1, EC=2.7.11.1, Anti-DAP kinase 1, Anti-Death-associated protein kinase 1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
707,00 €
Artikelnummer: E-AB-19487.120
This gene encodes a protein that belongs to the serine/threonine protein kinase family. This protein contains a N-terminal protein kinase domain followed by a conserved calmodulin-binding domain with significant similarity to that of death-associated protein kinase 1 (DAPK1), a positive regulator of programmed cell...
| Schlagworte: | Anti-DRP-1, Anti-DAPK2, Anti-DAP kinase 2, Anti-DAP-kinase-related protein 1, Anti-Death-associated protein kinase 2,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 89,00 €