Zu "K08799" wurden 50 Artikel gefunden!
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OTSSP167 (hydrochloride)
Artikelnummer: Cay16873-1
Maternal embryonic leucine zipper kinase (MELK) is a serine/threonine kinase that regulates signaling central to cell cycling, stem cell renewal, apoptosis, and other cellular processes. MELK is overexpressed in some forms of cancer, particularly those with aggressive undifferentiated tumors. OTSSP167 is a potent...
| Schlagworte: | 1-(6-(3,5-dichloro-4-hydroxyphenyl)-4-(((1r,4r)-4-((dimethylamino)methyl)cyclohexyl)amino)-1,5-naphthyridin-3-yl)ethan-1-o... |
| Anwendung: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.9 D |
ab 93,00 €
Anti-MELK
Artikelnummer: A303-136A
Protein function: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating...
| Schlagworte: | Anti-MELK, Anti-hMELK, Anti-hPK38, Anti-KIAA0175, Anti-pEg3 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase Eg3,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-MELK
Artikelnummer: A303-137A
Protein function: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating...
| Schlagworte: | Anti-MELK, Anti-hMELK, Anti-hPK38, Anti-KIAA0175, Anti-pEg3 kinase, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase Eg3,... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
MELK, GST-tag
Artikelnummer: BPS-40708
Recombinant human MELK, Genbank Accession #NM_014791, a.a. 1- 30, with an N-terminal GST-tag, MW = 61 kDa, expressed in Sf9 cells via a baculovirus expression system.
| Schlagworte: | MELK, hPK38, hMELK, KIAA0175, pEg3 kinase, EC=2.7.11.1, EC=2.7.10.2, Protein kinase Eg3, Protein kinase PK38,... |
| Anwendung: | Studying enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 61 kD |
901,00 €
Human MELK / Maternal embryonic leucine zipper kinase...
Artikelnummer: G-HUFI01450.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-MELK
Artikelnummer: NSJ-R34627-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Maternal embryonic leucine zipper kinase Protein function: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and...
| Schlagworte: | Anti-MELK, Anti-hPK38, Anti-hMELK, Anti-KIAA0175, EC=2.7.11.1, EC=2.7.10.2, Anti-pEg3 kinase, Anti-Protein kinase Eg3,... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-MELK
Artikelnummer: NSJ-F50146-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MELK contains 1 protein kinase domain that belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis. Protein function:...
| Schlagworte: | Anti-MELK, Anti-hPK38, Anti-hMELK, Anti-KIAA0175, EC=2.7.11.1, EC=2.7.10.2, Anti-pEg3 kinase, Anti-Protein kinase Eg3,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 361,00 €
Anti-MELK
Artikelnummer: NSJ-F50147-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. MELK Contains 1 protein kinase domain that Belongs to the Ser/Thr protein kinase family. It phosphorylates ZNF622 and may contribute to its redirection to the nucleus. MELK may also be involved in the inhibition of spliceosome assembly during mitosis. Protein function:...
| Schlagworte: | Anti-MELK, Anti-hPK38, Anti-hMELK, Anti-KIAA0175, EC=2.7.11.1, EC=2.7.10.2, Anti-pEg3 kinase, Anti-Protein kinase Eg3,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-Melk
Artikelnummer: NSJ-F53198-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of...
| Schlagworte: | Anti-Melk, Anti-mPK38, Anti-Kiaa0175, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase PK38, Anti-Tyrosine-protein kinase... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 361,00 €
Anti-Melk
Artikelnummer: NSJ-F53274-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of...
| Schlagworte: | Anti-Melk, Anti-mPK38, Anti-Kiaa0175, EC=2.7.11.1, EC=2.7.10.2, Anti-Protein kinase PK38, Anti-Tyrosine-protein kinase... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 361,00 €
OTSSP167 Hydrochloride
Artikelnummer: LKT-O783743.1
MELK inhibitor.
| Schlagworte: | OTS167 Hydrochloride, OTSSP167 (hydrochloride), OTSSP167 HCL |
| Anwendung: | MELK inhibitor |
| CAS | 1431698-10-0 |
| MW: | 523.88 D |
ab 123,00 €
Anti-MELK
Artikelnummer: ATA-HPA017214.100
Protein function: Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity, phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating...
| Schlagworte: | Anti-MELK, Anti-hMELK, Anti-hPK38, Anti-KIAA0175, EC=2.7.11.1, EC=2.7.10.2, Anti-pEg3 kinase, Anti-Protein kinase Eg3,... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €