Zu "K08791" wurden 44 Artikel gefunden!
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LATS-IN-1
Artikelnummer: Cay36623-5
LATS-IN-1 is an inhibitor of large tumor suppressor kinase 1 (LATS1) and LATS2 (IC50 = 2 nM for both), key regulators of Hippo regenerative signaling. It inhibits phosphorylation of YES1-associated transcriptional regulator (YAP1) in serum-starved HEK293A cells (EC50 = 510 nM). LATS-IN-1 (10 µM) increases the...
| Schlagworte: | LATS Inhibitor 1, TRULI, N-[3-(phenylmethyl)-2(3H)-thiazolylidene]-1H-pyrrolo[2,3-b]pyridine-3-carboxamide |
| Anwendung: | LATS1 / LATS2 inhibitor |
| CAS | 1424635-83-5 |
| MW: | 334.4 D |
ab 39,00 €
Anti-LATS1
Artikelnummer: A300-477A
Protein function: Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its...
| Schlagworte: | Anti-h-warts, EC=2.7.11.1, Anti-WARTS protein kinase, Anti-Large tumor suppressor homolog 1, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
Anti-LATS1
Artikelnummer: ATA-HPA031804.100
Protein function: Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its...
| Schlagworte: | Anti-h-warts, Anti-WARTS protein kinase, Anti-Large tumor suppressor homolog 1, Anti-Serine/threonine-protein kinase LATS1 |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 300,00 €
Anti-LATS1
Artikelnummer: A300-478A
Protein function: Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its...
| Schlagworte: | Anti-h-warts, EC=2.7.11.1, Anti-WARTS protein kinase, Anti-Large tumor suppressor homolog 1, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
LATS2, GST-Tag
Artikelnummer: BPS-79042
Human LATS2 protein with N-terminal GST-Tag, GenBank Accession No. NM_014572, a.a 480-1088, expressed in an Sf9 expression system. MW = 110 kDa.
| Schlagworte: | KPM, EC=2.7.11.1, Warts-like kinase, Large tumor suppressor homolog 2, Serine/threonine-protein kinase kpm,... |
| Anwendung: | Kinase assays, WB |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 110 kD |
862,00 €
LATS1, GST-Tag
Artikelnummer: BPS-79499
Human LATS1 protein with N terminal GST-Tag, GenBank Accession No. NM_004690, a.a 589-end, expressed in an Sf9 expression system. MW = 95 kDa.
| Schlagworte: | h-warts, WARTS protein kinase, Large tumor suppressor homolog 1, Serine/threonine-protein kinase LATS1, |
| Anwendung: | Kinase Assay, WB |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 95 kD |
862,00 €
Anti-LATS2
Artikelnummer: E-AB-15942.120
This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle...
| Schlagworte: | Anti-KPM, EC=2.7.11.1, Anti-Warts-like kinase, Anti-Large tumor suppressor homolog 2, Anti-Serine/threonine-protein kinase... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 71,00 €
Anti-LATS2
Artikelnummer: NSJ-F40138-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. LATS2 is a serine/threonine protein kinase belonging to the LATS tumor suppressor family. This protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation...
| Schlagworte: | Anti-KPM, EC=2.7.11.1, Anti-Warts-like kinase, Anti-Large tumor suppressor homolog 2, Anti-Serine/threonine-protein kinase... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 326,00 €
Anti-LATS1
Artikelnummer: NSJ-F50049-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase...
| Schlagworte: | Anti-h-warts, EC=2.7.11.1, Anti-WARTS protein kinase, Anti-Large tumor suppressor homolog 1, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 326,00 €
Anti-Lats2
Artikelnummer: NSJ-F47336-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with...
| Schlagworte: | EC=2.7.11.1, Anti-Large tumor suppressor homolog 2, Anti-Serine/threonine-protein kinase kpm,... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse |
ab 326,00 €
Anti-LATS1
Artikelnummer: NSJ-RQ4584
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Serine/threonine-protein kinase LATS1 is an enzyme that in humans is encoded by the LATS1 gene. It is mapped to 6q25.1. The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle...
| Schlagworte: | Anti-h-warts, EC=2.7.11.1, Anti-WARTS protein kinase, Anti-Large tumor suppressor homolog 1, Anti-Serine/threonine-protein... |
| Anwendung: | WB, IHC (paraffin), Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
LATS2, GST-Tag
Artikelnummer: BPS-100353
Human Large Tumor Suppressor Kinase 2 (LATS2) protein, also known as KPM and LATS, GenBank Accession No. NM_014572, a.a 480-1088(end), with an N-terminal GST-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW = 97 kDa.
| Schlagworte: | KPM, EC=2.7.11.1, Warts-like kinase, Large tumor suppressor homolog 2, Serine/threonine-protein kinase kpm,... |
| Anwendung: | Kinase assays |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 97 kD |
525,00 €