Zu "K08765" wurden 49 Artikel gefunden!
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(+)-Etomoxir (sodium salt)
Artikelnummer: Cay11969-5
(+)-Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase 1 (CPT1), an enzyme that combines fatty acyl-CoAs with carnitine for transport into the mitochondria for beta-oxidation. It inhibits fatty acid oxidation in hepatocytes in vitro (IC50s = 0.1, 1, and 10 µM for human, guinea pig, and rat...
| Schlagworte: | (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid monosodium salt |
| Anwendung: | Irreversible CPT1 / carnitine O-palmitoyltransferase 1 inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.7 D |
ab 118,00 €
(+)-Etomoxir
Artikelnummer: Cay9004470-10
(+)-Etomoxir is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and a prodrug form of (+)-etomoxir (Cay-11969). It is an ethyl ester that is cleaved by intracellular esterases to release the active inhibitor of CPT1. (+)-Etomoxir decreases palmitate (Cay-10010279) oxidation and increases glucose oxidation in...
| Schlagworte: | (R)-(+)-Etomoxir, (2R)-2-[6-(4-chlorophenoxy)hexyl]-2-oxiranecarboxylic acid, ethyl ester |
| Anwendung: | Carnitine palmitoyltransferase 1 (CPT1) inhibitor prodrug |
| CAS | 124083-20-1 |
| MW: | 326.81 D |
ab 127,00 €
Perhexiline (maleate)
Artikelnummer: Cay16982-1
Perhexiline is a carnitine palmitoyltransferase 1 (CPT1) and CPT2 inhibitor that was originally developed as an anti-anginal drug in the 1970s. It inhibits rat heart and liver CPT1 (IC50 = 77 and 148 µM, respectively) and rat heart CPT2 (IC50 = 79 µM). Inhibition of CPT reduces uptake of long-chain fatty acids into...
| Schlagworte: | 2-(2,2-dicyclohexylethyl)-piperidine, 2Z-butenedioate |
| Anwendung: | CPT1 / CPT2 inhibitor |
| CAS | 6724-53-4 |
| MW: | 393.6 D |
ab 54,00 €
(+)-Etomoxir . Na
Artikelnummer: AG-CR1-3688-M025
Irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1a) a mitochondrial enzyme involved in fatty acid beta-oxidation. CPR-1a on the outer face of the inner mitochondrial membrane, consequently prevents the formation of acyl carnitines, a step that is necessary for the transport of fatty acyl chains from...
| Schlagworte: | (R)-(+)-Etomoxir Na, (R)-(+)-2-[6-(4-Chlorophenoxy)hexyl]-oxirane-2-carboxylic acid sodium salt |
| Anwendung: | Irreversible carnitine palmitoyltransferase-1 (CPT-1a) inhibitor |
| CAS | 828934-41-4 |
| MW: | 320.8 D |
ab 77,00 €
Oxfenicine
Artikelnummer: Cay33698-5
Oxfenicine is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and a prodrug form of 4-hydroxyphenylglyoxylic acid. Oxfenicine is transaminated to 4-hydroxyphenylglyoxylic acid by branched-chain amino acid aminotransferase in rat heart homogenates. It inhibits fatty acid oxidation and increases carbohydrate...
| Schlagworte: | 4-hydroxy-L-Phenylglycine, p-hydroxy-L-Phenylglycine, UK 25842, alphaS-amino-4-hydroxy-benzeneacetic acid |
| Anwendung: | 4-hydroxyphenylglyoxylic acid CPT1 inhibitor, prodrug form |
| CAS | 32462-30-9 |
| MW: | 167.2 D |
ab 56,00 €
Anti-CPT1A, Internal
Artikelnummer: ARG64046.100
Protein function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Plays an important role in triglyceride metabolism. [The UniProt...
| Schlagworte: | Anti-CPT1, Anti-CPT1A, Anti-CPT I, Anti-CPTI-L, Anti-CPT1-L, EC=2.3.1.21, Anti-Carnitine palmitoyltransferase 1A,... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Human CPT1A / Carnitine O-palmitoyltransferase 1, liver...
Artikelnummer: G-HUFI00652.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-CPT1A
Artikelnummer: NSJ-R33564-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Carnitine palmitoyltransferase 1A Protein function: Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial...
| Schlagworte: | Anti-CPT1, Anti-CPT I, Anti-CPT1A, Anti-CPTI-L, Anti-CPT1-L, EC=2.3.1.21, Anti-Carnitine palmitoyltransferase 1A,... |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Anti-CPT1A
Artikelnummer: NSJ-F48084-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner membrane...
| Schlagworte: | Anti-CPT1, Anti-CPT I, Anti-CPT1A, Anti-CPTI-L, Anti-CPT1-L, EC=2.3.1.21, Anti-Carnitine palmitoyltransferase 1A,... |
| Anwendung: | IHC, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine |
ab 361,00 €
Palmitoyl-D-carnitine (chloride)
Artikelnummer: Cay26552-1
Palmitoyl-D-carnitine is a long-chain acylcarnitine, an isomer of palmitoyl-L-carnitine (Cay-26553), and the D enantiomer of palmitoyl-DL-carnitine (Cay-11095). It inhibits carnitine palmitoyltransferase with a Ki value of 2.1 mM for 14C-palmitoylcarnitine synthesis by erythrocyte membranes.Formal Name:...
| Schlagworte: | D-Hexadecanoylcarnitine, D-Palmitoylcarnitine, Hexadecanoyl-D-carnitine,... |
| Anwendung: | Carnitine palmitoyltransferase inhibitor |
| CAS | 28330-02-1 |
| MW: | 436.1 D |
ab 93,00 €
Anti-CPT1A / Carnitine O-palmitoyltransferase 1
Artikelnummer: NSJ-RQ6854
0.5mg/ml if reconstituted with 0.2ml sterile DI water. The mitochondrial oxidation of long-chain fatty acids is initiated by the sequential action of carnitine palmitoyltransferase I (which is located in the outer membrane and is detergent-labile) and carnitine palmitoyltransferase II (which is located in the inner...
| Schlagworte: | Anti-CPT1, Anti-CPT I, Anti-CPT1A, Anti-CPTI-L, Anti-CPT1-L, Anti-Carnitine palmitoyltransferase 1A, Anti-Carnitine... |
| Anwendung: | WB, IHC (paraffin), IF, FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
4-Hydroxyphenylglyoxylic Acid
Artikelnummer: Cay38121-10
4-Hydroxyphenylglyoxylic acid is an inhibitor of carnitine palmitoyltransferase 1 (CPT1) and an active metabolite of the prodrug oxfenicine (Cay-33698). It inhibits CPT1 in isolated rat liver mitochondria when used at concentrations ranging from 200 to 1,000 µM and inhibits oleate oxidation in isolated rat...
| Schlagworte: | UK 22486, 4-hydroxy-alpha-oxo-benzeneacetic acid |
| Anwendung: | Oxfenicine active metabolite, CPT1 inhibitor |
| CAS | 15573-67-8 |
| MW: | 166.1 D |
ab 60,00 €