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Zu "K08727" wurden 29 Artikel gefunden!
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Artikelnummer: TGM-T6591-100mg
Description: Nodinitib-1 (CID-1088438) is a potent and selective NOD1 inhibitor with an IC50 of 0.56 µM. Target: NOD, NOD-like Receptor (NLR), TNF. Smiles: Cc1ccc(cc1)S(=O)(=O)n1c(N)nc2ccccc12. References: Khan PM et al. ACS Med Chem Lett, 2011, 2(10), 780-785.
Schlagworte: | CID-1088438, ML130 |
Anwendung: | NOD1 inhibitor |
CAS | 799264-47-4 |
MW: | 287.34 D |
ab 49,00 €
Artikelnummer: TGM-T3587-100mg
Description: NOD-IN-1 (Compound 4) is a potent mixed inhibitor of nucleotide-binding oligomerization domain (NOD)-like receptors. Target: NOD-like Receptor (NLR), NOD. Smiles: CCOC(=O)c1cc2ccccc2n1S(=O)(=O)c1ccc(C)cc1. References: Kecek Plesec K, et al. Identification of indole scaffold-based dual inhibitors of...
Schlagworte: | Compound 4 |
Anwendung: | NOD1 / NOD2 inhibitor |
CAS | 132819-92-2 |
MW: | 343.4 D |
ab 67,00 €
Artikelnummer: CSB-PA047815.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NOD1. Antigen Species: Human
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: CSB-PA876477.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NOD1. Antigen Species: Human
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 167,00 €
Artikelnummer: Cay11040-5
NOD1 is a member of the NACHT and leucine-rich repeat domain-containing proteins (NLR) family of innate immunity proteins. It recognizes distinct molecular patterns from bacterial ligands and activates NF-kappaB, stress kinases, and interferon response factors important for host defense and inflammation. Hereditary...
Schlagworte: | CID-1088438, ML130, 1-[(4-methylphenyl)sulfonyl]-1H-benzimidazol-2-amine |
Anwendung: | NOD1 inhibitor |
CAS | 799264-47-4 |
MW: | 287.3 D |
ab 61,00 €
Artikelnummer: NSJ-R31707
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nucleotide-binding oligomerization domain-containing protein 1, also known as CARD4, is a protein receptor that in humans is encoded by the NOD1 gene. It is a member of NOD-like receptor protein family and is a close relative of Nod2. It recognizes bacterial...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | WB, IHC (paraffin), ICC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, rat |
772,00 €
Artikelnummer: NSJ-R33706-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nucleotide-binding oligomerization domain containing 1 Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | WB, ELISA (peptide) |
Wirt: | Goat |
Spezies-Reaktivität: | human |
790,00 €
Artikelnummer: E-AB-16300.120
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Artikelnummer: E-AB-13110.120
This gene encodes a member of the NOD (nucleotide-binding oligomerization domain) family. This member is a cytosolic protein. It contains an N-terminal caspase recruitment domain (CARD), a centrally located nucleotide-binding domain (NBD), and 10 tandem leucine-rich repeats (LRRs) in its C terminus. The CARD is...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | IHC, ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
ab 89,00 €
Artikelnummer: ARG59175.100
Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse |
616,00 €
Artikelnummer: ARG59215.50
Protein function: Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by...
Schlagworte: | Anti-NOD1, Anti-CARD4, Anti-Caspase recruitment domain-containing protein 4, Anti-Nucleotide-binding oligomerization... |
Anwendung: | ICC, IHC (paraffin) |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
551,00 €
Artikelnummer: Cay28370-1
NOD-IN-1 is an inhibitor of nucleotide-binding oligomerization domain (NOD) receptors and a derivative of nodinitib-1 (Cay-11040). NOD-IN-1 inhibits C12-iE-DAP-induced NF-?B activation in HEK-Blue cells expressing human recombinant NOD1 or NOD2 (IC50s = 5.74 and 6.45 µM, respectively).Formal Name:...
Schlagworte: | 1-[(4-methylphenyl)sulfonyl]-1H-indole-2-carboxylic acid, ethyl ester |
Anwendung: | NOD1 / NOD2 inhibitor |
CAS | 132819-92-2 |
MW: | 343.4 D |
ab 53,00 €