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Zu "K08653" wurden 28 Artikel gefunden!
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Artikelnummer: CSB-PA877556XA01DOA.100
Protein function: Serine protease that catalyzes the first step (site-1 cleavage) in the proteolytic activation of various factors, prior to site-2 cleavage. Part of a regulated intramembrane proteolysis (RIP) cascade. Cleaves BZIP17 and BZIP28 after the Arg-Arg-Ile-Leu (RRIL) motif. May cleave BZIP49 after the RRIL...
Schlagworte: | Anti-AtS1P, Anti-AtSBT6.1, Anti-Site-1 protease, Anti-Subtilase subfamily 6 member 1, Anti-Subtilisin-like protease... |
Anwendung: | ELISA, WB |
Spezies-Reaktivität: | Arabidopsis thaliana |
ab 147,00 €
Artikelnummer: TGM-T12437-100mg
Description: PF429242 dihydrochloride is a reversible and competitive inhibitor of S1P, with an IC50 of 175 nM. Target: S1P Receptor. Smiles: Cl.Cl.CCN(CC)Cc1ccc(cc1)C(=O)N(CCc1ccccc1OC)[C@@H]1CCNC1. References: Hawkins JL, et al. Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory...
Anwendung: | MBTPS1 inhibitor, antiviral |
CAS | 2248666-66-0 |
MW: | 482.49 D |
ab 37,00 €
Artikelnummer: TGM-TMPH-01661-100ug
Description: MBTPS1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.5 kDa and the accession number is Q14703.
Schlagworte: | MBTPS1, Endopeptidase S1P, Membrane-bound transcription factor site-1 protease, Subtilisin/kexin-isozyme 1 |
MW: | 37.5 kD |
ab 281,00 €
Artikelnummer: CSB-EP617930HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 218-414aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: DTGLSEKHPH FKNVKERTNW TNERTLDDGL GHGTFVAGVI ASMRECQGFA PDAELHIFRV FTNNQVSYTS WFLDAFNYAI LKKIDVLNLS IGGPDFMDHP FVDKVWELTA NNVIMVSAIG NDGPLYGTLN...
Schlagworte: | SKI-1, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, Membrane-bound transcription factor site-1 protease, Recombinant... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 37.5 kD |
ab 292,00 €
Artikelnummer: CSB-EP617930HU1.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 187-400aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: RAIPRQVAQT LQADVLWQMG YTGANVRVAV FDTGLSEKHP HFKNVKERTN WTNERTLDDG LGHGTFVAGV IASMRECQGF APDAELHIFR VFTNNQVSYT SWFLDAFNYA ILKKIDVLNL SIGGPDFMDH PFVDKVWELT...
Schlagworte: | SKI-1, Endopeptidase S1P, Subtilisin/kexin-isozyme 1, Membrane-bound transcription factor site-1 protease, Recombinant... |
Anwendung: | Activity not tested |
Exprimiert in: | E.coli |
Ursprungsart: | human |
MW: | 27.8 kD |
ab 292,00 €
Artikelnummer: CSB-MA617930A0m.100
Host Species: Mouse. Isotype: IgG1. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MBTPS1. Antigen Species: Human
Schlagworte: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
Anwendung: | ELISA, WB, FC |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 206,00 €
Artikelnummer: CSB-PA237035.100
Host Species: Rabbit. Isotype: IgG. Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by...
Schlagworte: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
Anwendung: | ELISA, WB |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
283,00 €
Artikelnummer: Cay15140-1
PF-429242 is an inhibitor of site-1 protease with an IC50 value of 170 nM for human recombinant site-1 protease. It is selective for site-1 protease over trypsin, elastase, proteinase K, plasmin, kallikren, factor XIa, thrombin, and furin at concentrations up to 100 µM. PF-429242 completely inhibits proteolytic...
Schlagworte: | 4-[(diethylamino)methyl]-N-[2-(2-methoxyphenyl)ethyl]-N-(3R)-3-pyrrolidinyl-benzamide, dihydrochloride |
Anwendung: | MBTPS1 inhibitor, antiviral |
CAS | 2248666-66-0 |
MW: | 482.5 D |
ab 69,00 €
Artikelnummer: ARG56137.100
Protein function: Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates...
Schlagworte: | Anti-SKI-1, Anti-MBTPS1, Anti-KIAA0091, EC=3.4.21.112, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1,... |
Anwendung: | WB, IHC (paraffin), ICC, IF |
Wirt: | Rabbit |
Spezies-Reaktivität: | human, mouse, rat |
658,00 €
Artikelnummer: ATA-HPA056109.100
Protein function: Serine protease that cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4: known substrates are SREBF1/SREBP1, SREBF2/SREBP2, BDNF, GNPTAB, ATF6 and ATF6B (PubMed:10644685, PubMed:12782636, PubMed:21719679). Cleaves substrates after Arg-Ser-Val-Leu (SREBP2),...
Schlagworte: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1 protease |
Anwendung: | IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 358,00 €

Artikelnummer: CSB-PA617930LA01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MBTPS1. Antigen Species: Human
Schlagworte: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
Anwendung: | ELISA, IHC |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 167,00 €

Artikelnummer: CSB-PA617930LB01HU.100
Host Species: Rabbit. Isotype: IgG. Buffer: Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: >95%, Protein G purified. Target Name: MBTPS1. Antigen Species: Human
Schlagworte: | Anti-SKI-1, Anti-Endopeptidase S1P, Anti-Subtilisin/kexin-isozyme 1, Anti-Membrane-bound transcription factor site-1... |
Anwendung: | ELISA |
Wirt: | Rabbit |
Spezies-Reaktivität: | human |
ab 167,00 €