Zu "K08558" wurden 26 Artikel gefunden!
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LY2452473
Artikelnummer: Cay43312-25
LY2452473 is an androgen receptor antagonist (IC50 = 8. nM).. Solulibility: DMSO: Soluble: =10 mg/ml: .
| Schlagworte: | TT 701, N-[(2S)-7-cyano-1,2,3,4-tetrahydro-4-(2-pyridinylmethyl)cyclopent[b]indol-2-yl]-carbamic acid, 1-methylethyl ester |
| Anwendung: | Androgen receptor antagonist |
| CAS | 1029692-15-6 |
| MW: | 374.44 D |
ab 109,00 €
NR4A2 Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01797-100ug
Description: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. NR4A2...
| Schlagworte: | Transcriptionally-inducible nuclear receptor, Immediate-early response protein NOT, Nuclear receptor subfamily 4 group A... |
| MW: | 68.6 kD |
ab 339,00 €
IP7e
Artikelnummer: TGM-T27620-100mg
Description: IP7e (isoxazolo-pyridinone 7e) is a Nurr1 activator with an EC50 value of 3.9 nM. Target: Others. Smiles: COCCOCc1ccc(cc1)-c1cc2onc(-c3ccccc3)c2c(=O)n1C. References: Montarolo F, et al. Effects of isoxazolo-pyridinone 7e, a potent activator of the Nurr1 signaling pathway, on experimental autoimmune...
| Schlagworte: | IP 7e, isoxazolo-pyridinone 7e, IP-7e |
| Anwendung: | Nurr1 signaling activator |
| CAS | 500164-74-9 |
| MW: | 390.43 D |
ab 117,00 €
C-DIM12
Artikelnummer: TGM-T3106-100mg
Description: C-DIM12 induced expression of Nurr1-regulated genes. C-DIM12 increased expression of transfected human Nurr1, induced Nurr1 protein expression in primary dopaminergic neurons and enhanced neuronal survival from exposure to 6-OHDA. Target: Apoptosis, Others. Smiles:...
| Anwendung: | Nurr1 / NR4A2 activator |
| CAS | 178946-89-9 |
| MW: | 356.85 D |
ab 31,00 €
Anti-NR4A2
Artikelnummer: CSB-PA449475.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NR4A2. Antigen Species: Human
| Schlagworte: | Anti-NOT, Anti-NR4A2, Anti-Orphan nuclear receptor NURR1, Anti-Immediate-early response protein NOT,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-NR4A2
Artikelnummer: CSB-PA949280.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: NR4A2. Antigen Species: Human
| Schlagworte: | Anti-NOT, Anti-NR4A2, Anti-Orphan nuclear receptor NURR1, Anti-Immediate-early response protein NOT,... |
| Anwendung: | ELISA, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Nuclear receptor subfamily 4 group A member 2 (NR4A2),...
Artikelnummer: CSB-YP016063HU.1
Organism: Homo sapiens (Human). Source: Yeast. Expression Region: 1-598aa. Protein Length: Full Length. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MPCVQAQYGS SPQGASPASQ SYSYHSSGEY SSDFLTPEFV KFSMDLTNTE ITATTSLPSF STFMDNYSTG YDVKPPCLYQ MPLSGQQSSI KVEDIQMHNY QQHSHLPPQS EEMMPHSGSV YYKPSSPPTP TTPGFQVQHS...
| Schlagworte: | NOT, NR4A2, Orphan nuclear receptor NURR1, Immediate-early response protein NOT, Transcriptionally-inducible nuclear... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Yeast |
| Ursprungsart: | human |
| MW: | 68.6 kD |
ab 347,00 €
4A7C-301-Nurr1 Agonist
Artikelnummer: Cay39453-1
4A7C-301-Nurr1 agonist is an agonist of nuclear receptor-related 1 (Nurr1). It binds to the Nurr1 ligand-binding domain (LBD, IC50 = 48.22 nM) and increases transcriptional activity of Nurr1-LBD and full-length Nurr1 in reporter assays using SK-N-BE(2)C human neuroblastoma cells (EC50s = 6.53 and 50-70 µM,...
| Schlagworte: | 4A7C-301-Nuclear Receptor-Related 1,... |
| Anwendung: | Nurr1 receptor agonist |
| MW: | 524.1 D |
ab 36,00 €
C-DIM12
Artikelnummer: Cay22951-10
C-DIM12 is a para-phenyl-substituted diindolylmethane (C-DIM) that is an orally bioavailable activator of nuclear receptor-related protein 1 (Nurr1/NR4A2). It is selective for Nurr1, not activating Nur77, neuron-derived orphan receptor 1 (Nor1), or the retinoid X receptor (RXR) in parallel luciferase assays. C-DIM12...
| Schlagworte: | 4-Chlorophenyl-3,3'-diindolylmethane, 3,3'-[(4-chlorophenyl)methylene]bis-1H-indole |
| Anwendung: | Nurr1 / NR4A2 activator |
| CAS | 178946-89-9 |
| MW: | 356.9 D |
ab 69,00 €
Anti-NURR1
Artikelnummer: NSJ-F49633-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Parkinson's disease (PD) is a multifactorial disease that appears to arise from the effects of both genetic and environmental influences. The known genetic factors include multiple genes that have been identified in related parkinsonian syndromes, as well as...
| Schlagworte: | Anti-NOT, Anti-NR4A2, Anti-Orphan nuclear receptor NURR1, Anti-Immediate-early response protein NOT,... |
| Anwendung: | IHC, IF, WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 350,00 €
IP7e
Artikelnummer: Cay29726-1
IP7e is a brain-penetrant activator of nuclear receptor related protein 1 (Nurr1/NR4A2) signaling (EC50 = 3.9 nM in a reporter assay). In vivo, IP7e (10 mg/kg) prevents spinal cord axonal loss and demyelination and decreases spinal cord macrophage and T cell infiltration in a mouse model of experimental autoimmune...
| Schlagworte: | Isoxazolo-pyridinone 7e, 6-[4-[(2-methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one |
| Anwendung: | Nurr1 signaling activator |
| CAS | 500164-74-9 |
| MW: | 390.4 D |
ab 111,00 €
Anti-NR4A2
Artikelnummer: ATA-HPA000543.100
Protein function: Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. [The...
| Schlagworte: | Anti-NOT, Anti-NR4A2, Anti-Orphan nuclear receptor NURR1, Anti-Immediate-early response protein NOT,... |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 320,00 €