Zu "K08555" wurden 59 Artikel gefunden!
Für die Filterung wurden keine Ergebnisse gefunden!
Spironolactone-d3
Artikelnummer: Cay40124-1
Spironolactone-d3 is intended for use as an internal standard for the quantification of spironolactone by GC- or LC-MS. Spironolactone is a steroidal mineralocorticoid receptor antagonist (IC50 = 24 nM) and a diuretic. It is selective for the mineralocorticoid receptor over the glucocorticoid receptor (IC50 = 2,410...
| Schlagworte: | S-((7R,8R,9S,10R,13S,14S,17R)-10,13-dimethyl-3,5'-dioxo-1,2,3,4',5',6,7,8,9,10,11,12,13,14,15,16-hexadecahydro-3'H-spiro[c... |
| Anwendung: | GC-MS, LC-MS internal standard, quantification, steroidal mineralocorticoid receptor antagonist |
| MW: | 419.6 D |
302,00 €
Rat MR (Mineralocorticoid Receptor) ELISA Kit
Artikelnummer: ELK-ELK3628.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat MR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat MR. Next, Avidin...
| Schlagworte: | MR, Mlr, Nr3c2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human MR (Mineralocorticoid Receptor) ELISA Kit
Artikelnummer: ELK-ELK4020.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MR. Next,...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Corticosterone
Artikelnummer: Cay16063-1
Corticosterone is a steroid hormone produced in the cortex of the adrenal glands that binds to both glucocorticoid and mineralocorticoid receptors. It is produced in response to ACTH (corticotropic hormone) and is the precursor to aldosterone synthesis. Since the production of glucocorticoids is increased by stress,...
| Schlagworte: | 11beta,21-DHP, 11beta,21-dihydroxy Progesterone, 17-deoxy Cortisol, NSC 9705, 11beta,21-dihydroxy-pregn-4-ene-3,20-dione |
| Anwendung: | Steroid hormone, Aldosterone precursor, Stress biomarker, Mineralocorticoid receptor agonist |
| CAS | 50-22-6 |
| MW: | 346.5 D |
ab 43,00 €
Eplerenone
Artikelnummer: Cay26302-1
Eplerenone (Cay-26302) is an analytical reference standard categorized as a diuretic. It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also available as a general research tool...
| Schlagworte: | (+)-Eplerenone, CGP 30083, Epoxymexrenone, SC-6110, SC-66110,... |
| Anwendung: | Analytical reference standard, Diuretic, Antihypertensive, Aldosterone antagonist |
| CAS | 107724-20-9 |
| MW: | 414.5 D |
ab 60,00 €
MR Bioassay for Environmental Sample Monitoring
Artikelnummer: IB-EM00501
This Mineralocorticoid Receptor Bioassay for Environmental Sample Monitoring kit is an all-inclusive luciferase reporter assay system that includes, in addition to MR Reporter Cells, two optimized media for use during cell culture and in diluting the user's test samples, the reference agonist Aldosterone, Luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
1.448,00 €
Aldosterone
Artikelnummer: Cay15273-500
Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance. Its primary role is to promote unidirectional salt reabsorption in epithelial tissues. Aldosterone is synthesized from cholesterol in the zona glomerulosa of the adrenal...
| Schlagworte: | 18-Aldocorticosterone, NSC 73856, Reichstein X, 11beta,21-dihydroxy-3,20-dioxo-pregn-4-en-18-al |
| Anwendung: | Steroid hormone, mineralocorticoid hormone |
| CAS | 52-39-1 |
| MW: | 360.4 D |
ab 43,00 €
![Aldosterone-[2,2,4,6,6,17,21,21-2H7]](https://www.biomol.com/media/image/5c/8a/39/ISO-S5093-100_200x200.png "Aldosterone-[2,2,4,6,6,17,21,21-2H7]")
Aldosterone-[2,2,4,6,6,17,21,21-2H7]
Artikelnummer: ISO-S5093.100
Isotope Incorporation: >98%
| Schlagworte: | Deuterium-labelled, CAS of labelled compound: 1261254-31-2, Aldosterone-[2,2,4,6,6,17,21,21-2H8] |
| Anwendung: | Mineralocorticoid receptor agonist, LC/MS internal standard |
| CAS | 52-39-1 |
680,00 €
11-deoxy Corticosterone
Artikelnummer: Cay22916-25
11-deoxy Corticosterone (DOC) is an endogenous mineralocorticoid synthesized in the zona fasciculata and zona glomerulosa of the adrenal gland. It is a metabolite of progesterone (Cay-15876) and precursor to aldosterone (Cay-15273) and corticosterone (Cay-16063). DOC is metabolized to the neuroactive compound...
| Schlagworte: | 21-hydroxy Progesterone, DOC, NSC 11319, 21-hydroxy-pregn-4-ene-3,20-dione |
| Anwendung: | Endogenous mineralocorticoid |
| CAS | 64-85-7 |
| MW: | 330.5 D |
ab 74,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00502
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
3.802,00 €
MR (human) Reporter Assay Kit
Artikelnummer: IB-IB00501-32
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive high-level expression of full-length, unmodified human mineralocorticoid receptor (NR3C2), a ligand-dependent transcription factor commonly referred to as MR. INDIGO's reporter cells include the luciferase...
| Schlagworte: | MR, MCR, NR3C2, Mineralocorticoid receptor, Nuclear receptor subfamily 3 group C member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
Eplerenone
Artikelnummer: LKT-E6245.10
Eplerenone displays antihypertensive, anti-inflammatory, and anti-angiogenic activities, it inhibits the mineralocorticoid receptor. Eplerenone inhibits aldosterone-induced expression of COX (therefore decreasing PGE2 levels), preventing the induction of COX and resulting kidney damage in high salt diets. This...
| Anwendung: | Mineralocorticoid receptor antagonist |
| CAS | 107724-20-9 |
| MW: | 414.29 D |
ab 189,00 €