Zu "K08551" wurden 216 Artikel gefunden!
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NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/6661
Artikelnummer: NSJ-V5880SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. Estrogen receptor 2 Antibody targets Estrogen receptor 2, a nuclear hormone receptor encoded by the ESR2 gene and widely known as estrogen receptor beta or ER beta. Estrogen receptor 2 functions as a ligand-activated transcriptional regulator that mediates cellular...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/9710
Artikelnummer: NSJ-V5882SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. ER beta antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 and ER beta in the literature. Estrogen receptor beta belongs to the steroid hormone receptor superfamily and functions as a...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/9709
Artikelnummer: NSJ-V5881SAF-100UG
1 mg/ml in 1X PBS, BSA free, sodium azide free. Estrogen receptor beta Antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 in the literature. ER beta functions as a ligand-activated transcriptional regulator that modulates cellular...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
810,00 €
NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/6661
Artikelnummer: NSJ-V5880-100UG
0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Estrogen receptor 2 Antibody targets Estrogen receptor 2, a nuclear hormone receptor encoded by the ESR2 gene and widely known as estrogen receptor beta or ER beta. Estrogen receptor 2 functions as a ligand-activated transcriptional regulator that mediates...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/9710
Artikelnummer: NSJ-V5882-100UG
0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. ER beta antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 and ER beta in the literature. Estrogen receptor beta belongs to the steroid hormone receptor superfamily and...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
NEU
Anti-ESR2 / Estrogen Receptor beta, clone ESR2/9709
Artikelnummer: NSJ-V5881-100UG
0.2 mg/ml in 1X PBS with 0.05% BSA, 0.05% sodium azide. Estrogen receptor beta Antibody targets Estrogen receptor beta, a nuclear hormone receptor encoded by the ESR2 gene and also referred to as Estrogen receptor 2 in the literature. ER beta functions as a ligand-activated transcriptional regulator that modulates...
| Schlagworte: | Anti-ESR2, Anti-Estrogen receptor beta, Anti-Nuclear receptor subfamily 3 group A member 2, ESR2 Antibody / Estrogen... |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 375,00 €
Tamoxifen
Artikelnummer: Cay13258-5
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
| Schlagworte: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
| Anwendung: | Estrogen receptor modulator |
| CAS | 10540-29-1 |
| MW: | 371.5 D |
ab 101,00 €
(E/Z)-4-hydroxy Tamoxifen
Artikelnummer: Cay17308-50
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
| Schlagworte: | 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
| Anwendung: | Active tamoxifen metabolite, estrogen receptor agonist/antagonist |
| CAS | 68392-35-8 |
| MW: | 387.5 D |
ab 59,00 €
Tamoxifen (citrate)
Artikelnummer: Cay11629-5
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
| Schlagworte: | ICI 46474, Istubal, Kessar, Noltam, Nolvadex, TMX, Valodex, Zemide,... |
| Anwendung: | Estrogen receptor (ER) modulator, Apoptosis inducer |
| CAS | 54965-24-1 |
| MW: | 563.6 D |
ab 69,00 €
Tamoxifen
Artikelnummer: CDX-T0200-G005
Synthetic. Chemical. CAS: 10540-29-1. Formula: C26H29NO. MW: 371.51. Synthetic. Selective estrogen receptor modulator (SERM) used as adjuvant therapy for estrogen-dependent breast cancer. Antagonist of ER action in breast tissue and breast cancer cells and ER agonist in bone, uterus, and the cardiovasculature...
| Schlagworte: | (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine |
| Anwendung: | Selective estrogen receptor modulator |
| CAS | 10540-29-1 |
| MW: | 371,51 D |
ab 77,00 €
Erteberel
Artikelnummer: Cay22130-1
Erteberel is an estrogen receptor beta (ERbeta) agonist. It is selective for ERbeta over ERalpha in reporter assays using PC3 cells expressing the human receptors (EC50s = 0.66 and 19.4 nM, respectively). Ertebrel (5 µM) induces apoptosis and cell cycle arrest at the G2/M phase in U87MG and U251 glioblastoma cells....
| Schlagworte: | LY500307, (3aS,4R,9bR)-1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-cyclopenta[c][1]benzopyran-8-ol |
| Anwendung: | Estrogen receptor beta agonist |
| CAS | 533884-09-2 |
| MW: | 282.3 D |
ab 112,00 €
Bazedoxifene (acetate)
Artikelnummer: Cay15005-5
Bazedoxifene (acetate) is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERalpha (IC50 = 26 nM) and ERbeta (IC50 = 99 nM). Bazedoxifene (actetate) antagonizes 17beta-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as...
| Schlagworte: | TSE 424, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, acetate |
| Anwendung: | Selective estrogen receptor modulator |
| CAS | 198481-33-3 |
| MW: | 530.7 D |
ab 172,00 €