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Zu "K08551" wurden 172 Artikel gefunden!
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Artikelnummer: Cay38954-100
Dienestrol is a synthetic non-steroidal estrogen receptor (ER) agonist and an active metabolite of diethylstilbestrol (Cay-10006876). Dienestrol binds to ERalpha and ERbeta (Kis = 0.05 and 0.03 nM, respectively) and activates ERalpha in a reporter assay (EC50 = 3.23 nM). It also inhibits porcine microtubule assembly...
Schlagworte: | Dienoestrol, NSC 59809, 4,4'-(1,2-diethylidene-1,2-ethanediyl)bis-phenol |
Anwendung: | Diethylstilbestrol active metabolite, synthetic non-steroidal estrogen receptor agonist |
CAS | 84-17-3 |
MW: | 266.3 D |
ab 93,00 €
Artikelnummer: Cay13258-5
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
Schlagworte: | 2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-ethanamine |
Anwendung: | Estrogen receptor modulator |
CAS | 10540-29-1 |
MW: | 371.5 D |
ab 77,00 €
Artikelnummer: ELK-ELK2931.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat ERb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat ERb. Next, Avidin...
Schlagworte: | Esr2, Erbeta, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
Anwendung: | ELISA |
Spezies-Reaktivität: | rat |
ab 365,00 €
Artikelnummer: ELK-ELK2983.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human ERb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human ERb. Next,...
Schlagworte: | ESR2, ESTRB, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: ELK-ELK4281.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse ERb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse ERb. Next,...
Schlagworte: | Esr2, Estrb, ER-beta, Estrogen receptor beta, Nuclear receptor subfamily 3 group A member 2 |
Anwendung: | ELISA |
Spezies-Reaktivität: | mouse |
ab 365,00 €
Artikelnummer: Cay17308-50
(E/Z)-4-hydroxy Tamoxifen is an active metabolite of tamoxifen (Cay-13258). It is formed from tamoxifen by the cytochrome P450 (CYP) isoform CYP2D6. (E/Z)-4-hydroxy Tamoxifen is cytotoxic to MCF-7 and MDA-MB-231 breast cancer cells (IC50s = 27 and 18 µM, respectively). It also stimulates LC3 lipidation and the...
Schlagworte: | 4-hydroxy Tamoxifen, 4-OHT, Afimoxifene, 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-phenol |
Anwendung: | Active tamoxifen metabolite, estrogen receptor agonist/antagonist |
CAS | 68392-35-8 |
MW: | 387.5 D |
ab 43,00 €
Artikelnummer: Cay11629-5
Tamoxifen is an estrogen receptor antagonist (IC50 = 45 nM for the rabbit receptor). It reduces the proliferation of MCF-7 breast cancer cells when used at a concentration of 10 µM. Tamoxifen is active against S. cerevisiae, C. neoformans, and five Candida species (MICs = 12, 64, and 8-64 µg/ml, respectively). It...
Schlagworte: | ICI 46474, Istubal, Kessar, Noltam, Nolvadex, TMX, Valodex, Zemide,... |
Anwendung: | Estrogen receptor (ER) modulator, Apoptosis inducer |
CAS | 54965-24-1 |
MW: | 563.6 D |
ab 56,00 €
Artikelnummer: Cay22130-1
Erteberel is an estrogen receptor beta (ERbeta) agonist. It is selective for ERbeta over ERalpha in reporter assays using PC3 cells expressing the human receptors (EC50s = 0.66 and 19.4 nM, respectively). Ertebrel (5 µM) induces apoptosis and cell cycle arrest at the G2/M phase in U87MG and U251 glioblastoma cells....
Schlagworte: | LY500307, (3aS,4R,9bR)-1,2,3,3a,4,9b-hexahydro-4-(4-hydroxyphenyl)-cyclopenta[c][1]benzopyran-8-ol |
Anwendung: | Estrogen receptor beta agonist |
CAS | 533884-09-2 |
MW: | 282.3 D |
ab 97,00 €
Artikelnummer: Cay15005-5
Bazedoxifene (acetate) is a third generation selective estrogen receptor modulator (SERM). It is an indole-based ER ligand that binds to both ERalpha (IC50 = 26 nM) and ERbeta (IC50 = 99 nM). Bazedoxifene (actetate) antagonizes 17beta-estradiol-dependent MCF-7 and T47D breast cancer cell proliferation in vitro as...
Schlagworte: | TSE 424, 1-[[4-[2-(hexahydro-1H-azepin-1-yl)ethoxy]phenyl]methyl]-2-(4-hydroxyphenyl)-3-methyl-1H-indol-5-ol, acetate |
Anwendung: | Selective estrogen receptor modulator |
CAS | 198481-33-3 |
MW: | 530.7 D |
ab 149,00 €
Artikelnummer: CDX-T0200-G005
Synthetic. Chemical. CAS: 10540-29-1. Formula: C26H29NO. MW: 371.51. Synthetic. Selective estrogen receptor modulator (SERM) used as adjuvant therapy for estrogen-dependent breast cancer. Antagonist of ER action in breast tissue and breast cancer cells and ER agonist in bone, uterus, and the cardiovasculature...
Schlagworte: | (Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene, trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine |
Anwendung: | Selective estrogen receptor modulator |
CAS | 10540-29-1 |
MW: | 371,51 D |
ab 77,00 €
Artikelnummer: Cay13184-10
Equol is a nonsteroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora. The estrogen receptor (ER) binding activity of the naturally occurring (S)-enantiomer demonstrates greater affinity toward ERbeta while the (R)-enantiomer demonstrates greater...
Schlagworte: | 3,4-dihydro-3-(4-hydroxyphenyl)-2H-1-benzopyran-7-ol |
Anwendung: | Estrogen receptor agonist |
CAS | 94105-90-5 |
MW: | 242.3 D |
ab 44,00 €
Artikelnummer: Cay27189-25
Raloxifene (hydrochloride) (Cay-27189) is an analytical reference standard categorized as a selective estrogen receptor modulator (SERM). It has been detected as an adverse analytical finding (AAF) during anti-doping testing. This product is intended for use in analytical forensic applications. This product is also...
Schlagworte: | Keoxifene, LY156758, [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-[2-(1-piperidinyl)ethoxy]phenyl]-methanone,... |
Anwendung: | Analytical reference standard, Selective estrogen receptor modulator (SERM) |
CAS | 82640-04-8 |
MW: | 510 D |
ab 147,00 €