Zu "K08540" wurden 43 Artikel gefunden!
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Anti-NR1I2 / PXR
Artikelnummer: NSJ-RQ5593
0.5mg/ml if reconstituted with 0.2ml sterile DI water. In the field of molecular biology, the pregnane X receptor (PXR), also known as the steroid and xenobiotic sensing nuclear receptor (SXR) or nuclear receptor subfamily 1, group I, member 2 (NR1I2) is a protein that in humans is encoded by the NR1I2 (nuclear...
| Schlagworte: | Anti-PXR, Anti-SXR, Anti-NR1I2, Anti-Pregnane X receptor, Anti-Orphan nuclear receptor PXR, Anti-Orphan nuclear receptor... |
| Anwendung: | WB, IHC (paraffin), FC, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
Rat PXR (Pregnane X Receptor) ELISA Kit
Artikelnummer: ELK-ELK6436.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat PXR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat PXR. Next, Avidin...
| Schlagworte: | Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Human PXR (Pregnane X Receptor) ELISA Kit
Artikelnummer: ELK-ELK3247.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PXR. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PXR. Next,...
| Schlagworte: | SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
12-keto Lithocholic Acid
Artikelnummer: Cay29547-5
12-keto Lithocholic acid is a metabolite of the secondary bile acid deoxycholic acid (DCA, Cay-20756, Cay-18231). Fecal levels of 12-keto lithocholic acid are elevated in rats fed a diet supplemented with cholic acid (Cay-20250) or DCA compared with rats fed a control diet or a diet supplemented with cholesterol...
| Schlagworte: | 12-keto-LCA, 12-Oxolithocholic Acid, (3alpha,5beta)-3-hydroxy-12-oxo-cholan-24-oic acid |
| Anwendung: | DCA metabolite, Human pregnane X receptor agonist |
| CAS | 5130-29-0 |
| MW: | 390.6 D |
ab 105,00 €
Pregnenolone Carbonitrile
Artikelnummer: Cay16343-25
Pregnenolone carbonitrile (PCN) is a catatoxic steroid that acts as an agonist of the rodent pregnane X receptor (PXR) at µM concentrations. It has been shown to mediate induction of hepatic cytochrome P450 3A, organic anion transporting peptide-2, and cholesterol 7alpha-hydroxylase, regulating both xenobiotic and...
| Schlagworte: | PCN, Pregnenolone 16alpha-carbonitrile, SC-4674, 3beta-hydroxy-20-oxo-pregn-5-ene-16alpha-carbonitrile |
| Anwendung: | Rodent pregnane X receptor (PXR) agonist |
| CAS | 1434-54-4 |
| MW: | 341.5 D |
ab 54,00 €
PXR (human) Reporter Assay Kit
Artikelnummer: IB-IB07001-32
Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the...
| Schlagworte: | SXR, PXR, NR1I2, Pregnane X receptor, Orphan nuclear receptor PXR, Orphan nuclear receptor PAR1, Steroid and xenobiotic... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.448,00 €
Trabectedin
Artikelnummer: Cay34662-1
Trabectedin is an alkaloid that has been found in E. turbinata and has anticancer activity. It is a guanine-specific DNA alkylating agent and an antagonist of the pregnane X receptor (PXR, IC50 = ~3 nM in a reporter assay). Trabectedin reduces viability of DU145 and PC3 human prostate cancer stem cells in a...
| Schlagworte: | Ecteinascidin 743, ET-743, NSC 648766,... |
| Anwendung: | Alkaloid, Anticancer agent, PXT antagonist, Guanine-specific DNA alkylating agent |
| CAS | 114899-77-3 |
| MW: | 761.8 D |
ab 259,00 €
Anti-PXR, Internal
Artikelnummer: ARG64848.100
Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, drugs and endogenous compounds. Activated by the...
| Schlagworte: | Anti-PXR, Anti-SXR, Anti-NR1I2, Anti-Pregnane X receptor, Anti-Orphan nuclear receptor PXR, Anti-Orphan nuclear receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
784,00 €
Human PXR / NR1I2 ELISA Kit
Artikelnummer: G-HUFI00939.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
641,00 €
Mouse PXR / NR1I2 ELISA Kit
Artikelnummer: G-MOFI00332.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
694,00 €
Anti-NR1I2
Artikelnummer: NSJ-R33931-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Nuclear receptor subfamily 1, group I, member 2 Protein function: Nuclear receptor that binds and is activated by variety of endogenous and xenobiotic compounds. Transcription factor that...
| Schlagworte: | Anti-PXR, Anti-SXR, Anti-NR1I2, Anti-Pregnane X receptor, Anti-Orphan nuclear receptor PXR, Anti-Orphan nuclear receptor... |
| Anwendung: | WB, IHC (paraffin), ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
755,00 €
PXR (Rat) Reporter Assay System
Artikelnummer: IB-R07001
Protein function: Nuclear receptor that binds and is activated by a variety of endogenous and xenobiotic compounds. Transcription factor that activates the transcription of multiple genes involved in the metabolism and secretion of potentially harmful xenobiotics, endogenous compounds and drugs. Response to specific...
| Schlagworte: | Pxr, Nr1i2, Pregnane X receptor, Orphan nuclear receptor PXR, Nuclear receptor subfamily 1 group I member 2 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | rat |
ab 1.448,00 €