Zu "K08536" wurden 53 Artikel gefunden!

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Mouse LXRa (Liver X Receptor Alpha) ELISA Kit
Mouse LXRa (Liver X Receptor Alpha) ELISA Kit

Artikelnummer: ELK-ELK6666.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse LXRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse LXRa. Next,...
Schlagworte: Lxra, Nr1h3, Liver X receptor alpha, Oxysterols receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3
Anwendung: ELISA
Spezies-Reaktivität: mouse
365,00 € ab 328,50 €
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Human LXRa (Liver X Receptor Alpha) ELISA Kit
Human LXRa (Liver X Receptor Alpha) ELISA Kit

Artikelnummer: ELK-ELK2764.48

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human LXRa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human LXRa. Next,...
Schlagworte: LXRA, NR1H3, Liver X receptor alpha, Oxysterols receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3
Anwendung: ELISA
Spezies-Reaktivität: human
365,00 € ab 328,50 €
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LXRa Reporter Assay System (dog)
LXRa Reporter Assay System (dog)

Artikelnummer: IB-D00311

Schlagworte: Nuclear receptor subfamily 1 group H member 3
Anwendung: Functional activity screening
Spezies-Reaktivität: dog
1.448,00 €
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GW 3965 (hydrochloride)
GW 3965 (hydrochloride)

Artikelnummer: Cay10054-1

The liver X receptors, LXRalpha and LXRbeta, are nuclear receptors that act as ligand-dependent transcription factors. They modulate cholesterol, fatty acids, and glucose homeostasis. GW 3965 is an orally-active agonist of LXRalpha and LXRbeta, activating the human isoforms with EC50 values of 190 and 30 nM,...
Schlagworte: 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-benzeneacetic acid, monohydrochloride
Anwendung: LXR alpha / beta agonist
CAS 405911-17-3
MW: 618.5 D
ab 53,00 €
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25(S)-27-hydroxy Cholesterol
25(S)-27-hydroxy Cholesterol

Artikelnummer: Cay14791-1

The liver x receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
Schlagworte: (25S)-26-hydroxy cholesterol, (25S)-cholest-5-ene-3beta,26-diol
Anwendung: LXR alpha / beta activator
CAS 56845-83-1
MW: 402.7 D
ab 77,00 €
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T0901317
T0901317

Artikelnummer: Cay71810-50

The Liver X Receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7alpha-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and...
Schlagworte: N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide
Anwendung: LXRalpha agonist, LXRbeta agonist
CAS 293754-55-9
MW: 481.3 D
ab 54,00 €
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SR9238
SR9238

Artikelnummer: Cay18771-1

The liver X receptors (LXRs) are nuclear receptors that act as ligand-dependent transcription factors. They modulate lipid, cholesterol, and carbohydrate metabolism and homeostasis. SR9238 is an inverse agonist of the two LXR isoforms, LXRalpha and LXRbeta (IC50s = 214 and 43 nM, respectively). It displays liver...
Schlagworte: 5-[[[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl][(2,4,6-trimethylphenyl)sulfonyl]amino]methyl]-2-furancarboxylic...
Anwendung: LXRA / LXRB inverse agonist
CAS 1416153-62-2
MW: 595.7 D
ab 44,00 €
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25(R)-27-hydroxy Cholesterol
25(R)-27-hydroxy Cholesterol

Artikelnummer: Cay14790-5

The liver X receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
Schlagworte: (25R)-26-hydroxy Cholesterol, (25R)-cholest-5-ene-3beta,26-diol
Anwendung: LXR alpha / beta activator
CAS 20380-11-4
MW: 402.7 D
ab 77,00 €
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24(R)-hydroxy Cholesterol
24(R)-hydroxy Cholesterol

Artikelnummer: Cay10217-1

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that is generated from the action of CYP46 on cholesterol found in the brain and plays an important role in cholesterol homeostasis. 24(R)-hydroxy Cholesterol is a synthetic enantiomer of 24(S)-hydroxy cholesterol that activates LXRalpha and LXRbeta...
Schlagworte: 24-Epicerebrosterol, cholest-5-ene-3beta,24R-diol
Anwendung: LXR alpha / beta agonist
CAS 27460-26-0
MW: 402.7 D
ab 66,00 €
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GSK2033
GSK2033

Artikelnummer: Cay25443-1

GSK2033 is an antagonist of liver X receptor alpha (LXRalpha) and LXRbeta (IC50s = 0.1 and 0.398 µM, respectively) that has no agonist activity in an LXR transactivation assay. It inhibits LXR agonist-induced and basal expression of the LXR target genes ATP-binding cassette transporter 1 (ABCA1) and sterol...
Schlagworte: 2,4,6-trimethyl-N-[[3'-(methylsulfonyl)[1,1'-biphenyl]-4-yl]methyl]-N-[[5-(trifluoromethyl)-2-furanyl]methyl]-benzenesulfo...
Anwendung: LXRalpha / LXRbeta antagonist
CAS 1221277-90-2
MW: 591.7 D
ab 43,00 €
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24(S)-hydroxy Cholesterol
24(S)-hydroxy Cholesterol

Artikelnummer: Cay10009931-5

24(S)-hydroxy Cholesterol is a side-chain substituted oxysterol that has important roles in cholesterol homeostasis. It is generated by the action of CYP46 on cholesterol in the brain and diffuses across the blood-brain barrier to the systemic circulation where it can modulate cell signaling, be used for further...
Schlagworte: Cerebrosterol, cholest-5-ene-3beta,24S-diol
Anwendung: LXR alpha / beta agonist
CAS 474-73-7
MW: 402.7 D
ab 92,00 €
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LXR-623
LXR-623

Artikelnummer: Cay21117-1

LXR-623 is a liver X receptor (LXR) modulator that acts as a partial agonist at LXRalpha and a full agonist at LXRbeta (IC50s = 179 and 24 nM, respectively). It is orally bioavailable and readily passes the blood-brain barrier. LXR-623 is anti-atherogenic in animal models of atherosclerosis, showing synergistic...
Schlagworte: WAY-252623, 2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophenyl)-7-(trifluoromethyl)-2H-indazole
Anwendung: LXR agonist
CAS 875787-07-8
MW: 422.8 D
ab 43,00 €
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