Zu "K08532" wurden 37 Artikel gefunden!
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SR 3335
Artikelnummer: Cay12072-25
The retinoic acid receptor-related receptors (RORs) are orphan nuclear receptors with diverse putative roles. SR 3335 is a selective inverse agonist of RORalpha, competitively inhibiting the binding of 25-hydroxycholesterol to the ligand binding domain (Ki = 220 nM) and inhibiting constitutive transactivation...
| Schlagworte: | ML 176, N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-2-thiophenesulfonamide |
| Anwendung: | RORalpha agonist |
| CAS | 293753-05-6 |
| MW: | 405.3 D |
ab 49,00 €
RORa (Human) Reporter Assay System
Artikelnummer: IB-IB04011
Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid,...
| Schlagworte: | RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related... |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
Neoruscogenin
Artikelnummer: Cay15567-5
Neoruscogenin is a natural sapogenin isolated from Butcher's broom (R. rhizoma), which is traditionally used against chronic venous disorders. It is a bioavailable, potent, and high-affinity agonist of the nuclear receptor RORalpha (EC50 = 110 nM). In mice, neoruscogenin up-regulates the expression of several...
| Schlagworte: | 25(27)-Dehydroruscogenin, spirosta-5,25(27)-diene-1beta,3beta-diol |
| Anwendung: | RORalpha agonist |
| CAS | 17676-33-4 |
| MW: | 428.6 D |
ab 178,00 €
SR 1078
Artikelnummer: Cay16503-1
Retinoic acid receptor-related orphan receptors alpha and gamma (RORalpha and RORgamma) have been demonstrated to play important roles in the regulation of metabolism, circadian rhythms, immune function, and tumorigenesis. SR 1078 is a selective agonist of RORalpha and RORgamma that stimulates ROR transcriptional...
| Schlagworte: | N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)-benzamide |
| Anwendung: | ROR alpha / beta agonist |
| CAS | 1246525-60-9 |
| MW: | 431.3 D |
ab 49,00 €
Anti-RORA
Artikelnummer: E-AB-13577.120
The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside...
| Schlagworte: | Anti-RORA, Anti-NR1F1, Anti-Nuclear receptor RZR-alpha, Anti-Nuclear receptor ROR-alpha, Anti-RAR-related orphan receptor... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-RORA
Artikelnummer: ARG58393.100
Protein function: Nuclear receptor that binds DNA as a monomer to ROR response elements (RORE) containing a single core motif half-site 5'-AGGTCA-3' preceded by a short A-T-rich sequence. Key regulator of embryonic development, cellular differentiation, immunity, circadian rhythm as well as lipid, steroid,...
| Schlagworte: | Anti-RORA, Anti-NR1F1, Anti-Nuclear receptor ROR-alpha, Anti-Nuclear receptor RZR-alpha, Anti-RAR-related orphan receptor... |
| Anwendung: | ICC, IF, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
Human RORa (RAR Related Orphan Receptor Alpha) ELISA Kit
Artikelnummer: ELK-ELK5292.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RORa. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RORa. Next,...
| Schlagworte: | RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Nuclear receptor ROR-alpha (RORA), human, recombinant
Artikelnummer: CSB-BP020069HU.1
Organism: Homo sapiens (Human). Source: Baculovirus. Expression Region: 1-468aa. Protein Length: Full Length of Isoform 4. Tag Info: N-terminal 10xHis-tagged and C-terminal Myc-tagged. Target Protein Sequence: MMYFVIAAMK SQIEIIPCKI CGDKSSGIHY GVITCEGCKG FFRRSQQSNA TYSCPRQKNC LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF...
| Schlagworte: | RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related... |
| Anwendung: | Activity not tested |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
| MW: | 57.4 kD |
ab 489,00 €
Nuclear receptor ROR-alpha (RORA), human, recombinant
Artikelnummer: CSB-EP020069HUa0.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-468aa. Protein Length: Full Length of Isoform 4. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: MMYFVIAAMK SQIEIIPCKI CGDKSSGIHY GVITCEGCKG FFRRSQQSNA TYSCPRQKNC LIDRTSRNRC QHCRLQKCLA VGMSRDAVKF GRMSKKQRDS LYAEVQKHRM QQQQRDHQQQ...
| Schlagworte: | RORA, NR1F1, Nuclear receptor ROR-alpha, Nuclear receptor RZR-alpha, RAR-related orphan receptor A, Retinoid-related... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 57.6 kD |
ab 292,00 €
Anti-RORA
Artikelnummer: CSB-PA004020.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-RORA, Anti-NR1F1, Anti-Nuclear receptor ROR-alpha, Anti-Nuclear receptor RZR-alpha, Anti-RAR-related orphan receptor... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, monkey |
ab 126,00 €
Anti-RORA
Artikelnummer: CSB-PA182231.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RORA. Antigen Species: Human
| Schlagworte: | Anti-RORA, Anti-NR1F1, Anti-Nuclear receptor ROR-alpha, Anti-Nuclear receptor RZR-alpha, Anti-RAR-related orphan receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 167,00 €
Neoruscogenin
Artikelnummer: TGM-T3S1251-100mg
Description: 1. Neoruscogenin represents a universal pharmacological tool for RORalpha research due to its specific selectivity profile versus other nuclear receptors. Target: ROR. Smiles: [H][C@]12C[C@@]3([H])[C@]4([H])CC=C5C[C@@H](O)C[C@@H](O)[C@]5(C)[C@@]4([H])CC[C@]3(C)[C@@]1([H])[C@H](C)[C@@]1(CCC(=C)CO1)O2....
| Anwendung: | RORalpha agonist |
| CAS | 17676-33-4 |
| MW: | 428.6 D |
ab 56,00 €