Zu "K08530" wurden 229 Artikel gefunden!
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Rosiglitazone
Artikelnummer: Cay71740-10
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
| Schlagworte: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 122320-73-4 |
| MW: | 357.4 D |
ab 53,00 €
NEU
PPARgamma LBD (human, recombinant)
Artikelnummer: Cay10007941-100
PPARgamma is a ligand-activated transcription factor and member of the nuclear hormone receptor superfamily. It is composed of an N-terminal AF1 domain responsible for ligand-independent transactivation, a DNA-binding domain (DBD), a hinge region, and a C-terminal ligand-binding domain (LBD) and AF2 domain. It is...
| Schlagworte: | NR1C3, Nuclear Receptor Subfamily 1 Group C Member 3, Peroxisome Proliferator-activated Receptor gamma Ligand-binding... |
| Anwendung: | Ligand binding studies |
| Exprimiert in: | E.coli |
| MW: | 34 kD |
671,00 €
GW 9662
Artikelnummer: Cay70785-10
The peroxisome proliferator-activated receptor gamma (PPARgamma) is the nuclear receptor responsible for transducing the therapeutic activity of the thiazolidinediones. Thiazolidinediones are a group of structurally related synthetic PPARgamma agonists with antidiabetic actions in vivo. Rosiglitazone (BRL 49653) is...
| Schlagworte: | 2-chloro-5-nitrobenzanilide |
| Anwendung: | Irreversible PPARgamma antagonist |
| CAS | 22978-25-2 |
| MW: | 276.7 D |
ab 38,00 €
Anti-Recombinant PPAR-gamma, clone 11A10
Artikelnummer: E-AN301397L.100
PPARG(peroxisome proliferator activated receptor gamma) Homo sapiens This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three...
| Schlagworte: | Anti-PPARG, Anti-Nuclear receptor subfamily 1 group C member 3, Anti-Peroxisome proliferator-activated receptor gamma,... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
391,00 €
Anti-PPAR gamma / PPARG, clone 31P97
Artikelnummer: NSJ-FY12851
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. PPAR gamma antibody targets peroxisome proliferator activated receptor gamma, a nuclear receptor encoded by the PPARG gene. PPAR gamma functions as a ligand activated transcription factor and plays...
| Schlagworte: | Anti-PPARG, Anti-Nuclear receptor subfamily 1 group C member 3, Anti-Peroxisome proliferator-activated receptor gamma,... |
| Anwendung: | WB, ICC, IF, FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-Zebrafish Ppar gamma / Pparg
Artikelnummer: NSJ-RZ1276
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Pparg (Peroxisome proliferator-activated receptor gamma) is a critical transcription factor that belongs to the nuclear receptor superfamily. It plays a vital role in regulating lipid metabolism, glucose homeostasis, inflammation, and adipocyte differentiation....
| Schlagworte: | Anti-pparg, Anti-Nuclear receptor subfamily 1 group C member 3, Anti-Peroxisome proliferator-activated receptor gamma,... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Troglitazone
Artikelnummer: Cay71750-5
Troglitazone is a selective agonist of peroxisome proliferator-activated receptor gamma (PPARgamma, EC50s = 0.78 and 0.55 µM for the mouse and human receptors, respectively, in a transactivation assay). It is selective for PPARgamma over PPARalpha and PPARdelta, at which it is inactive at concentrations up to 10 µM....
| Schlagworte: | 5-[[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 97322-87-7 |
| MW: | 441.5 D |
ab 89,00 €
15-deoxy-Delta12,14-Prostaglandin J2
Artikelnummer: Cay18570.1-1
This formulation of 15-deoxy-Delta12,14-PGJ2 contains 90-95% of the trans,trans-Delta12,14 isomer, and 5-10% of other double bond isomers which have similar PPARgamma ligand activity (see Catalog No. 18570).Formal Name: 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid. CAS Number: 87893-55-8. Synonyms:...
| Schlagworte: | 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid |
| Anwendung: | PPARgamma ligand |
| CAS | 87893-55-8 |
| MW: | 316.4 D |
ab 110,00 €
PPARgamma Transcription Factor Assay Kit
Artikelnummer: Cay10006855-96
Peroxisome proliferator-activated receptors (PPARs) are ligand-activated transcription factors belonging to the large family of nuclear hormone receptors. There are three subtypes, PPARalpha, beta/delta, and gamma, which are expressed at variable levels in different tissues. The Cayman Chemical PPARgamma...
| Schlagworte: | Peroxisome Proliferator-activated Receptor gamma Transcription Factor Assay Kit |
| Anwendung: | PPARgamma binding detection |
| Spezies-Reaktivität: | human |
732,00 €
PPARgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00101
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human peroxisome proliferator-activated receptor gamma (NR1C3), a ligand-dependent transcription factor commonly referred to as PPARG or PPARgamma. INDIGO's reporter cells include...
| Schlagworte: | NR1C3, PPARG, PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Peroxisome proliferator-activated receptor gamma |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
Rosiglitazone
Artikelnummer: AG-CR1-3570-M010
Antidiabetic, hypoglycemic agent. Potent and selective peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist. Potent insulin sensitizing agent binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. Ameliorates insulin resistance. Improves blood pressure and...
| Schlagworte: | BRL 49653, HSDB 7555, TDZ 01 |
| Anwendung: | PPAR-gamma agonist |
| Wirt: | Synthetic |
| CAS | 122320-73-4 |
| MW: | 357,4 D |
ab 33,00 €
Rosiglitazone (potassium salt)
Artikelnummer: Cay71742-100
Rosiglitazone is an agonist of peroxisome proliferator-activated receptor gamma (PPARgamma). It activates PPARgamma1 and PPARgamma2 in reporter assays (EC50s = 30 and 100 nM, respectively). Rosiglitazone selectively activates chimeras containing the ligand-binding domains (LBDs) of PPARgamma over PPARalpha and...
| Schlagworte: | 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione, monopotassium salt |
| Anwendung: | PPARgamma agonist |
| CAS | 316371-84-3 |
| MW: | 395.5 D |
ab 49,00 €