- Suchergebnis für K08529
Cookie-Einstellungen
Diese Website benutzt Cookies, die für den technischen Betrieb der Website erforderlich sind und stets gesetzt werden. Andere Cookies, die den Komfort bei Benutzung dieser Website erhöhen, der Direktwerbung dienen oder die Interaktion mit anderen Websites und sozialen Netzwerken vereinfachen sollen, werden nur mit Ihrer Zustimmung gesetzt.
Konfiguration
Technisch erforderlich
Diese Cookies sind für die Grundfunktionen des Shops notwendig.
"Alle Cookies ablehnen" Cookie
"Alle Cookies annehmen" Cookie
Ausgewählter Shop
CSRF-Token
Cookie-Einstellungen
FACT-Finder Tracking
Individuelle Preise
Kundenspezifisches Caching
Session
Währungswechsel
Komfortfunktionen
Diese Cookies werden genutzt um das Einkaufserlebnis noch ansprechender zu gestalten, beispielsweise für die Wiedererkennung des Besuchers.
Facebook-Seite in der rechten Blog - Sidebar anzeigen
Merkzettel
Statistik & Tracking
Endgeräteerkennung
Kauf- und Surfverhalten mit Google Tag Manager
Partnerprogramm
Zu "K08529" wurden 41 Artikel gefunden!
Filter schließen
Filtern nach:
Für die Filterung wurden keine Ergebnisse gefunden!
Artikelnummer: ELK-ELK4437.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human RARg. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human RARg. Next,...
Schlagworte: | RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: IB-IB02001
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoic acid receptor gamma (NR1B3), a ligand-dependent transcription factor commonly referred to as RARG or RARgamma. INDIGO's reporter cells include the luciferase...
Schlagworte: | RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3 |
Anwendung: | Functional activity screening |
Spezies-Reaktivität: | human |
ab 1.448,00 €
Artikelnummer: Cay71610-5
CD437 is the prototypical adamantyl arotinoid of the retinoid-related molecule family that acts as a selective agonist of retinoic acid receptor (RAR)gamma (Kds = 6.5 µM, 2.5 µM, and 77 nM for RARalpha, beta, and gamma, respectively). CD437 is cytotoxic to the acute myeloid leukemia cell line NB4 (EC50 = 0.17 µM),...
Schlagworte: | AHPN, 6-(4-hydroxy-3-tricyclo[3.3.1.13,7]dec-1-ylphenyl)-2-naphthalenecarboxylic acid |
Anwendung: | RAR gamma agonist |
CAS | 125316-60-1 |
MW: | 398.5 D |
ab 115,00 €
Artikelnummer: BPS-60604
The RAR gamma Reporter (Luc)-HEK293 cell line is designed for monitoring the activity of RARgamma. The RAR gamma Reporter (Luc)-HEK293 cell line contains a firefly luciferase gene under the control of retinoic acid response elements stably integrated into HEK293 cells along with full length human RARgamma (accession...
Schlagworte: | RARG, NR1B3, RAR-gamma, Retinoic acid receptor gamma, Nuclear receptor subfamily 1 group B member 3, |
Anwendung: | RARgamma reporter assays |
2.719,00 €
Artikelnummer: Cay17688-50
Fenretinide is a synthetic derivative of retinoic acid (Cay-11017) and an inhibitor of dihydroceramide desaturase (IC50 = 2.32 µM). It promotes the generation of reactive oxygen species (ROS), the degradation of anti-apoptotic MCL-1, and the cleavage of pro-apoptotic PKCdelta. At 5-20 µM, fenretinide selectively...
Schlagworte: | 4-HPR, 4-Hydroxy(phenyl)retinamide, MK-4016, Retinoic Acid p-hydroxyphenylamide, Ro 22-4667, N-(4-hydroxyphenyl)-retinamide |
Anwendung: | Retinoic acid receptor gamma activator |
CAS | 65646-68-6 |
MW: | 391.6 D |
ab 125,00 €
Artikelnummer: Cay16031-10
CD2665 is a selective retinoic acid receptor (RAR)beta and RARgamma antagonist (Kds = 110, 306, and > 2,250 nM for RARgamma, RARbeta, and RARalpha, respectively, with no binding at RXRalpha). At 10-7 M, it has been used to abrogate retinoic acid (Cay-11017)-induced antiproliferative and antidifferentiative effects...
Schlagworte: | 4-[6-[(2-methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl]-benzoic acid |
Anwendung: | RAR beta / gamma antagonist |
CAS | 170355-78-9 |
MW: | 486.6 D |
ab 50,00 €
Artikelnummer: Cay19878-25
Etretinate is a second-generation retinoid previously used systemically to manage psoriasis but withdrawn due to teratogenicity. Etretinate alters cAMP signaling, which may be defective in psoriasis.Formal Name: (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, ethyl ester....
Schlagworte: | Ro 10-9359, Tegison, (2E,4E,6E,8E)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethyl-2,4,6,8-nonatetraenoic acid, ethyl ester |
Anwendung: | Retinoid, Antipsoriatic, RAR agonist |
CAS | 54350-48-0 |
MW: | 354.5 D |
ab 43,00 €
Artikelnummer: Cay19062-1
CD1530 is a selective retinoic acid receptor (RARgamma) agonist (Kds = 150, 1,500, and 2,750 nM for RARgamma, RARbeta, and RARalpha receptors, respectively). It demonstrates transcriptional activity at RARgamma with an AC50 value of 1.8 nM. It has been used in combination with bexarotene (Cay-11571), a retinoid X...
Schlagworte: | 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-benzoic acid |
Anwendung: | RAR gamma agonist |
CAS | 107430-66-0 |
MW: | 398.5 D |
ab 52,00 €
Artikelnummer: Cay21800-1
MM-11253 is a synthetic, conformationally restricted retinoid that acts as a selective antagonist of retinoic acid receptor gamma (RARgamma). It dose-dependently blocks the ability of RARgamma-selective agonists, but not retinoic acid (all-trans retinoic acid, Cay-11017), to inhibit the growth of oral squamous cell...
Schlagworte: | 6-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthalenecarboxylic acid |
Anwendung: | RARgamma antagonist |
CAS | 345952-44-5 |
MW: | 462.7 D |
ab 52,00 €
Artikelnummer: LKT-A0933.25
A metabolite of etretinate. It is primarily used to treat skin disorders. It also appears to suppress the development of squamous cell carcinoma and chemically-induced epithelial tumors.
Schlagworte: | Soriatane, 9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid |
CAS | 55079-83-9 |
MW: | 326.43 D |
ab 94,00 €
Artikelnummer: Cay25833-1
LY2955303 is a potent antagonist of retinoic acid receptor gamma (RARgamma, Ki = 1.1 nM). It is selective for RARgamma over RARalpha and RARbeta (Kis = >1,700 and >2,980 nM, respectively). LY2955303 reduces differential weight bearing between the contralateral and ipsilateral limbs in a rat model of...
Schlagworte: | 4-[5-[3,5-bis(1,1-dimethylethyl)phenyl]-1-[4-[(4-methyl-1-piperazinyl)carbonyl]phenyl]-1H-pyrazol-3-yl]-benzoic acid |
Anwendung: | RARgamma antagonist |
CAS | 1433497-19-8 |
MW: | 578.7 D |
ab 43,00 €
Artikelnummer: Cay28460-5
Palovarotene an orally bioavailable retinoic acid receptor gamma (RARgamma) agonist. It increases retinoic acid response element (RARE) activity and decreases NF-kappaB activity induced by IL-1beta in primary mouse stromal cells in reporter assays when used at a concentration of 60 nM. Palovarotene (10 nM) inhibits...
Schlagworte: | Ro 3300074, 4-[(1E)-2-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]-benzoic acid |
Anwendung: | Retinoic acid receptor gamma agonist |
CAS | 410528-02-8 |
MW: | 414.5 D |
ab 109,00 €