Zu "K08526" wurden 49 Artikel gefunden!
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Bexarotene
Artikelnummer: Cay11571-50
Bexarotene is an agonist of retinoid X receptors (RXRs, EC50s = 28, 25, and 20 nM for RXRalpha, RXRbeta, and RXRgamma, respectively, in reporter assays). It is selective for RXRs over retinoic acid receptors (RARs, EC50s = >10 µM for RARalpha, RARbeta, and RARgamma). Bexarotene (10 µM) induces apoptosis in MJ, HuT...
| Schlagworte: | LG 100069, LGD 1069, Ro 26-4455, SR 11247, 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic... |
| Anwendung: | Retinoid X receptor ligand |
| CAS | 153559-49-0 |
| MW: | 348.5 D |
ab 38,00 €
RXRgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00821
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
ab 1.588,00 €
9-cis-Retinoic acid
Artikelnummer: LKT-R1777.1
A vitamin A analog that inhibits cell proliferation and induces cell differentiation.
| Schlagworte: | Alitretinoin |
| Anwendung: | Chemopreventive agent, retinoid receptor agonist |
| CAS | 5300-03-8 |
| MW: | 300,44 D |
ab 108,00 €
HX 531
Artikelnummer: Cay20762-5
HX 531 is an antagonist of the retinoid X receptor (RXR) with an IC50 value of 18 nM that inhibits 9-cis retinoic acid (Cay-14587)-induced transactivation of RXR. It has been shown to reduce triglyceride content in white adipose tissue, skeletal muscle, and the liver of mice on a high fat diet.Formal Name:...
| Schlagworte: | 4-(7,8,9,10-tetrahydro-5,7,7,10,10-pentamethyl-2-nitro-5H-benzo[b]naphtho[2,3-e][1,4]diazepin-12-yl)-benzoic acid |
| Anwendung: | RXR antagonist |
| CAS | 188844-34-0 |
| MW: | 483.6 D |
ab 49,00 €
Bexarotene
Artikelnummer: LKT-B1992.25
Bexarotene is an oral antineoplastic agent used for cutaneous T cell lymphoma. Researchers have discovered that bexarotene reduced amyloid plaque and that could be used to treat Alzheimer's symptoms.
| Schlagworte: | Targretin, Targretyn, LGD-1069 |
| CAS | 153559-49-0 |
| MW: | 348.48 D |
ab 100,00 €
Anti-Retinoid X Receptor gamma, Internal
Artikelnummer: ARG63664.100
Protein function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response...
| Schlagworte: | Anti-RXRG, Anti-NR2B3, Anti-Retinoid X receptor gamma, Anti-Retinoic acid receptor RXR-gamma, Anti-Nuclear receptor... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Mouse Rxrg / Retinoic acid receptor RXR-gamma ELISA Kit
Artikelnummer: G-MOFI00406.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
RXRgamma (human) Reporter Assay Kit
Artikelnummer: IB-IB00822
This nuclear receptor assay system utilizes proprietary non-human cells engineered to provide constitutive, high-level expression of the human retinoid X receptor gamma (NR2B3), a ligand-dependent transcription factor commonly referred to as RXRG or RXRgamma. INDIGO's reporter cells include the luciferase reporter...
| Schlagworte: | RXRG, NR2B3, Retinoid X receptor gamma, Retinoic acid receptor RXR-gamma, Nuclear receptor subfamily 2 group B member 3 |
| Anwendung: | Functional activity screening |
| Spezies-Reaktivität: | human |
4.175,00 €
Anti-Retinoid X Receptor gamma, clone 1373
Artikelnummer: 209-301-E28
Anti-Retinoic Acid Receptor gamma antibody detects Retinoic Acid Receptor gamma. Retinoic Acid Receptor gamma antibody was Protein G purified. This antibody is directed against human retinoic acid receptor gamma protein. Reactivity is predicted with RAR gamma from bovine, canine and mouse based on 100% sequence...
| Schlagworte: | Anti-RXRG, Anti-NR2B3, Anti-Retinoid X receptor gamma, Anti-Retinoic acid receptor RXR-gamma, Anti-Nuclear receptor... |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
881,00 €
Anti-RXRG
Artikelnummer: NSJ-R35739-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Retinoid X receptor gamma, RXR gamma Protein function: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands,...
| Schlagworte: | Anti-RXRG, Anti-NR2B3, Anti-Retinoid X receptor gamma, Anti-Retinoic acid receptor RXR-gamma, Anti-Nuclear receptor... |
| Anwendung: | WB, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Bexarotene-d4
Artikelnummer: Cay22610-1
Bexarotene-d4 is intended for use as an internal standard for the quantification of bexarotene (Cay-11571) by GC- or LC-MS. Bexarotene is a high-affinity ligand for retinoid X receptors (RXRs) (EC50s = 28, 25, and 20 nM for RXRalpha, beta, and gamma, respectively). It inhibits cell cycle progression, induces...
| Schlagworte: | 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-benzoic acid-d4 |
| Anwendung: | GC-MS, LC-MS, internal standard, retinoid X receptor ligand |
| CAS | 2182068-00-2 |
| MW: | 352.5 D |
450,00 €
UVI3003
Artikelnummer: Cay16026-50
UVI3003 is a full antagonist of RXR that demonstrates potent, nanomolar binding affinity. At 1 µM, UVI3003 does not affect the corepressor interaction capacity of the RARalpha subunit in the RAR-RXR heterodimer configuration. This compound can be used to isolate the contribution of RXR to the function of RXR...
| Schlagworte: | 3-[4-hydroxy-3-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(pentyloxy)-2-naphthalenyl]phenyl]-2-propenoic acid |
| Anwendung: | RXR antagonist |
| CAS | 847239-17-2 |
| MW: | 436.6 D |
ab 145,00 €