Zu "K08428" wurden 18 Artikel gefunden!
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NEU
NCRW0005-F05
Artikelnummer: Cay43215-10
NCRW0005-F05 is an antagonist of G protein-coupled receptor 139 (GPR139, IC50 = 0. µM).. Solulibility: DMSO: Soluble: = 10 mg/ml: Ethanol: Sparingly soluble: 1-10 mg/ml.
| Schlagworte: | 3,3-difluoro-4-(4-methoxyphenyl)-1-phenyl-2-azetidinone |
| Anwendung: | GPR139 antagonist |
| CAS | 342779-66-2 |
| MW: | 289.28 D |
ab 117,00 €
TAK-041
Artikelnummer: TGM-T9317-100mg
Description: TAK-041 (NBI-1065846) is a potent and selective GPR139 agonist. Target: GPR. Smiles: C[C@H](NC(=O)Cn1nnc2ccccc2c1=O)c1ccc(OC(F)(F)F)cc1. References: Reichard HA, et al. Discovery of TAK-041: a Potent and Selective GPR139 Agonist Explored for the Treatment of Negative Symptoms Associated with...
| Schlagworte: | NBI-1065846 |
| Anwendung: | GPR139 agonist |
| CAS | 1929519-13-0 |
| MW: | 392.33 D |
ab 31,00 €
JNJ-63533054
Artikelnummer: TGM-T3119-100mg
Description: JNJ-63533054 is a potent and selective agonist of hGPR139 with an EC50 = 16 nM. Target: GPR. Smiles: C[C@H](NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1. References: Dvorak CA, et al. ACS Med Chem Lett. 2015 Jul 20,6(9):1015-8.
| Schlagworte: | JNJ 63533054 |
| Anwendung: | GPR139 agonist |
| CAS | 1802326-66-4 |
| MW: | 316.78 D |
ab 31,00 €
Anti-GPR139
Artikelnummer: CSB-PA007021.50
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Anwendung: | ELISA, WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
126,00 €
TC-O 9311
Artikelnummer: Cay14030-1
TC-O 9311 is an agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 39 nM in a calcium mobilization assay). It is selective for GPR139 over a panel of 90 additional targets. TC-O 9311 (1 µM) inhibits cell death induced by 1-methyl-4-phenylpyridinium (MPP+), but not 6-hydroxydopamine (6-OHDA, Cay-25330),...
| Schlagworte: | 3,5-dimethoxy-benzoic acid, 2-[(1-naphthalenylamino)carbonyl]hydrazide |
| Anwendung: | Potent GPR139 agonist |
| CAS | 444932-31-4 |
| MW: | 365.4 D |
ab 44,00 €
JNJ-63533054
Artikelnummer: Cay23450-1
JNJ-63533054 is a potent agonist of the orphan G protein-coupled receptor GPR139 (EC50 = 16 nM in HEK293 cells expressing human GPR139). It is selective for GPR139 over 50 known G protein-coupled receptors, ion channels, and transporters as determined by an external selectivity panel. Tritium-labeled JNJ-63533054...
| Schlagworte: | 3-chloro-N-[2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]-benzamide |
| Anwendung: | GPR139 agonist |
| CAS | 1802326-66-4 |
| MW: | 316.8 D |
ab 44,00 €
Anti-GPR139
Artikelnummer: E-AB-18037.120
This gene encodes a member of the rhodopsin family of G-protein-coupled receptors. The encoded protein is almost exclusively expressed in the central nervous system. L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein. Alternative splicing results in multiple transcript...
| Schlagworte: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 89,00 €
Anti-GPR139
Artikelnummer: ATA-HPA046596.100
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity to mouse: 98% and to rat: 98%
| Schlagworte: | Anti-GPRG1, Anti-GPR139, Anti-G-protein-coupled receptor PGR3, Anti-G(q)-coupled orphan receptor GPRg1, Anti-Probable... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 239,00 €
TAK-041
Artikelnummer: Cay36108-1
TAK-041 is an agonist of G protein-coupled receptor 139 (GPR139). It induces calcium mobilization in cells expressing human GPR139 (EC50 = 22 nM). In vivo, TAK-041 (0.3 and 3 mg/kg) increases social interaction in mice.Formal Name:...
| Schlagworte: | NBI 1065864, 4-oxo-N-[(1S)-1-[4-(trifluoromethoxy)phenyl]ethyl]-1,2,3-benzotriazine-3(4H)-acetamide |
| Anwendung: | GPR139 agonist |
| CAS | 1929519-13-0 |
| MW: | 392.3 D |
ab 44,00 €
Nanodisc Human GP139-Strep Protein
Artikelnummer: G-HDFP990.10
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium]
| Schlagworte: | GPRG1, GPR139, G-protein-coupled receptor PGR3, G(q)-coupled orphan receptor GPRg1, Probable G-protein coupled receptor 139 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.336,00 €
Nanodisc Human GP139 Protein
Artikelnummer: G-HDFP254.10
Protein function: Orphan receptor. Seems to act through a G(q/11)-mediated pathway. [The UniProt Consortium]
| Schlagworte: | GPRG1, GPR139, G-protein-coupled receptor PGR3, G(q)-coupled orphan receptor GPRg1, Probable G-protein coupled receptor 139 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
1.486,00 €
GP139 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100263.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | GPRG1, GPR139, G-protein-coupled receptor PGR3, G(q)-coupled orphan receptor GPRg1, Probable G-protein coupled receptor... |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 40.7 kD |
ab 1.291,00 €