Zu "K08413" wurden 14 Artikel gefunden!
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ML-193
Artikelnummer: Cay15184-1
ML-193 is a potent antagonist of GPR55 (IC50 = 221 nM). It displays selectivity for GPR55 over CB1, CB2, and GPR35. ML-193 inhibits GPR55-dependent ERK phosphorylation (IC50 = 65 nM) and blocks translocation of PKCbetaII. ML-193 blocks increases in intracellular calcium levels induced by lysophosphatidylinositol...
| Schlagworte: | CID-1261822, N-[4-[[(3,4-dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide |
| Anwendung: | Potent GPR55 antagonist |
| CAS | 713121-80-3 |
| MW: | 527.6 D |
ab 43,00 €
ML-184
Artikelnummer: Cay17641-5
GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 µM lysophosphatidylinositol (LPI). ML-184 is a potent synthetic agonist of GPR55 (EC50 = 0.26 µM). It does not act at the related kynurenic...
| Schlagworte: | CID-2440433, 3-[[4-(2,3-dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)-benzenesulfonamide |
| Anwendung: | GPR55 agonist |
| CAS | 794572-10-4 |
| MW: | 470.6 D |
ab 35,00 €
ML-192
Artikelnummer: Cay15183-5
ML-192 is an antagonist of GPR55 (IC50 = 702 nM). It is selective for GPR55 over the cannabinoid (CB) receptors CB1 and CB2, as well as GPR35 (IC50s = >32 µM).Formal Name: 2-furanyl[4-(5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-methanone. CAS Number: 460331-61-7. Synonyms:...
| Schlagworte: | CID-1434953, 2-furanyl[4-(5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-methanone |
| Anwendung: | GPR55 antagonist |
| CAS | 460331-61-7 |
| MW: | 382.5 D |
ab 97,00 €
CID-16020046
Artikelnummer: Cay15247-1
CID-16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 µM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 µM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2...
| Schlagworte: | 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid |
| Anwendung: | GPR55 inverse agonist |
| CAS | 834903-43-4 |
| MW: | 425.4 D |
ab 48,00 €
Anti-GPR55
Artikelnummer: E-AB-17848.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 71,00 €
Anti-GPR55
Artikelnummer: E-AB-19749.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 71,00 €
Anti-GPR55
Artikelnummer: E-AB-65977.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
ab 198,00 €
Anti-GPR55
Artikelnummer: G-CAB12890.100
WB 1:500 - 1:2000, IF 1:50 - 1:200. Protein function: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L- alpha-lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via the heterotrimeric G protein GNA13 and RHOA. Putative cannabinoid...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody (CAB12890) |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
ab 352,00 €
Anti-GPR55
Artikelnummer: ELK-ES11475.100
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. [provided by RefSeq, Aug 2013], Protein function:...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 rabbit pAb |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse, |
ab 169,00 €
Anti-GPR55
Artikelnummer: Cay10224-1
GPR55 is an orphan G protein-coupled receptor. GPR55 is expressed in the brain, large dorsal root ganglion neurons, and many peripheral tissues. Endogenous agonists for GPR55 include lysophosphatidylinositol (EC50 = 1.2 µM in a beta-arrestin-GFP biosensor assay) and the endocannabinoids anandamide (arachidonoyl...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, Anti-G-protein coupled receptor 55 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, murine |
422,00 €
GPR55, Human G protein-coupled receptor 55, Real Time PCR...
Artikelnummer: VHPS-3806
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | GPR55, G-protein coupled receptor 55 |
| Anwendung: | RNA quantification |
43,00 €
Gpr55, Mouse G protein-coupled receptor 55, Real Time PCR...
Artikelnummer: VMPS-2584
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
| Schlagworte: | Gpr55, G protein-coupled receptor 55 |
| Anwendung: | RNA quantification |
43,00 €