Zu "K08413" wurden 23 Artikel gefunden!
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ML192
Artikelnummer: TGM-T33452-100mg
Description: ML192 (CID1434953) is a selective GPR55 ligand antagonist. ML192 is an inhibitor that inhibits beta-arrestin transport, ERK1/2 phosphorylation, and PKCbetaII translocation. Target: GPR, Cannabinoid Receptor, Arrestin. Smiles: Cc1nc(N2CCN(CC2)C(=O)c2ccco2)c2c3CCCCc3sc2n1. References: Kotsikorou E, et...
| Schlagworte: | CID 1434953, CID1434953, ML-192, CID-1434953, ML 192 |
| Anwendung: | GPR55 antagonist |
| CAS | 460331-61-7 |
| MW: | 382.48 D |
ab 31,00 €
CID 16020046
Artikelnummer: TGM-T4478-100mg
Description: CID 16020046 (C390-0219) is a selective GPR55 antagonist, inhibiting GPR55 constitutive activity with IC50 of 0.15 µM in yeast. Target: Cannabinoid Receptor. Smiles: Cc1ccc(cc1)-c1n[nH]c2C(=O)N(C(c12)c1cccc(O)c1)c1ccc(cc1)C(O)=O. References: Kargl J, et al. A selective antagonist reveals a potential...
| Schlagworte: | C390-0219 |
| Anwendung: | GPR55 inverse agonist |
| CAS | 834903-43-4 |
| MW: | 425.44 D |
ab 34,00 €
Human GPR55(1-21) Protein, hFc Tag
Artikelnummer: DIM-PME100757.10
Recombinant human GPR55(1-21) protein with C-terminal human Fc tag. GPR55(Met1-Thr21) hFc(Glu99-Ala330), Protein function: May be involved in hyperalgesia associated with inflammatory and neuropathic pain. Receptor for L-alpha- lysophosphatidylinositol (LPI). LPI induces Ca(2+) release from intracellular stores via...
| Schlagworte: | G-protein coupled receptor 55 |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| CAS | 12 |
| MW: | 28.5 kD |
ab 103,00 €
GPR55 (human) full length protein-synthetic nanodisc
Artikelnummer: DIM-FLP100054.10
Discover a breakthrough in membrane protein research and drug development with DIMA Biotech's Synthetic Nanodiscs. Traditional methods struggle with challenges in obtaining water-soluble and bioactive forms of multi-transmembrane proteins. Our innovative polymer-based Nanodisc platform offers a game-changing...
| Schlagworte: | GPR55, G-protein coupled receptor 55, LPIR1, Human GPR55 full length protein-synthetic nanodisc |
| Anwendung: | Full length transmembrane protein, FA, ELISA, screening, immunization, cell-based assays, crystallization |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 36.6 kD |
ab 1.291,00 €
ML-193
Artikelnummer: Cay15184-1
ML-193 is a potent antagonist of GPR55 (IC50 = 221 nM). It displays selectivity for GPR55 over CB1, CB2, and GPR35. ML-193 inhibits GPR55-dependent ERK phosphorylation (IC50 = 65 nM) and blocks translocation of PKCbetaII. ML-193 blocks increases in intracellular calcium levels induced by lysophosphatidylinositol...
| Schlagworte: | CID-1261822, N-[4-[[(3,4-dimethyl-5-isoxazolyl)amino]sulfonyl]phenyl]-6,8-dimethyl-2-(2-pyridinyl)-4-quinolinecarboxamide |
| Anwendung: | Potent GPR55 antagonist |
| CAS | 713121-80-3 |
| MW: | 527.6 D |
ab 44,00 €
ML-184
Artikelnummer: Cay17641-5
GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 µM lysophosphatidylinositol (LPI). ML-184 is a potent synthetic agonist of GPR55 (EC50 = 0.26 µM). It does not act at the related kynurenic...
| Schlagworte: | CID-2440433, 3-[[4-(2,3-dimethylphenyl)-1-piperazinyl]carbonyl]-N,N-dimethyl-4-(1-pyrrolidinyl)-benzenesulfonamide |
| Anwendung: | GPR55 agonist |
| CAS | 794572-10-4 |
| MW: | 470.6 D |
ab 36,00 €
CID-16020046
Artikelnummer: Cay15247-1
CID-16020046 is a GPR55 inverse agonist that antagonizes GPR55 constitutive activity with an IC50 value of 15 µM. It inhibits GPR55-mediated ERK1/2 phosphorylation, LPI-induced Ca2+ signaling (IC50 = 0.21 µM in HEK-GPR55 cells), and GPR55-mediated transcription factor activation. It does not affect ERK1/2...
| Schlagworte: | 4-[4,6-dihydro-4-(3-hydroxyphenyl)-3-(4-methylphenyl)-6-oxopyrrolo[3,4-c]pyrazol-5(1H)-yl]-benzoic acid |
| Anwendung: | GPR55 inverse agonist |
| CAS | 834903-43-4 |
| MW: | 425.4 D |
ab 49,00 €
Anti-GPR55
Artikelnummer: Cay10224-1
GPR55 is an orphan G protein-coupled receptor. GPR55 is expressed in the brain, large dorsal root ganglion neurons, and many peripheral tissues. Endogenous agonists for GPR55 include lysophosphatidylinositol (EC50 = 1.2 µM in a beta-arrestin-GFP biosensor assay) and the endocannabinoids anandamide (arachidonoyl...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, Anti-G-protein coupled receptor 55 |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, bovine, murine |
431,00 €
ML-192
Artikelnummer: Cay15183-5
ML-192 is an antagonist of GPR55 (IC50 = 702 nM). It is selective for GPR55 over the cannabinoid (CB) receptors CB1 and CB2, as well as GPR35 (IC50s = >32 µM).Formal Name: 2-furanyl[4-(5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-methanone. CAS Number: 460331-61-7. Synonyms:...
| Schlagworte: | CID-1434953, 2-furanyl[4-(5,6,7,8-tetrahydro-2-methyl[1]benzothieno[2,3-d]pyrimidin-4-yl)-1-piperazinyl]-methanone |
| Anwendung: | GPR55 antagonist |
| CAS | 460331-61-7 |
| MW: | 382.5 D |
ab 99,00 €
Anti-GPR55
Artikelnummer: E-AB-17848.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-GPR55
Artikelnummer: E-AB-19749.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €
Anti-GPR55
Artikelnummer: E-AB-65977.120
This gene belongs to the G-protein-coupled receptor superfamily. The encoded integral membrane protein is a likely cannabinoid receptor. It may be involved in several physiological and pathological processes by activating a variety of signal transduction pathways. Protein function: May be involved in hyperalgesia...
| Schlagworte: | Anti-GPR55, Anti-G-protein coupled receptor 55, GPR55 Polyclonal Antibody |
| Anwendung: | WB, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | mouse, rat |
ab 243,00 €