Zu "K08292" wurden 47 Artikel gefunden!
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NH125
Artikelnummer: Cay10011250-1
NH125 is an imidazole that has potent antibacterial properties in drug-resistant bacteria. In bacteria, NH125 inhibits several histidine kinases, inhibiting YycG with an IC50 of 6.6 µM. NH125 also decreases the viability of several cancer cell lines with IC50 values ranging from 0.7-4.7 µM. In mammalian cells, NH125...
| Schlagworte: | 1-hexadecyl-2-methyl-3-(phenylmethyl)-1H-imidazolium-iodide |
| Anwendung: | eEF-2K inhibitor |
| CAS | 278603-08-0 |
| MW: | 524.6 D |
ab 60,00 €
A-484954
Artikelnummer: Cay28279-1
A-484954 is an ATP-competitive inhibitor of eukaryotic elongation factor-2 kinase (eEF-2K, IC50 = 420 nM). It reduces eEF-2K autophosphorylation in PC3, HeLa, H460, H1299, and MDA-MB-231 cancer cells when used at a concentration of 75 µM.Formal Name:...
| Schlagworte: | 7-amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxo-pyrido[2,3-d]pyrimidine-6-carboxamide |
| Anwendung: | ATP-competitive eukaryotic elongation factor-2 kinase (eEF-2K) inhibitor |
| CAS | 142557-61-7 |
| MW: | 289.3 D |
ab 49,00 €
NH125
Artikelnummer: TGM-T6605-5mg
Description: NH125 is a selective eEF-2 kinase inhibitor with IC50 of 60 nM, >125-fold selectivity over PKC, PKA, and CaMKII, and also a potent histidine kinase inhibitor. Target: Autophagy, CaMK, Antibacterial, Antifungal, Virus Protease, PKC, PKA. Smiles: [I-].CCCCCCCCCC CCCCCCn1cc[n+](Cc2ccccc2)c1C....
| Anwendung: | eEF-2K inhibitor |
| CAS | 278603-08-0 |
| MW: | 524.56 D |
ab 33,00 €
Anti-eEF2 Kinase
Artikelnummer: A301-686A
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-eEF2 Kinase
Artikelnummer: A301-687A
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
Mouse Eef2k / Eukaryotic elongation factor 2 kinase ELISA...
Artikelnummer: G-MOFI00355.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-eEF2 Kinase (IHC)
Artikelnummer: IHC-00331
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | IHC, IHC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 165,00 €
TX-1918
Artikelnummer: Cay20840-1
TX-1918 is a cell-permeable tyrphostin derivative that inhibits eukaryotic elongation factor-2 kinase (eEF-2K, IC50 = 440 nM). It inhibits Src, PKA, PKC, and EGFR kinases at much higher concentrations (IC50s = 4.4, 44, 44, and 440 µM, respectively). TX-1918 disrupts the proliferation of HepG2 and HCT116 tumor cells...
| Schlagworte: | 2-[(4-hydroxy-3,5-dimethylphenyl)methylene]-4-cyclopentene-1,3-dione |
| Anwendung: | Cell-permeable eEF-2K inhibitor |
| CAS | 503473-32-3 |
| MW: | 228.2 D |
ab 49,00 €
Anti-Phospho-eEF2K (Ser366)
Artikelnummer: E-AB-21142.120
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2...
| Schlagworte: | Anti-phospho-EEF2K, Anti-phospho-eEF-2K, Anti-phospho-eEF-2 kinase, Anti-phospho-Eukaryotic elongation factor 2 kinase,... |
| Anwendung: | WB, IHC (paraffin), ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 89,00 €
Anti-eEF2k
Artikelnummer: ARG59005.100
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
616,00 €
Anti-eEF2k
Artikelnummer: ARG59006.100
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-EEF2K
Artikelnummer: ATA-HPA056061.100
Protein function: Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In...
| Schlagworte: | Anti-EEF2K, Anti-eEF-2K, Anti-eEF-2 kinase, Anti-Eukaryotic elongation factor 2 kinase, Anti-Calcium/calmodulin-dependent... |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 369,00 €