Zu "K08269" wurden 43 Artikel gefunden!
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ATG1 Protein, Candida glabrata, Recombinant (His)
Artikelnummer: TGM-TMPH-00340-100ug
Description: ATG1 Protein, Candida glabrata, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.4 kDa and the accession number is Q6FL58.
| Schlagworte: | ATG1, Autophagy-related protein 1, Serine/threonine-protein kinase ATG1 |
| MW: | 38.4 kD |
ab 359,00 €
MRT68921
Artikelnummer: TGM-T6899-100mg
Description: MRT68921 is a potent and dual autophagy kinase ULK1/2 inhibitor with IC50 of 2.9 nM and 1.1 nM, respectively. Target: Autophagy. Smiles: N(CCCNC(=O)C1CCC1)C=2C(=CN=C(NC=3C=C4C(=CC3)CN(C)CC4)N2)C5CC5. References: Petherick KJ, et al. J Biol Chem. 2015, 290(18), 11376-11383.
| Schlagworte: | MRT68921 HCl |
| Anwendung: | Cell-permeable, potent, specific ULK1 & ULK2 inhibitor |
| CAS | 1190379-70-4 |
| MW: | 434.58 D |
ab 37,00 €
sbp-7455
Artikelnummer: TGM-T8850-100mg
Description: SBP-7455 potently inhibited ULK1/2 enzymatic activity in vitro and in cells, reduced the viability of TNBC cells and had oral bioavailability in mice. Target: Autophagy. Smiles: COc1ccc(Nc2ncc(c(NC3CC3)n2)C(F)(F)F)cc1OC. References: Ren H, Bakas NA, Vamos M, et al. Design, Synthesis, and...
| Anwendung: | ULK1 / ULK2 dual inhibitor |
| CAS | 1884222-74-5 |
| MW: | 354.33 D |
ab 60,00 €
Anti-ULK2
Artikelnummer: CSB-PA461940.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-ULK2, Anti-KIAA0623, EC=2.7.11.1, Anti-Unc-51-like kinase 2, Anti-Serine/threonine-protein kinase ULK2, ATG1B... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Anti-ULK2
Artikelnummer: CSB-PA471712.100
Host Species: Rabbit. Isotype: IgG. Buffer: PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific...
| Schlagworte: | Anti-ULK2, Anti-KIAA0623, EC=2.7.11.1, Anti-Unc-51-like kinase 2, Anti-Serine/threonine-protein kinase ULK2, ATG1B... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 126,00 €
Serine/threonine-protein kinase ATG1 (ATG1), partial,...
Artikelnummer: CSB-EP738902CZI.1
Organism: Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata). Source: E.coli. Expression Region: 11-312aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-tagged. Target Protein Sequence: YVVEKEIGKG SFATVYRGHV TTDPKSHIAV KAVARSKLKN KKLLENLEIE IAILKKIKHP...
| Schlagworte: | Autophagy-related protein 1, Serine/threonine-protein kinase ATG1, Recombinant Candida glabrata Serine/threonine-protein... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Candida glabrata |
| MW: | 38.4 kD |
ab 364,00 €
Serine/threonine-protein kinase ATG1 (ATG1), partial,...
Artikelnummer: CSB-EP738902CZIa2.1
Organism: Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata). Source: E.coli. Expression Region: 11-312aa. Protein Length: Partial. Tag Info: N-terminal 6xHis-SUMO-tagged. Target Protein Sequence: YVVEKEIGKG SFATVYRGHV TTDPKSHIAV KAVARSKLKN KKLLENLEIE...
| Schlagworte: | Autophagy-related protein 1, Serine/threonine-protein kinase ATG1, Recombinant Candida glabrata Serine/threonine-protein... |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | Candida glabrata |
| MW: | 50.4 kD |
ab 364,00 €
SBI-0206965
Artikelnummer: Cay18477-5
ULK1 is a serine/threonine kinase that acts upstream of phosphatidylinositol 3-kinase (PI3K) to regulate the formation of autophagophores, the precursors of autophagosomes, in response to nutrient deprivation. It is activated by phosphorylation by AMPK and, in turn, phosphorylates and inhibits AMPK. SBI-0206965 is...
| Schlagworte: | 2-[[5-bromo-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]oxy]-N-methyl-benzamide |
| Anwendung: | ULK1 inhibitor |
| CAS | 1884220-36-3 |
| MW: | 489.3 D |
ab 100,00 €
MRT68921
Artikelnummer: Cay19905-1
MRT68921 is an inhibitor of ULK1 and ULK2 (IC50s = 2.9 and 1.1 nM, respectively). Through its effects on ULK1, MRT68921 blocks autophagy in cells, driving the accumulation of stalled early autophagosomal structures.Formal Name:...
| Schlagworte: | N-[3-[[5-cyclopropyl-2-[(1,2,3,4-tetrahydro-2-methyl-6-isoquinolinyl)amino]-4-pyrimidinyl]amino]propyl]-cyclobutanecarboxa... |
| Anwendung: | Cell-permeable, potent, specific ULK1 & ULK2 inhibitor |
| CAS | 1190379-70-4 |
| MW: | 434.6 D |
ab 44,00 €
ULK2, GST-tag
Artikelnummer: BPS-40294
Recombinant human ULK2 (a.a. 1-478), with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.
| Schlagworte: | ULK2, KIAA0623, EC=2.7.11.1, Unc-51-like kinase 2, Serine/threonine-protein kinase ULK2, |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 98 kD |
1.017,00 €
Anti-UNG1
Artikelnummer: 600-401-FV1
Anti-UNG1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with UNG1 from other sources has not been determined. Protein function: Serine/threonine-protein kinase involved in autophagy in response to starvation. Acts upstream of phosphatidylinositol 3-...
| Schlagworte: | Anti-ULK2, Anti-KIAA0623, EC=2.7.11.1, Anti-Unc-51-like kinase 2, Anti-Serine/threonine-protein kinase ULK2 |
| Anwendung: | ELISA, IHC, IFM, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
834,00 €
SBP-7455
Artikelnummer: Cay32988-1
SBP-7455 is a dual inhibitor of unc-51-like autophagy activating kinase 1 (ULK1) and ULK2 (IC50s = 13 and 476 nM, respectively, for the recombinant human enzymes in cell-free assays). It inhibits increases in autophagic flux and induces apoptosis in serum-deprived MDA-MB-468 breast cancer cells when used at a...
| Schlagworte: | N4-cyclopropyl-N2-(3,4-dimethoxyphenyl)-5-(trifluoromethyl)-2,4-pyrimidinediamine |
| Anwendung: | ULK1 / ULK2 dual inhibitor |
| CAS | 1884222-74-5 |
| MW: | 354.3 D |
ab 48,00 €