Zu "K08268" wurden 137 Artikel gefunden!
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Anti-HIF-1alpha (C-Term)
Artikelnummer: Cay10006421-1
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a transcription factor that accumulates under low-oxygen conditions. Following hypoxic stimulus and cytoplasmic accumulation, HIF-1alpha migrates to the nucleus where with other transcription factors, it drives the production of stress-adaptive proteins. This response...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-bHLHe78, Anti-ARNT-interacting protein, Anti-ARNT-interacting protein, Anti-PAS... |
| Anwendung: | IHC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
422,00 €
Anti-HIF1A / HIF-1 alpha
Artikelnummer: NSJ-RQ5614
0.5mg/ml if reconstituted with 0.2ml sterile DI water. HIF-1a (Hypoxia-inducible factor 1 alpha or HIF1A) is a transcription factor that mediates cellular and systemic homeostatic responses to reduced O2 availability in mammals, including angiogenesis, erythropoiesis and glycolysis. This gene was mapped to...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1, Anti-ARNT-interacting... |
| Anwendung: | WB, Direct ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
755,00 €
GN44028
Artikelnummer: Cay37289-1
GN44028 is an inhibitor of HIF-1alpha transcriptional activity. It reduces HIF-1alpha reporter gene expression in HeLa cervical cancer cells (IC50 = 14 nM). GN44028 induces cytotoxicity in HCT116 colorectal, HepG2 hepatic, PC3 prostate, and HeLa cancer cells (IC50s = 2.1, 3.7, 25.4, and 2.1 µM, respectively). It...
| Schlagworte: | N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,4-dihydro-indeno[1,2-c]pyrazol-3-amine |
| Anwendung: | HIF-1alpha transcriptional activity inhibitor |
| CAS | 1421448-26-1 |
| MW: | 305.3 D |
ab 68,00 €
Human HIF1a (Hypoxia Inducible Factor 1 Alpha) ELISA Kit
Artikelnummer: ELK-ELK1603.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human HIF1a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human HIF1a. Next,...
| Schlagworte: | BHLHE78, bHLHe78, HIF1-alpha, HIF-1-alpha, Member of PAS protein 1, ARNT-interacting protein, PAS domain-containing... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Rat HIF1a (Hypoxia Inducible Factor 1 Alpha) ELISA Kit
Artikelnummer: ELK-ELK1604.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat HIF1a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat HIF1a. Next,...
| Schlagworte: | Hif1a, HIF1-alpha, HIF-1-alpha, Hypoxia-inducible factor 1-alpha |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 365,00 €
Mouse HIF1a (Hypoxia Inducible Factor 1 Alpha) ELISA Kit
Artikelnummer: ELK-ELK1605.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse HIF1a. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse HIF1a. Next,...
| Schlagworte: | Hif1a, HIF1-alpha, HIF-1-alpha, ARNT-interacting protein, Hypoxia-inducible factor 1-alpha |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Anti-HIF-1alpha
Artikelnummer: ELK-EA095.100
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a protein that in humans is encoded by the HIF1A gene. HIF-1-alpha found in mammalian cells growing at low oxygen concentrations. It plays an essential role in cellular and systemic responses to hypoxia. Protein function: Functions as a master...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1, Anti-ARNT-interacting... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
Anti-HIF-1alpha
Artikelnummer: ELK-EA335.50
Hypoxia-inducible factor 1-alpha, also known as HIF-1-alpha, is a protein that in humans is encoded by the HIF1A gene. HIF-1-alpha found in mammalian cells growing at low oxygen concentrations. It plays an essential role in cellular and systemic responses to hypoxia. Protein function: Functions as a master...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1, Anti-ARNT-interacting... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
Anti-HIF-1 alpha
Artikelnummer: ARG43824.100
Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-bHLHe78, Anti-ARNT-interacting protein, Anti-ARNT-interacting protein, Anti-PAS... |
| Anwendung: | ELISA, ICC, IF, IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
624,00 €
Anti-HIF-1 alpha
Artikelnummer: ARG67073.100
Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein...
| Schlagworte: | Anti-BHLHE78, Anti-bHLHe78, Anti-bHLHe78, Anti-ARNT-interacting protein, Anti-ARNT-interacting protein, Anti-PAS... |
| Anwendung: | ELISA, ICC, IF, IHC (paraffin), WB |
| Wirt: | Mouse |
624,00 €
Anti-HIF1-alpha
Artikelnummer: A300-286A
Protein function: Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein...
| Schlagworte: | Anti-HIF1A, Anti-bHLHe78, Anti-BHLHE78, Anti-HIF1-alpha, Anti-HIF-1-alpha, Anti-Member of PAS protein 1,... |
| Anwendung: | WB, IP, IHC, ICC-IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 164,00 €
PX-478
Artikelnummer: Cay10005189-5
PX-478 suppresses both constitutive and hypoxia-induced levels of HIF-1alpha in cancer cells, resulting in reduced expression of HIF-1alpha target genes. It induces apoptosis in human tumor xenografts in mice to an extent that is proportional to initial HIF-1alpha level. PX-478 can also increase chemo- or...
| Schlagworte: | 4-[bis(2-chloroethyl)oxidoamino]-L-phenylalanine, dihydrochloride |
| Anwendung: | HIF-1 alpha inhibitor |
| CAS | 685898-44-6 |
| MW: | 394.1 D |
ab 89,00 €