Zu "K08203" wurden 27 Artikel gefunden!
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Probenecid
Artikelnummer: Cay14981-10
Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) and the ATP-binding cassette transporter (ABCC1) multidrug resistance protein 1 (MRP1) and activates the transient receptor potential (TRP) channel TRPV2. It inhibits OAT1, OAT3, and OAT6 (Kis = 6.3, 9.0, and 8.4 µM,...
| Schlagworte: | NSC 18786, 4-[(dipropylamino)sulfonyl]-benzoic acid |
| Anwendung: | Uricosuric, organic anion transporter inhibitor |
| CAS | 57-66-9 |
| MW: | 285.4 D |
ab 43,00 €
Steviol
Artikelnummer: Cay10011344-10
Steviol is the aglycon derivative of steviol glycosides, which are natural sweeteners isolated from S. rebaudiana. Steviol inhibits human organic anion transporters (hOATs) in uptake assays using murine cells from the S2 segment of proximal tubules. It is selective for hOAT1 and hOAT3 over hOAT2 and hOAT4 (IC50s =...
| Schlagworte: | Hydroxy Dehydrostevic Acid, NSC 226902, (4alpha)-13-hydroxy-kaur-16-en-18-oic acid |
| Anwendung: | OAT1 / OAT3 inhibitor |
| CAS | 471-80-7 |
| MW: | 318.5 D |
ab 115,00 €
4-Aminohippuric Acid
Artikelnummer: Cay23726-5
4-Aminohippuric acid is a substrate for various renal transporters that has been used in the study of anion uptake in the kidney. It is a substrate for organic anion transporter 1 (OAT1, Km = 14.3 µM in X. laevis oocytes), the human inorganic phosphate transporter (NPT1, Km = 2.66 mM in HEK293 cells), and apical...
| Schlagworte: | p-Aminohippuric Acid, para-Aminohippuric Acid, NSC 13064, NSC 7550, N-(4-aminobenzoyl)-glycine |
| Anwendung: | Renal transporter substrate |
| CAS | 61-78-9 |
| MW: | 194.2 D |
ab 50,00 €
4-Hydroxyhippuric Acid
Artikelnummer: Cay30115-100
4-Hydroxyhippuric Acid is a dihydroxy phenolic acid inhibitor of organic anion transporter 1 (OAT1, IC50 = 25 µM in opossum kidney cells). It increases the production of free radicals in opossum kidney cells expressing human OAT1. 4-Hydroxyhippuric Acid reduces the secretion of TNF-alpha, but not IL-1beta or IL-6,...
| Schlagworte: | para-Hydroxyhippuric Acid, 4-Hydroxyhippuric Acid, N-(4-hydroxybenzoyl)-glycine |
| Anwendung: | OAT1 inhibitor |
| CAS | 2482-25-9 |
| MW: | 195.2 D |
ab 50,00 €
Anti-SLC22A6
Artikelnummer: E-AB-16016.20
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have...
| Schlagworte: | Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 71,00 €
Anti-SLC22A6
Artikelnummer: NSJ-R30768
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Solute carrier family 22 (organic anion transporter), member 6, also called OAT1 or PAHT, is a protein that in humans is encoded by the SLC22A6 gene, which is also a member of the organic anion transporter (OAT) family of proteins. It is a transmembrane protein...
| Schlagworte: | Anti-OAT1, Anti-hOAT1, Anti-hPAHT, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
755,00 €
Anti-SLC22A6
Artikelnummer: E-AB-12825.120
The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have...
| Schlagworte: | Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,... |
| Anwendung: | WB, IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 71,00 €
Probenecid-d14
Artikelnummer: Cay26787-5
Probenecid-d14 is intended for use as an internal standard for the quantification of probenecid (Cay-14981) by GC- or LC-MS. Probenecid is a benzoic acid derivative that inhibits organic anion transporters (OATs) but activates the transient receptor potential (TRP) channel TRPV2. It inhibits OAT1, OAT3, and OAT6...
| Schlagworte: | 4-[[di(propyl-1,1,2,2,3,3,3-d7)amino]sulfonyl]-benzoic acid |
| Anwendung: | GC-MS, LC-MS, Quantification, Internal standard, Uricosuric, Organic anion transporter inhibitor |
| CAS | 1189657-87-1 |
| MW: | 299.4 D |
ab 195,00 €
Rebaudioside D
Artikelnummer: Cay27880-10
Rebaudioside D is a natural non-caloric sweetener. It is a steviol glycoside that has been found in S. rebaudiana leaves. Rebaudioside D, similarly to rebaudioside A (Cay-11894) and rebaudioside C (Cay-11895), is metabolized by gut microbiota to steviol (Cay-10011344), a compound whose safety is widely...
| Schlagworte: | (4alpha)-13-[(O-beta-D-glucopyranosyl-(1->2)-O-[beta-D-glucopyranosyl-(1->3)]-beta-D-glucopyranosyl)oxy]-kaur-16-en-18-oic... |
| Anwendung: | Natural non-caloric sweetener |
| CAS | 63279-13-0 |
| MW: | 1129.2 D |
ab 82,00 €
Anti-SLC22A6 / OAT1
Artikelnummer: ARG41225.50
Protein function: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the...
| Schlagworte: | Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
520,00 €
Anti-SLC22A6 / OAT1
Artikelnummer: ARG66609.100
Protein function: Involved in the renal elimination of endogenous and exogenous organic anions. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate, ketoglutarate, etc). Mediates the...
| Schlagworte: | Anti-OAT1, Anti-hPAHT, Anti-hOAT1, Anti-hROAT1, Anti-SLC22A6, Anti-PAH transporter, Anti-Organic anion transporter 1,... |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
584,00 €
Anti-SLC22A6
Artikelnummer: G-CAB3184.100
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 352,00 €