Zu "K08179" wurden 49 Artikel gefunden!
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Anti-SLC16A1 / Monocarboxylate transporter 1 / MCT1,...
Artikelnummer: NSJ-RQ8882
Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA. SLC16A1 (also called Monocarboxylate transporter 1 and MCT1) is a 12-transmembrane monocarboxylate/proton symporter that mediates bidirectional transport of lactate, pyruvate, and ketone bodies across the plasma membrane. Coupled to H+...
| Schlagworte: | Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1, SLC16A1 Antibody /... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
Anti-Recombinant SLC16A1, clone A653
Artikelnummer: E-AN301937L.100
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants...
| Schlagworte: | Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1, Recombinant SLC16A1 Monoclonal... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat |
ab 304,00 €
AZD 3965
Artikelnummer: Cay19912-1
AZD 3965 is a potent inhibitor of monocarboxylate transporter 1 (MCT1, Ki = 1.6 nM), killing tumor cells that are reliant on glycolysis by blocking lactate transport. It displays six-fold selectivity for MCT1 over MCT2 and is without effect against MCT4 at 10 µM. AZD 3965 increases intratumor lactate levels and...
| Schlagworte: | 5-[[(4S)-4-hydroxy-4-methyl-2-isoxazolidinyl]carbonyl]-3-methyl-1-(1-methylethyl)-6-[[5-methyl-3-(trifluoromethyl)-1H-pyra... |
| Anwendung: | SLC16A1 inhibitor |
| CAS | 1448671-31-5 |
| MW: | 515.5 D |
ab 72,00 €
7ACC2
Artikelnummer: Cay23445-5
7ACC2 is a carboxycoumarin inhibitor of monocarboxylate transporter 1 (MCT1) with an IC50 value of 10 nM for lactate uptake, an MCT1-dependent process, in SiHa human cervix carcinoma cells. It inhibits proliferation of SiHa cells in the presence of lactate in a dose-dependent manner but lacks cytotoxicity in the...
| Schlagworte: | 7-[methyl(phenylmethyl)amino]-2-oxo-2H-1-benzopyran-3-carboxylic acid |
| Anwendung: | SLC16A1 / MCT1 inhibitor |
| CAS | 1472624-85-3 |
| MW: | 309.3 D |
ab 49,00 €
AR-C 155858
Artikelnummer: Cay14884-1
AR-C 155858 is an inhibitor of monocarboxylate transporter 1 (MCT1) and MCT2 (Kis = 2.3 and Xenopus oocytes expressing the human receptors). It is selective for MCT1 and MCT2 over MCT4 (Ki = >10 µM). AR-C 155858 inhibits L-lactate uptake in and proliferation of murine 4T1 breast cancer cells (IC50s = 25 and 20.2 nM,...
| Schlagworte: | 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-thieno[... |
| Anwendung: | Monocarboxylate transporter 1/2 inhibitor |
| CAS | 496791-37-8 |
| MW: | 461.5 D |
360,00 €
alpha-Cyano-4-hydroxycinnamic acid
Artikelnummer: AG-CR1-3686-G001
Specific monocarboxylate transporter (MCT) inhibitor. Inhibits mitochondrial lactate and pyruvate transport. Decreases glycolysis. Useful agent for immunometabolism research. Exhibits antitumoral and antiangiogenic activity in gliomas in vivo, decreases glycolytic metabolism, migration and invasion. Blocks lactate...
| Schlagworte: | alpha-Cyano-4-hydroxycinnamate, alpha-CCA, 4-HCCA, CHCA, NSC173138 |
| Anwendung: | Specific monocarboxylate transporter (MCT) inhibitor |
| CAS | 28166-41-8 |
| MW: | 189.2 D |
50,00 €
alpha-Cyano-4-hydroxycinnamic Acid
Artikelnummer: Cay15254-1
alpha-Cyano-4-hydroxycinnamic acid (alpha-CHCA) is an inhibitor of monocarboxylate transporter 1 (MCT1) that blocks pyruvate transport in rat heart mitochondria (IC50 = 1.5 µM). It is commonly used as a matrix to facilitate peptide ionization in matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF)...
| Schlagworte: | CHC, NSC 173138, alpha-CHCA, 2-cyano-3-(4-hydroxyphenyl)-2-propenoic acid |
| Anwendung: | Monocarboxylate transporter 1 (MCT1) inhibitor |
| CAS | 28166-41-8 |
| MW: | 189.2 D |
ab 54,00 €
Anti-MCT1
Artikelnummer: A304-357A
Protein function: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate....
| Schlagworte: | Anti-MCT1, Anti-MCT 1, Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1 |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-MCT1
Artikelnummer: A304-358A
Protein function: Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate....
| Schlagworte: | Anti-MCT1, Anti-MCT 1, Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1 |
| Anwendung: | WB, IP, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Mouse Slc16a1 / Monocarboxylate transporter 1 ELISA Kit
Artikelnummer: G-MOFI00598.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-SLC16A1
Artikelnummer: NSJ-F48179-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. SLC16A1 is a monocarboxylate transporter (MCT1) that mediates the movement of lactate and pyruvate across cell membranes. Import and export of these substrates by tissues such as erythrocytes, muscle, intestine, and kidney are ascribed largely to the action of a...
| Schlagworte: | Anti-MCT1, Anti-MCT 1, Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1, SLC16A1... |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-SLC16A1
Artikelnummer: E-AB-15768.120
The protein encoded by this gene is a proton-linked monocarboxylate transporter that catalyzes the movement of many monocarboxylates, such as lactate and pyruvate, across the plasma membrane. Mutations in this gene are associated with erythrocyte lactate transporter defect. Alternatively spliced transcript variants...
| Schlagworte: | Anti-MCT1, Anti-MCT 1, Anti-SLC16A1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1, SLC16A1... |
| Anwendung: | IHC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 89,00 €