Zu "K08155" wurden 64 Artikel gefunden!
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Reserpine
Artikelnummer: Cay16474-1
Reserpine is an alkaloid isolated from dried roots of R. serpentine, which is used in traditional Indian medicine. Reserpine irreversibly inhibits both human isoforms of vesicular monoamine transporter, VMAT1 and VMAT2 (Kis = 34 and 12 nM, respectively). As this leads to metabolism of monoamines, reserpine is used...
| Schlagworte: | NSC 237659, NSC 59272, Rausedil,... |
| Anwendung: | Irreversible vesicular monoamine transporter (VMAT) inhibitor |
| CAS | 50-55-5 |
| MW: | 608.7 D |
ab 49,00 €
NBI 98782
Artikelnummer: Cay42116-10
Solulibility: DMSO: Sparingly Soluble: 1-10 mg/ml: Ethanol: Sparingly Soluble: 1-10 mg/ml.
| Schlagworte: | alpha-Dihydrotetrabenazine, alpha-DTBZ,... |
| Anwendung: | VMAT2 inhibitor |
| CAS | 85081-18-1 |
| MW: | 319.44 D |
ab 186,00 €
Decynium-22
Artikelnummer: Cay29494-250
Decynium-22 is an inhibitor of monoamine transporters and organic cation transporters (OCTs). It inhibits the plasma membrane monoamine, serotonin (5-HT), norepinephrine, and dopamine monoamine transporters (IC50s = 1.1, 7.9, 30, and 12.9 µM, respectively), and OCT2 and OCT3 (IC50s = 10 and 0.2 µM, respectively) in...
| Schlagworte: | 1,1'-Diethyl-2,2'-Cyanine, 1-ethyl-2-[(1-ethyl-2(1H)-quinolinylidene)methyl]-quinolinium, monoiodide |
| Anwendung: | Monoamine transporter / OCT inhibitor |
| CAS | 977-96-8 |
| MW: | 454.4 D |
ab 73,00 €
Tetrabenazine
Artikelnummer: Cay20380-10
Tetrabenazine is an inhibitor of vesicular monoamine transporter 2 (VMAT2) that is selective over VMAT1 (Kis = 97 and >20,000 nM, respectively, in a serotonin uptake assay). It dose-dependently reduces levels of the monoamines norepinephrine (Cay-16673), dopamine (Cay-21992), and serotonin (5-HT, Cay-14332) in rat...
| Schlagworte: | NSC 169886, NSC 172187, Ro 1-9569, TBZ,... |
| Anwendung: | Neuroleptic, catecholamine uptake inhibitor |
| CAS | 58-46-8 |
| MW: | 317.4 D |
ab 49,00 €
FFN-102 (trifluoroacetate salt)
Artikelnummer: Cay21458-1
FFN-102 is a fluorescent false neurotransmitter (FFN) that is a substrate for the dopamine transporter (DAT) and vesicular monoamine transporter 2 (VMAT2). It is a pH-dependent fluorescent probe that labels dopamine cell bodies, axons, and presynaptic terminals. It can also be used to monitor dopamine exocytosis. It...
| Schlagworte: | 4-(2-aminoethyl)-6-chloro-7-hydroxy-2H-1-benzopyran-2-one 2,2,2-trifluoroacetate |
| Anwendung: | pH responsive fluorescent false neurotransmitter, DAT substrate, VMAT2 substrate |
| CAS | 1234064-11-9 |
| MW: | 353.7 D |
ab 50,00 €
Anti-SLC18A1
Artikelnummer: ATA-HPA063797.100
Protein function: Involved in the transport of biogenic monoamines, such as serotonin, from the cytoplasm into the secretory vesicles of neuroendocrine and endocrine cells. [The UniProt Consortium] Buffer: 40% glycerol and PBS (pH 7.2). 0.02% sodium azide is added as preservative. Highest antigen sequence identity...
| Schlagworte: | Anti-VAT1, Anti-SLC18A1, Anti-Vesicular amine transporter 1, Anti-Solute carrier family 18 member 1, Anti-Chromaffin... |
| Anwendung: | IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 330,00 €
Anti-VMAT2 / SLC18A2, C-terminal
Artikelnummer: ARG63687.100
Protein function: Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. [The UniProt Consortium]
| Schlagworte: | Anti-SVMT, Anti-VAT2, Anti-SLC18A2, Anti-Monoamine transporter, Anti-Vesicular amine transporter 2, Anti-Solute carrier... |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Mouse Slc18a1 / Solute Carrier Family 18,Member 1 ELISA Kit
Artikelnummer: G-MOFI01115.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Mouse Slc18a2 / Solute Carrier Family 18,Member 2 ELISA Kit
Artikelnummer: G-MOFI01116.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €
Anti-Vesicular Monoamine Transporter 2 (VMAT2)
Artikelnummer: 600-601-D00
Anti-Vesicular Monoamine Transporter 2 antibody was affinity purified from monospecific antiserum by immunoaffinity purification. Anti-Vesicular Monoamine Transporter 2 Antibody is directed against rat Vesicular Monoamine Transporter 2. Cross reactivity with Vesicular Monoamine Transporter 2 from other species has...
| Schlagworte: | Anti-SVMT, Anti-VAT2, Anti-SLC18A2, Anti-Monoamine transporter, Anti-Vesicular amine transporter 2, Anti-Solute carrier... |
| Anwendung: | ELISA, WB |
| Wirt: | Sheep |
| Spezies-Reaktivität: | rat |
877,00 €
Anti-VMAT2
Artikelnummer: NSJ-R36117-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Vesicular monoamine transporter 2, solute carrier family 18 (vesicular monoamine) member 2 (SLC18A2) Protein function: Involved in the ATP-dependent vesicular transport of biogenic amine...
| Schlagworte: | Anti-SVMT, Anti-VAT2, Anti-SLC18A2, Anti-Monoamine transporter, Anti-Vesicular amine transporter 2, Anti-Solute carrier... |
| Anwendung: | WB, IHC, ELISA (peptide), IHC (paraffin) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
836,00 €
Dihydrotetrabenazine
Artikelnummer: Cay27182-1
Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine (Cay-20380) that is generated by hepatic carbonyl reductases. Dihydrotetrabenazine binds to mouse pons medulla, hypothalamus, and striatum (Kds = 2.72, 2.28, and 2.4 nM, respectively) and inhibits...
| Schlagworte: | trans-(2,3)-Dihydro Tetrabenazine, DTBZ, 1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-ol |
| Anwendung: | Active metabolite, VMAT2 inhibitor |
| CAS | 3466-75-9 |
| MW: | 319.4 D |
ab 181,00 €