Zu "K07835" wurden 39 Artikel gefunden!
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BQU57
Artikelnummer: Cay16960-5
BQU57 is an inhibitor of the Ras-like GTPases RalA and RalB. It binds to RalB when RalB is bound to GDP with a Kd value of 7.7 µM, as determined by isothermal titration calorimetry (ITC). BQU57 (10 µM) decreases RalA and RalB activity in H2122 and H358 cells. It also inhibits colony formation of Ral-dependent H2122...
| Schlagworte: | 6-amino-1,4-dihydro-1,3-dimethyl-4-[4-(trifluoromethyl)phenyl]-pyrano[2,3-c]pyrazole-5-carbonitrile |
| Anwendung: | RalA / RalB inhibitor |
| CAS | 1637739-82-2 |
| MW: | 334.3 D |
ab 53,00 €
RBC8
Artikelnummer: Cay21281-5
RBC8 is a small molecule inhibitor of the Ras-like GTPases RalA and RalB that prevents binding of the GTPase to the Ral-binding protein. RBC8 has been shown to prevent Ral-mediated spreading of murine embryonic fibroblasts, block anchorage-independent growth of H2122 and H358 lung cancer cell lines (IC50s = 3.5 and...
| Schlagworte: | 6-amino-4-(2,5-dimethoxyphenyl)-1,4-dihydro-3-(2-naphthalenyl)-pyrano[2,3-c]pyrazole-5-carbonitrile |
| Anwendung: | RalA / RalB inhibitor |
| CAS | 361185-42-4 |
| MW: | 424.5 D |
ab 59,00 €
Anti-RALB
Artikelnummer: ARG56332.100
Protein function: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for...
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-RALB
Artikelnummer: NSJ-R31944
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Ras-related protein Ral-B (RalB) is a protein that in humans is encoded by the RALB gene on chromosome 2. This protein is one of two isoforms of the Ral protein, the other being RalA, and part of the Ras GTPase family. As a Ras GTPase, RalB functions as a...
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B, RALB Antibody |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-RalB
Artikelnummer: NB-21033
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. The Ras-like small G proteins, RalA/B, are important components of Ras signaling pathways, implicated in the initiation and maintenance of tumorigenic transformation, as well as vesicle transport, apoptosis,...
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | vertebrates |
355,00 €
Anti-RalB, monoclonal
Artikelnummer: NB-26018
Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. The Ras-like small G proteins, RalA/B, are important components of Ras signaling pathways, implicated in the initiation and maintenance of tumorigenic transformation, as well as vesicle transport, apoptosis,...
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B |
| Anwendung: | ELISA, WB, IP, IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | vertebrates |
369,00 €
Ras-related protein Ral-B (RALB), human, recombinant
Artikelnummer: CSB-EP019297HU.1
Organism: Homo sapiens (Human). Source: E.coli. Expression Region: 1-206aa. Protein Length: Full Length. Tag Info: N-terminal GST-tagged. Target Protein Sequence: MAANKSKGQS SLALHKVIMV GSGGVGKSAL TLQFMYDEFV EDYEPTKADS YRKKVVLDGE EVQIDILDTA GQEDYAAIRD NYFRSGEGFL LVFSITEHES FTATAEFREQ ILRVKAEEDK IPLLVVGNKS DLEERRQVPV...
| Schlagworte: | RALB, Ras-related protein Ral-B, Recombinant Human Ras-related protein Ral-B (RALB) |
| Anwendung: | Activity not tested |
| Exprimiert in: | E.coli |
| Ursprungsart: | human |
| MW: | 50.1 kD |
ab 219,00 €
Anti-RALB
Artikelnummer: CSB-PA219431.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RALB. Antigen Species: Human
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B, 5730472O18Rik antibody, dRalb antibody, GTP binding protein antibody, Ralb... |
| Anwendung: | ELISA, WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
Anti-RALB
Artikelnummer: CSB-PA283609.100
Host Species: Rabbit. Isotype: IgG. Buffer: -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antigen affinity purification. Target Name: RALB. Antigen Species: Human
| Schlagworte: | Anti-RALB, Anti-Ras-related protein Ral-B, 5730472O18Rik antibody, dRalb antibody, GTP binding protein antibody, Ralb... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 167,00 €
BQU57
Artikelnummer: TGM-T2267-100mg
Description: BQU57 selectively inhibits Ral over Ras or Rho and suppresses xenograft tumor growth. Target: GTPase, Ras. Smiles: Cc1nn(C)c2OC(N)=C(C#N)C(c12)c1ccc(cc1)C(F)(F)F
| Anwendung: | RalA / RalB inhibitor |
| CAS | 1637739-82-2 |
| MW: | 334.3 D |
ab 33,00 €
RBC8
Artikelnummer: TGM-T6634-100mg
Description: RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras. Target: Ras, GTPase. Smiles: COc1ccc(OC)c(c1)C1c2c(OC(N)=C1C#N)[nH]nc2-c1ccc2ccccc2c1. References: Yan C, et al. Nature. 2014, 515(7527), 443-447.
| Anwendung: | RalA / RalB inhibitor |
| CAS | 361185-42-4 |
| MW: | 424.45 D |
ab 39,00 €
Anti-RALB
Artikelnummer: ABS-KC-1065.100
Protein function: Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for...
| Schlagworte: | Anti-Ras-related protein Ral-B, RALB Antibody |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €