Zu "K07828" wurden 66 Artikel gefunden!
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Erastin
Artikelnummer: Cay17754-5
Erastin, named for eradicator of RAS and small T (ST) antigen-expressing cells, is a ferroptosis inducer. It induces ferroptotic cell death in vitro, an effect that can be blocked by the ferroptosis inhibitors ciclopirox olamine, Trolox (Cay-10011659), ferrostatin-1 (Cay-17729), U-0126 (Cay-70970), cycloheximide...
| Schlagworte: | 2-[1-[4-[2-(4-chlorophenoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone |
| Anwendung: | Antitumor agent |
| CAS | 571203-78-6 |
| MW: | 547.1 D |
ab 73,00 €
NRAS, His, Human
Artikelnummer: GSC-Z05709-100
NRas is a key mediator of the mitogenic pathway in normal cells and in cancer cells. Its dynamics and nanoscale organization at the plasma membrane (PM) facilitate its signaling. NRas activity is mediated and regulated by its dynamic interactions with functional (Grb2, BRAF, NF1, and GPI-nucleated) clusters at the PM.
| Schlagworte: | NRAS, GTPase NRas, Transforming protein N-Ras |
| Ursprungsart: | human |
| MW: | 22.29 kD |
ab 497,00 €
Anti-NRAS/N-Ras Monoclonal Antibody
Artikelnummer: E-AN200076P.100
This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine...
| Schlagworte: | NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras, NRAS/N-Ras Monoclonal Antibody |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
389,00 €
NRAS (Q61L), His-Tag
Artikelnummer: BPS-100801
Human NRAS, also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61L mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.
| Schlagworte: | NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras, |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
483,00 €
NRAS (Q61K), His-Tag
Artikelnummer: BPS-100800-1
Human NRAS, also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61K mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.
| Schlagworte: | NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras, |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
ab 498,00 €
Farnesyl Thiosalicylic Acid Amide
Artikelnummer: Cay13175-10
Association of Ras protein with the inner surface of the plasma membrane is required for Ras signaling activity. Farnesyl thiosalicylic acid (FTS) amide is an FTS derivative with an amide added to the carboxyl group. FTS amide inhibits the growth of PANC-1 and U87 tumor cells with IC50 values of 20 and 10 µM,...
| Schlagworte: | FTS Amide, Salirasib Amide, 2-[[(2E,6E)-3,7,11-trimethyl-2,6,10-dodecatrien-1-yl]thio]-benzamide |
| Anwendung: | Ras signaling inhibitor |
| CAS | 1092521-74-8 |
| MW: | 357.6 D |
ab 29,00 €
NRAS (Q61H), His-Tag
Artikelnummer: BPS-100799
Human NRAS also known as GTPase NRas and NS6, GenBank Accession No. NM_002524, a.a. 2-186, with Q61H mutation and N-terminal His-tag, expressed in a Baculovirus infected Sf9 cell expression system. MW=22 kDa.
| Schlagworte: | NRAS, HRAS1, GTPase NRas, Transforming protein N-Ras, |
| Anwendung: | Ras signaling studies |
| Exprimiert in: | insect cells |
| Ursprungsart: | human |
| MW: | 22 kD |
483,00 €
Anti-N-Ras, clone 822CT17.5.1
Artikelnummer: ARG55671.100
Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras |
| Anwendung: | WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat |
616,00 €
Anti-N-Ras
Artikelnummer: ARG55695.100
Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras |
| Anwendung: | IHC (paraffin), FC, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-Ras (pan), clone 2G9
Artikelnummer: ARG57108.50
Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras |
| Anwendung: | WB, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
518,00 €
Anti-NRAS, Internal
Artikelnummer: ARG64621.100
Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras |
| Anwendung: | ELISA, IHC (paraffin), WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
871,00 €
Anti-NRAS
Artikelnummer: NSJ-R35682-100UG
0.5 mg/ml in 1X TBS, pH7.3, with 0.5% BSA (US sourced) and 0.02% sodium azide. Additional name(s) for this target protein: Neuroblastoma RAS Protein function: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. [The UniProt Consortium]
| Schlagworte: | Anti-NRAS, Anti-HRAS1, Anti-GTPase NRas, Anti-Transforming protein N-Ras, NRAS Antibody |
| Anwendung: | WB, IHC, ELISA (peptide) |
| Wirt: | Goat |
| Spezies-Reaktivität: | human, rat |
836,00 €