Zu "K07759" wurden 42 Artikel gefunden!
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NEU
Enzolution(R) PARG Assay System
Artikelnummer: BBL-3033-10K
The Enzolution(R) PARG Assay System is intended for use with the Transcreener(R) ADPR FP Assay Kit (Part #3030) to measure enzymatic activity for PARG (poly(ADP-ribose) glycohydrolase). PARG produces ADPR from the breakdown of poly(ADP-ribose) (polyADPR). It plays an important role in DNA damage repair and has been...
| Schlagworte: | PARG, Poly(ADP-ribose) glycohydrolase |
| Anwendung: | HTS, drug discovery, enzyme assays |
ab 1.127,00 €
NEU
Recombinant PARG Enzyme, Active, Human
Artikelnummer: BBL-2283
Active, full-length (aa 1-976), human poly(ADP-Ribose) glycohydrolase (PARG) enzyme, C-terminal 6xHis-tagged protein expressed and purified from Baculovirus-infected insect cells. The enzyme has been thoroughly validated with Transcreener ADPR Activity Assays. For specific activity, please refer to the Certificate...
| Schlagworte: | PARG, Poly(ADP-ribose) glycohydrolase |
| Anwendung: | HTS, drug discovery, enzyme assays |
| Exprimiert in: | Insect cells |
| Ursprungsart: | human |
ab 341,00 €
Anti-PARG / Poly(ADP-ribose) glycohydrolase
Artikelnummer: NSJ-FY12283
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. PARG antibody detects Poly(ADP-ribose) glycohydrolase, encoded by the PARG gene on chromosome 10q11.23. PARG antibody is widely used in DNA damage response, chromatin remodeling, and cancer biology research. PARG is the main enzyme responsible...
| Schlagworte: | Anti-PARG, Anti-Poly(ADP-ribose) glycohydrolase, PARG Antibody / Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB, ICC/IF, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
PARG Inhibitor PDD00017273
Artikelnummer: AG-CR1-3646-M001
White to off-white solid. Soluble in DMSO, methanol or acetonitrile. Human poly(ADP-ribose) glycohydrolase (PARG) inhibitor for in vitro studies, Inhibits human recombinant PARG enzymes (IC50=26nM) and PARG in cell assays (IC50=37nM). Inactive against related glycohydrolases ARH3 and PARP1s (IC50>,30µ,M)....
| Schlagworte: | PARG Inhibitor Compound 4,... |
| Anwendung: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514,6 D |
ab 72,00 €
Anti-PARG
Artikelnummer: A305-405A
Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...
| Schlagworte: | Anti-PARG, EC=3.2.1.143, Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PARG
Artikelnummer: A305-410A
Protein function: Poly(ADP-ribose) synthesized after DNA damage is only present transiently and is rapidly degraded by poly(ADP-ribose) glycohydrolase (PubMed:23102699). PARG acts both as an endo- and exoglycosidase, releasing PAR of different length as well as ADP- ribose monomers (PubMed:23102699). Required for...
| Schlagworte: | Anti-PARG, EC=3.2.1.143, Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 165,00 €
Anti-PARG
Artikelnummer: ARG40973.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
616,00 €
Anti-PARG
Artikelnummer: ARG41050.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP-ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as ADP-...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
707,00 €
PDD00017273
Artikelnummer: Cay19511-1
PDD00017273 is a poly(ADP-ribose) glycohydrolase (PARG) inhibitor (IC50 = 26 nM in an enzyme assay). It maintains persistence of nuclear PAR chains in HeLa cells induced by the DNA damaging agent methylmethanesulfonate (MMS, IC50 = 37 nM). PDD00017273, in combination with MMS, increases nuclear phosphorylated H2AX...
| Schlagworte: | 1-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-1,2,3,4-tetrahydro-N-(1-methylcyclopropyl)-3-[(2-methyl-5-thiazolyl)methyl]-2,4-d... |
| Anwendung: | PARG inhibitor |
| CAS | 1945950-21-9 |
| MW: | 514.6 D |
ab 69,00 €
Anti-PARG
Artikelnummer: ATA-HPA021819.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP- ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | ICC, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
Anti-PARG
Artikelnummer: ATA-HPA053007.100
Protein function: Poly(ADP-ribose) glycohydrolase that degrades poly(ADP- ribose) by hydrolyzing the ribose-ribose bonds present in poly(ADP- ribose) (PubMed:21892188, PubMed:23102699, PubMed:23474714). PARG acts both as an endo- and exoglycosidase, releasing poly(ADP-ribose) of different length as well as...
| Schlagworte: | Anti-Poly(ADP-ribose) glycohydrolase |
| Anwendung: | ICC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 246,00 €
PARG, His-Tag Recombinant
Artikelnummer: BPS-101726
Recombinant human PARG (Poly(ADP-ribose) glycohydrolase), full length encompassing amino acids 2-976 (end). The construct contains an N-terminal His-Tag (6xHis). The recombinant protein was affinity purified.
| Schlagworte: | Poly(ADP-ribose) glycohydrolase, PARG (His-2-976(end)) |
| Anwendung: | Enzyme kinetics, inhibitor screening, selectivity profiling |
| Ursprungsart: | human |
819,00 €