Zu "K07434" wurden 71 Artikel gefunden!
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Anti-Zebrafish Cyp19a1b / Aromatase
Artikelnummer: NSJ-RZ1215
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cyp19a1b, or cytochrome P four five zero family nineteen subfamily A polypeptide one b, is an aromatase enzyme that catalyzes the conversion of androgens into estrogens. In zebrafish, Cyp19a1b is the brain-specific isoform of aromatase and plays a key role in...
| Schlagworte: | Anti-AroB, Anti-cyp19, Anti-cyp19b, Anti-CYP19a2, Anti-cyp19a1b, Anti-P450aromB, Anti-aromatase, Anti-zgc:92614,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | zebrafish |
948,00 €
Aminoglutethimide
Artikelnummer: Cay20947-1
Aminoglutethimide is an aromatase inhibitor (IC50 = 7.5 µM). Aromatase inhibitors, including aminoglutethimide, inhibit estrogen synthesis via aromatase, suppressing estrogen levels in post-menopausal women. Formulations containing aromatase inhibitors have been used to treat estrogen receptor-positive breast cancer...
| Schlagworte: | DL-Aminoglutethimide, NSC 330915, 3-(4-aminophenyl)-3-ethyl-2,6-piperidinedione |
| Anwendung: | Aromatase inhibitor |
| CAS | 125-84-8 |
| MW: | 232.3 D |
ab 49,00 €
Exemestane
Artikelnummer: Cay15008-50
Exemestane is an irreversible inhibitor of aromatase (Ki = 26 nM). It is selective for aromatase over 5alpha-reductase when used at a concentration of 30 µM. Subcutaneous administration of exemestane (3-100 mg/kg per day) decreases tumor proliferation in rats with mammary tumors induced by the carcinogenic...
| Schlagworte: | Aromasin(TM), FCE 24304, 6-methylene-androsta-1,4-diene-3,17-dione |
| Anwendung: | Steroidal aromatase inhibitor |
| CAS | 107868-30-4 |
| MW: | 296.4 D |
ab 67,00 €
Anastrozole
Artikelnummer: Cay11987-10
Anastrozole is an aromatase/CYP19A1 inhibitor (IC50 = 15 nM for human placental aromatase/CYP19A1). It is selective for aromatase/CYP19A1 over the cytochrome P450 (CYP) isoforms CYP1A2, CYP2A6, CYP2C9, CYP2D6, and CYP3A (IC50s = 27-650 µM). Anastrozole (0.1 mg/kg) blocks ovulation in mature female rats and...
| Schlagworte: | Anastrol, ICI-D 1033, ZD 1033,... |
| Anwendung: | Aromatase inhibitor |
| CAS | 120511-73-1 |
| MW: | 293.4 D |
ab 85,00 €
Exemestane
Artikelnummer: LKT-E9317.25
A steroidal aromatase inhibitor.
| Schlagworte: | FCE-24304 |
| Anwendung: | Steroidal aromatase inhibitor |
| CAS | 107868-30-4 |
| MW: | 296,4 D |
ab 141,00 €
Anti-CYP19A1 / Aromatase, clone H4
Artikelnummer: ARG22848.250
Protein function: Catalyzes the formation of aromatic C18 estrogens from C19 androgens. [The UniProt Consortium]
| Schlagworte: | Anti-ARO1, Anti-CYPXIX, Anti-CYP19A1, Anti-Aromatase, Anti-Estrogen synthase, Anti-Cytochrome P450 19A1, Anti-Cytochrome... |
| Anwendung: | ICC, IF, IHC (paraffin), WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, rat, marmoset, chicken, mouse, swine, baboon, goat, bovine, horse, rabbit, sheep |
592,00 €
Letrozole
Artikelnummer: Cay11568-10
Letrozole is a potent, cell-permeable inhibitor of aromatase (IC50 = 2 nM). It inhibits proliferation of estrogen receptor-positive (ER+) MCF-7 cells when used alone at concentrations ranging from 0.1 to 100 nM and when used at a concentration of 10 nM in combination with testosterone or 4-androstene-3,17-dione. It...
| Schlagworte: | CGS 20267, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-benzonitrile |
| Anwendung: | Aromatase inhibitor, chemoprevention |
| CAS | 112809-51-5 |
| MW: | 285.3 D |
ab 67,00 €
Fadrozole (hydrochloride)
Artikelnummer: Cay24272-10
Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1.4 nM for human placental and rat ovarian microsomal aromatase, respectively). It selectively inhibits estrogen over progesterone production induced by luteinizing hormone (LH) in hamster ovarian tissue as well as corticosterone and aldosterone...
| Schlagworte: | CGS 16949A, 4-(5,6,7,8-tetrahydroimidazo[1,5-a]pyridin-5-yl)-benzonitrile, monohydrochloride |
| Anwendung: | Aromatase inhibitor |
| CAS | 102676-31-3 |
| MW: | 259.7 D |
ab 49,00 €
Anastrozole
Artikelnummer: LKT-A5302.100
Aromatase inhibitor.
| Schlagworte: | ZD1033 Pure, Zeneca ZD1033, 2,2'-(5-(IH-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropiononitrile) |
| Anwendung: | Aromatase inhibitor |
| CAS | 120511-73-1 |
| MW: | 293.37 D |
ab 126,00 €
Letrozole-d4
Artikelnummer: Cay26517-1
Letrozole-d4 is intended for use as an internal standard for the quantification of letrozole (Cay-11568) by GC- or LC-MS. Letrozole is a potent, cell-permeable inhibitor of aromatase (IC50 = 2 nM). It inhibits proliferation of estrogen receptor-positive (ER+) MCF-7 cells when used alone at concentrations ranging...
| Schlagworte: | 4-[(4-cyanophenyl)-1H-1,2,4-triazol-1-ylmethyl]-benzonitrile-2,3,5,6-d4 |
| Anwendung: | GC-MS, LC-MS, quantification, internal standard, aromatase inhibitor |
| CAS | 1133712-96-5 |
| MW: | 289.3 D |
ab 228,00 €
Anti-Aromatase / CYP19A1, Internal
Artikelnummer: ARG64444.100
Protein function: Catalyzes the formation of aromatic C18 estrogens from C19 androgens. [The UniProt Consortium]
| Schlagworte: | Anti-ARO1, Anti-CYPXIX, Anti-CYP19A1, Anti-Aromatase, EC=1.14.14.14, Anti-Estrogen synthase, Anti-Cytochrome P-450AROM,... |
| Anwendung: | ELISA, WB |
| Wirt: | Goat |
| Spezies-Reaktivität: | human |
871,00 €
Mouse Cyp19a1 / Cytochrome P450 19A1 ELISA Kit
Artikelnummer: G-MOFI00530.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
698,00 €