Zu "K07410" wurden 52 Artikel gefunden!
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Anti-CYP1B1 / Cytochrome P450 1B1
Artikelnummer: NSJ-FY12951
Adding 0.2 ml of distilled water will yield a concentration of 500 ug/ml. CYP1B1 antibody detects Cytochrome P450 1B1, a member of the cytochrome P450 superfamily of monooxygenases involved in xenobiotic metabolism, steroid synthesis, and carcinogen activation. The UniProt recommended name is Cytochrome P450 1B1...
| Schlagworte: | Anti-CYP1B1, Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, CYP1B1 Antibody /... |
| Anwendung: | WB, FC, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
790,00 €
4-Hydroxyestradiol
Artikelnummer: Cay31508-10
4-Hydroxyestradiol is a catechol estrogen and minor metabolite of estrogen. 4-Hydroxyestradiol is formed from estrogen by the cytochrome P450 (CYP) isoform CYP1B1. Production of 4-hydroxyestradiol is increased in microsomes prepared from human mammary adenocarcinoma and fibroadenoma microsomes compared with...
| Schlagworte: | 4-Hydroxy-17beta-estradiol, (17beta)-estra-1,3,5(10)-triene-3,4,17-triol |
| Anwendung: | Catechol estrogen, minor metabolite of estrogen |
| CAS | 5976-61-4 |
| MW: | 288.4 D |
ab 85,00 €
TMS
Artikelnummer: Cay10038-1
CYP1B1 is mainly an extrahepatic enzyme which oxidatively metabolizes both endogenous (steroids, eicosanoids) and exogenous xenobiotics such aspolyaromatic hydrocarbons. TMS is a potent and selective inhibitor of CYP1B1, with an IC50 of 6 nM. It is 50-fold selective for the inhibition of CYP1B1 versus CYP1A1, making...
| Schlagworte: | 2,3',4,5'-Tetramethoxystilbene, 1-[(1E)-2-(3,5-dimethoxyphenyl)ethenyl]-2,4-dimethoxy-benzene |
| Anwendung: | CYP1B1 inhibitor |
| CAS | 24144-92-1 |
| MW: | 300.4 D |
ab 25,00 €
Diosmetin
Artikelnummer: Cay18649-250
Diosmetin is a flavonoid that has been found in citrus fruits and has diverse biological activities. It inhibits the cytochrome P450 (CYP) isoforms CYP1A1 and CYP1B1 (Kis = 89 and 16 nM, respectively). Diosmetin prevents increases in erythrocyte reactive oxygen species (ROS) and malondialdehyde (MDA) levels induced...
| Schlagworte: | Diosmetol, Luteolin 4'-methyl ester, 5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4H-1-benzopyran-4-one |
| Anwendung: | CYP1A1 inhibitor, CYP1B1 inhibitor |
| CAS | 520-34-3 |
| MW: | 300.3 D |
ab 93,00 €
DMU2139
Artikelnummer: Cay37301-5
DMU2139 is an inhibitor of the cytochrome P450 (CYP) isoform CYP1B1 (IC50 = 0.009 µM). It is selective for CYP1B1 over CYP1A1, CYP1A2, CYP3A4, and CYP2D6 (IC50s = 0.795, 1.2, 10.6, and 5 µM, respectively). DMU2139 enhances cisplatin-induced cell death in HEK293 cells overexpressing CYP1B1.Formal Name:...
| Schlagworte: | 1-(6-methoxy-2-naphthalenyl)-3-(3-pyridinyl)-2-propen-1-one |
| Anwendung: | CYP1B1 inhibitor |
| CAS | 104890-70-2 |
| MW: | 289.3 D |
ab 122,00 €
Human CYP1B1 ELISA Kit
Artikelnummer: G-HUFI02373.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-CYP1B1
Artikelnummer: NSJ-R32253
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and...
| Schlagworte: | Anti-CYPIB1, Anti-Cytochrome P450 1B1, Anti-Hydroperoxy icosatetraenoate dehydratase, CYP1B1 Antibody |
| Anwendung: | WB, IHC (paraffin), FC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-CYP1B1
Artikelnummer: NSJ-F50866-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. CYP1B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme localizes to the endoplasmic...
| Schlagworte: | Anti-CYP1B1, Anti-CYPIB1, Anti-Cytochrome P450 1B1, CYP1B1 Antibody |
| Anwendung: | WB, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 361,00 €
Anti-CYP1B1
Artikelnummer: ARG57798.100
Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes...
| Schlagworte: | Anti-CYPIB1, Anti-CYP1B1, Anti-Cytochrome P450 1B1 |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Alizarin
Artikelnummer: Cay11676-50
Alizarin is a small molecule inhibitor of cytochrome P450 isoforms CYP1A1, CYP1A2, and CYP1B1 (IC50s = 6.2, 10, and 2.7 µM, respectively). Alizarin acts as an antioxidant against iodophenol-derived phenoxyl radicals, superoxide anion radicals, and lipid peroxidation in rat liver microsomes. It also reduces hepatic...
| Schlagworte: | CI-58000, NSC 7212, 1,2-dihydroxy-9,10-anthracenedione |
| Anwendung: | CYP1A1 / CYP1A2 / CYP1B1 inhibitor |
| CAS | 72-48-0 |
| MW: | 240.2 D |
ab 49,00 €
Anti-CYP1B1
Artikelnummer: ARG57799.50
Protein function: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, retinoid and xenobiotics. Preferentially oxidizes...
| Schlagworte: | Anti-CYP1B1, Anti-CYPIB1, Anti-Cytochrome P450 1B1 |
| Anwendung: | IHC (paraffin), WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
559,00 €
TMS
Artikelnummer: LKT-T503720.100
| Schlagworte: | 2,3',4,5'-Tetramethoxystilbene, 2,4,3',5'-tetramethoxystilbene, 3,5,2',4'-tetramethoxy-trans-stilbene, AC1NS4S6,... |
| Anwendung: | CYP1B1 inhibitor |
| CAS | 24144-92-1 |
| MW: | 300.35 D |
ab 67,00 €