Zu "K07375" wurden 491 Artikel gefunden!
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Nocodazole
Artikelnummer: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Schlagworte: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Anwendung: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
ab 54,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
Anti-Recombinant beta II Tubulin, clone A592
Artikelnummer: E-AN301880L.100
Beta-tubulin is a protein that forms the backbone of cells. Tubulin can be divided into several kinds of Tubulin, including alpha, beta, gamma, delta, and epsilon, among which alpha -tubulin and beta -tubulin can form heterodimers and are the two most important Tubulin for microtubule formation. The molecular...
| Schlagworte: | Anti-TUBB2B, Anti-Tubulin beta-2B chain, Recombinant beta II Tubulin Monoclonal Antibody |
| Anwendung: | WB, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-Recombinant beta III Tubulin, clone A651
Artikelnummer: E-AN301935L.100
Beta III Tubulin (TUBB3) is one of six beta-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation). Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS). Microtubules enriched in...
| Schlagworte: | Anti-TUBB3, Anti-Tubulin beta-III, Anti-Tubulin beta-4 chain, Anti-Tubulin beta-3 chain, Recombinant beta III Tubulin... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Anti-Recombinant beta IV Tubulin, clone A657
Artikelnummer: E-AN301941L.100
Beta IV Tubulin (TUBB4) is a member of the beta tubulin family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in TUBB4 cause hypomyelinating leukodystrophy and autosomal dominant torsion dystonia. Alternate splicing of...
| Schlagworte: | Anti-TUBB4A, Anti-Tubulin 5 beta, Anti-Tubulin beta-4 chain, Anti-Tubulin beta-4A chain, Recombinant beta IV Tubulin... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, rat, mouse |
ab 304,00 €
Paclitaxel
Artikelnummer: Cay10461-25
Paclitaxel, a potent disruptor of microtubules derived from the bark of the Pacific yew tree, is widely used as a chemotherapeutic compound. Tested against a panel of cervical (HeLa), lung (A549), breast (MCF-7), colon (HT-29), ovarian (OVG-1), and pancreatic (PC-Sh) carcinomas, paclitaxel demonstrates IC50 values...
| Schlagworte: | NSC 125973, betaS-(benzoylamino)-alphaR-hydroxy-benzenepropanoic acid,... |
| Anwendung: | Apotosis inducer |
| CAS | 33069-62-4 |
| MW: | 853.9 D |
ab 53,00 €
Anti-Tubulin (glycylated) (Gly-pep1)
Artikelnummer: AG-25B-0034-C100
Polyclonal Antibody. This antibody recognizes mono or bi-glycylated Tubulins. The activity of glycylating enzymes (TTLL3 and TTLL8) in cultured cells leads mainly to the modification of alpha- and beta-tubulin, but also of other, yet unidentified protein substrates also detected by the antibody Gly-pep1. In...
| Schlagworte: | Anti-TUBB2, Anti-TUBB2A, Anti-Tubulin beta-2A chain, Anti-Tubulin beta class IIa |
| Anwendung: | ICC, IP, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | dog, human, mouse |
418,00 €
Vinblastine (sulfate)
Artikelnummer: Cay11762-10
Vinblastine, derived from C. roseus, also known as V. rosea, a Madagascar periwinkle, is an antimicrotubule drug used to treat certain cancers, including Hodgkin's lymphoma, non-small cell lung, breast, head and neck, and testicular cancer. Like its chemical analog vincristine, vinblastine binds tubulin, inhibiting...
| Schlagworte: | 29060LE, Alkaban-AQ, Exal, NSC 49842, Rozevinsulfate, Velban(R), Velsar, Vincaleukoblastinesulfate, VLB,... |
| Anwendung: | Vincristine analog, Cancer studies |
| CAS | 143-67-9 |
| MW: | 909.1 D |
ab 85,00 €
Vincristine . sulfate
Artikelnummer: AG-CN2-0446-M005
White to light-yellow powder. Soluble in water, DMSO or methanol. Immunosuppressant, Anticancer compound. Chemotherapeutic agent, Depolymerizes microtubules and irreversibly blocks binding of tubulin to microtubule proteins, Apoptosis inducer and cell cycle inhibitor in G2/M phase, Autophagy inhibitor. Inhibits...
| Schlagworte: | VCR, 22-Oxovincaleukoblastine, NSC 67574, Oncovin, Lilly 37231, Leucristine, Leurocristine, LS-228 |
| Anwendung: | Tubulin polymerization inhibitor |
| CAS | 2068-78-2 |
| MW: | 923,1 D |
ab 50,00 €
Anti-beta-Tubulin (beta-monoE), pAb (IN115)
Artikelnummer: AG-25B-0039-C050
Polyglutamylation is an evolutionarily conserved protein post-translational modification in which glutamate side chains of variable lengths are formed on the modified protein. The most prominent substrate is tubulin, the building block of microtubules (MTs). Polyglutamylation has been found on both, alpha- and...
| Schlagworte: | Anti-TUBB2, Anti-TUBB2A, Anti-Tubulin beta-2A chain, Anti-Tubulin beta class IIa |
| Anwendung: | WB, ICC, IHC, IP |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
429,00 €
Nocodazole
Artikelnummer: AG-CR1-0019-M050
Microtubule inhibitor, Antitumor compound, Mitosis inhibitor, Arrests the cell cycle at G2/M phase, Promotes tubulin depolymerization, Induces fragmentation of the Golgi complex, Inhibits the T cell antigen receptor, Stimulates the intrinsic GTPase activity of tubulin, Activates the JNK/SAPK signaling pathway,...
| Schlagworte: | Methyl[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]carbamate |
| Anwendung: | Microtubule inhibitor, Mitosis inhibitor |
| CAS | 31430-18-9 |
| MW: | 301,3 D |
ab 39,00 €
Mebendazole
Artikelnummer: Cay18872-10
Mebendazole is an inhibitor of microtubule polymerization and an anthelmintic. It reduces microtubule polymerization in a cell-free assay when used at a concentration of 10 µM. Mebendazole reduces container attachment, a measure of viability, by G. duodenalis with a half-maximal inhibition of binding (IB50) value of...
| Schlagworte: | NSC 184849, R 17635, N-(6-benzoyl-1H-benzimidazol-2-yl)-carbamic acid, methyl ester |
| Anwendung: | Anthelmintic, microtubule synthesis inhibitor |
| CAS | 31431-39-7 |
| MW: | 295.3 D |
ab 49,00 €