Zu "K07375" wurden 273 Artikel gefunden!
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Nocodazole
Artikelnummer: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Schlagworte: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Anwendung: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
ab 48,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
Anti-Beta Tubulin, clone 2E11.
Artikelnummer: NSJ-RQ5619
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Tubulin beta chain is a protein that in humans is encoded by the TUBB gene. This gene encodes a beta tubulin protein. This protein forms a dimer with alpha tubulin and acts as a structural component of microtubules. Mutations in this gene cause cortical...
| Schlagworte: | Anti-TUBB, Anti-TUBB5, Anti-Tubulin beta chain, Anti-Tubulin beta-5 chain, Beta Tubulin Antibody |
| Anwendung: | WB, FC, ICC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat |
755,00 €
SSE1806
Artikelnummer: Cay39780-1
SSE1806 is a microtubule destabilizer. It inhibits tubulin polymerization in a cell-free assay when used at a concentration of 10 µM. SSE1806 inhibits the growth of MCF-7 breast cancer, HCT116 colon cancer, K562 leukemia, and KB-3-1 and paclitaxel-resistant KB-V1 cervical cancer cells (GI50s = 5.02, 2.01, 17.74,...
| Schlagworte: | 11-(3-nitrophenyl)-2,3,7,8,9,11-hexahydro-[1,4]dioxino[2,3-b]acridin-10(6H)-one |
| Anwendung: | Microtubule destabilizer |
| MW: | 378.4 D |
ab 35,00 €
Human TUBb1 (Tubulin Beta 1) ELISA Kit
Artikelnummer: ELK-ELK5509.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb1. Next,...
| Schlagworte: | TUBB1, Tubulin beta-1 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Mouse TUBb1 (Tubulin Beta 1) ELISA Kit
Artikelnummer: ELK-ELK6324.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TUBb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TUBb1. Next,...
| Schlagworte: | Tubb1, Tubulin beta-1 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 365,00 €
Human TUBb3 (Tubulin Beta 3) ELISA Kit
Artikelnummer: ELK-ELK4113.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb3. Next,...
| Schlagworte: | TUBB4, TUBB3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 365,00 €
Human TUBb (Tubulin Beta) ELISA Kit
Artikelnummer: ELK-ELK5140.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb. Next,...
| Schlagworte: | TUBB, TUBB5, Tubulin beta chain, Tubulin beta-5 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 303,00 €
Anti-beta II Tubulin
Artikelnummer: ELK-EA048.50
Tubulin is the major constituent of microtubules. It exists as a heterodimer consiting of an alpha and a beta subunit. Class II beta tubulin is the major form of tubulin beta in neurons, although it is not neuronal specific. It is found in many other tissues including lung tissue and Schwann cells. Protein function:...
| Schlagworte: | Anti-TUBB2C, Anti-TUBB4B, Anti-Tubulin beta-2 chain, Anti-Tubulin beta-4B chain, Anti-Tubulin beta-2C chain, beta II... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
169,00 €
Anti-beta III Tubulin
Artikelnummer: ELK-EA049.100
Tubulin is the major constituent of microtubules. It exists as a heterodimer consiting of an alpha and a beta subunit. TUBB3 plays a critical role in proper axon guidance and mantainance. Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear...
| Schlagworte: | Anti-TUBB4, Anti-TUBB3, Anti-Tubulin beta-III, Anti-Tubulin beta-4 chain, Anti-Tubulin beta-3 chain, beta III Tubulin... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
Anti-beta Tubulin
Artikelnummer: ELK-EA058.100
Microtubules are constituent parts of the mitotic apparatus, cilia, flagella, and elements of the cytoskeleton. They consist principally of 2 soluble proteins, alpha- and beta-tubulin, each of about 55,000 Da. Antibodies against beta Tubulin are useful as loading controls for Western Blotting. However it should be...
| Schlagworte: | Anti-TUBB, Anti-TUBB5, Anti-Tubulin beta chain, Anti-Tubulin beta-5 chain, beta Tubulin Rabbit pAb |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €
S-72
Artikelnummer: Cay39083-10
S-72 is an inhibitor of microtubule polymerization. It inhibits microtubule polymerization in a cell-free assay when used at concentrations 1, 3, and 10 µM. S-72 reduces viability in MCF-7 and paclitaxel-resistant MCF-7/T breast cancer cells (IC50s = 15.64 and 26.32 nM, respectively). It inhibits migration and...
| Schlagworte: | 4-methyl-3-[[(4-methylphenyl)sulfonyl]amino]-N-[(1-methyl-1H-pyrazol-4-yl)methyl]-benzamide |
| Anwendung: | Microtubule polymerization inhibitor |
| CAS | 2446799-14-8 |
| MW: | 398.5 D |
ab 82,00 €