Zu "K07375" wurden 521 Artikel gefunden!
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Nocodazole
Artikelnummer: Cay13857-5
Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...
| Schlagworte: | NSC 238159, Oncodazole, R 17934, N-[6-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamic acid, methyl ester |
| Anwendung: | Microtubule function studies, cell cycle arrest |
| CAS | 31430-18-9 |
| MW: | 301.3 D |
ab 57,00 €
NEU
Auristatin PE
Artikelnummer: Cay45983-1
Auristatin PE is a tubulin polymerization inhibitor, an anticancer agent, and a derivative of dolastatin 10. It inhibits tubulin polymerization (IC50< = 2.2 µM), completely inhibits the proliferation of WSU-WM Waldenström's macroglobulinemia cells at 100 pg/ml, and induces cell cycle arrest at the G2/M phase and...
| Schlagworte: | NSC 654663, Soblidotin, TZT-1027, YHI-501,... |
| Anwendung: | Tubulin polymerization inhibitor |
| CAS | 149606-27-9 |
| MW: | 701.99 D |
ab 194,00 €
NEU
Anti-Recombinant TBB4A, clone C112608
Artikelnummer: E-AN302988L.100
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap,...
| Schlagworte: | Anti-TUBB4A, Anti-Tubulin 5 beta, Anti-Tubulin beta-4 chain, Anti-Tubulin beta-4A chain, Recombinant TBB4A Monoclonal... |
| Anwendung: | WB, IHC, IF, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant beta IV Tubulin, clone C112679
Artikelnummer: E-AN303059L.100
Protein function: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap,...
| Schlagworte: | Anti-TUBB4A, Anti-Tubulin 5 beta, Anti-Tubulin beta-4 chain, Anti-Tubulin beta-4A chain, Recombinant beta IV Tubulin... |
| Anwendung: | WB, IHC, ICC/IF, FCM |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Paclitaxel
Artikelnummer: AG-CN2-0045-M005
Anticancer compound. Chemotherapeutic used in patients with cancer and advanced forms of Kaposi's sarcoma. Microtubule assembly stabilizer. Reversibly binds to polymerized tubulin. Anti-mitotic. Mitotic spindle assembly, chromosome segregation and cell division inhibitor. Induces cell cycle arrest at the G2/M phase....
| Schlagworte: | Taxol, BMS 181339-01, NSC 125973 |
| Anwendung: | Apoptosis Inducer |
| Wirt: | Taxus brevifolia |
| CAS | 33069-62-4 |
| MW: | 853,9 D |
ab 22,00 €
RGN6024
Artikelnummer: Cay45752-1
RGN6024 is a tubulin destabilizer. It reduces tumor growth in a temozolomide-resistant LN-18 glioblastoma mouse xenograft model when administered orally at doses of 7.5 or 15 mg/kg.. SMILES: O=C(C12CC(C1)(C2)OC)NC3=NC=C(S3)OC(C=N4)=CN=C4N5CCOCC5. InChi Code:...
| Schlagworte: | 3-methoxy-N-[5-[[2-(4-morpholinyl)-5-pyrimidinyl]oxy]-2-thiazolyl]-bicyclo[1.1.1]pentane-1-carboxamide |
| Anwendung: | Tubulin destabilizer |
| CAS | 3055038-20-2 |
| MW: | 403.46 D |
ab 69,00 €
Mertansine
Artikelnummer: BPS-84307-1
Mertansine, also known as DM1, is a microtubule inhibitor and is an antibody-conjugatable maytansinoid that was developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug...
| Anwendung: | ADC (antibody drug conjugate) preparation |
| CAS | 139504-50-0 |
| MW: | 738.29 D |
ab 400,00 €
Human TUBb1 (Tubulin Beta 1) Microsample ELISA Kit
Artikelnummer: ELK-ELK5509MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb1. Next,...
| Schlagworte: | TUBB1, Tubulin beta-1 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Mouse TUBb1 (Tubulin Beta 1) Microsample ELISA Kit
Artikelnummer: ELK-ELK6324MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TUBb1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TUBb1. Next,...
| Schlagworte: | Tubb1, Tubulin beta-1 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 374,00 €
Human TUBb3 (Tubulin Beta 3) Microsample ELISA Kit
Artikelnummer: ELK-ELK4113MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb3. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb3. Next,...
| Schlagworte: | TUBB3, Tubulin beta-III, Tubulin beta-3 chain, Tubulin beta-4 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 374,00 €
Human TUBb (Tubulin Beta) Microsample ELISA Kit
Artikelnummer: ELK-ELK5140MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human TUBb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human TUBb. Next,...
| Schlagworte: | TUBB, Tubulin beta chain, Tubulin beta-5 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
ab 311,00 €
Mouse TUBb (Tubulin Beta) Microsample ELISA Kit
Artikelnummer: ELK-ELK9799MS.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Mouse TUBb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Mouse TUBb. Next,...
| Schlagworte: | Tubb5, Tubulin beta-5 chain |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
ab 311,00 €