Zu "K07209" wurden 125 Artikel gefunden!
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NEU
Anti-Recombinant IKK beta, clone C171785
Artikelnummer: E-AN302165L.100
Protein function: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses (PubMed:20434986, PubMed:20797629, PubMed:21138416, PubMed:30337470,...
| Schlagworte: | Anti-IKBKB, Anti-I-kappa-B kinase 2, Anti-Serine/threonine protein kinase IKBKB, Anti-Nuclear factor NF-kappa-B inhibitor... |
| Anwendung: | WB, IF, IP, ELISA |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
NEU
Anti-Recombinant IKK beta, clone C122854
Artikelnummer: E-AN303234L.100
Protein function: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses (PubMed:20434986, PubMed:20797629, PubMed:21138416, PubMed:30337470,...
| Schlagworte: | Anti-IKBKB, Anti-I-kappa-B kinase 2, Anti-Serine/threonine protein kinase IKBKB, Anti-Nuclear factor NF-kappa-B inhibitor... |
| Anwendung: | WB, IHC |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human,mouse,rat |
ab 171,00 €
Rat IkBKb (Inhibitor Of Kappa-Light Polypeptide Gene...
Artikelnummer: ELK-ELK10064.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat IkBKb. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat IkBKb. Next,...
| Schlagworte: | Ikbkb, I-kappa-B kinase 2, Serine/threonine protein kinase IKBKB, Nuclear factor NF-kappa-B inhibitor kinase beta,... |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | rat |
ab 374,00 €
IKBKB Protein, Human, Recombinant (His)
Artikelnummer: TGM-TMPH-01531-10ug
Description: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B...
| Schlagworte: | Serine/threonine protein kinase IKBKB , IkBKB , IKBKB , I-kappa-B kinase 2 (IKK-2,IKK2) , IKK-beta , I-kappa-B-kinase beta... |
| MW: | 89.1 kD |
ab 166,00 €
BMS 345541 (hydrochloride)
Artikelnummer: Cay16667-1
BMS 345541 is a cell permeable inhibitor of the IkappaB kinases IKKalpha and IKKbeta (IC50s = 4 and 0.3 µM). It is without effect against a panel of other serine/threonine and tyrosine kinases at 100 µM. BMS 345541 inhibits signaling through nuclear factor-kappaB (NF-kappaB) both in cells and in vivo, showing...
| Schlagworte: | IKK Inhibitor III, N1-(1,8-dimethylimidazo[1,2-a]quinoxalin-4-yl)-1,2-ethanediamine, bis(2,2,2-trifluoroacetate) |
| Anwendung: | Cell permeable IKK-alpha/beta inhibitor |
| CAS | 547757-23-3 |
| MW: | 291.8 D |
ab 69,00 €
COVID-19 Forschung
Auranofin
Artikelnummer: AG-CR1-3611-M025
White to off-white solid. Soluble in DMSO or 100% ethanol. Insoluble in water. Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway, Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5, Potent thioredoxin...
| Schlagworte: | 1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate, NSC 321521, SKF 39162 |
| Anwendung: | Antiinflammatory agent |
| CAS | 34031-32-8 |
| MW: | 678,5 D |
ab 66,00 €
IKK-16 (hydrochloride)
Artikelnummer: Cay13313-5
IKK-16 is a potent inhibitor of IkappaB kinases (IKKs), displaying IC50 values of 200, 40, and 70 nM for IKKalpha, IKKbeta, and IKK complex, respectively, in cell-free assays. It is effective in cells and in animals and has been used delineate the role of NF-kappaB signaling in diverse contexts. IKK-16 has also been...
| Schlagworte: | IKK Inhibitor VII, [4-[(4-benzo[b]thien-2-yl-2-pyrimidinyl)amino]phenyl][4-(1-pyrrolidinyl)-1-piperidinyl]-methanone,... |
| Anwendung: | IkappaB kinase inhibitor |
| CAS | 1186195-62-9 |
| MW: | 520.1 D |
ab 144,00 €
BI-605906
Artikelnummer: Cay19184-1
BI-605906 is an inhibitor of inhibitor of kappa B kinase subunit beta (IKKbeta, IC50 = 380 nM). It is selective for IKKbeta over insulin-like growth factor 1 (IGF1, IC50 = 7.6 µM) and over 100 kinases in a panel up to 10 µM. BI-605906 partially inhibits IL-1-stimulated activation of IKKepsilon/TBK1 in vitro....
| Schlagworte: | 3-amino-4-(1,1-difluoropropyl)-6-[4-(methylsulfonyl)-1-piperidinyl]-thieno[2,3-b]pyridine-2-carboxamide |
| Anwendung: | IKK beta inhibitor |
| CAS | 960293-88-3 |
| MW: | 432.5 D |
ab 118,00 €
SC-514
Artikelnummer: TGM-T2118-5mg
Description: SC-514 (GK 01140) is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 µM), obstructs NF-kappaB-dependent gene expression. Target: IkappaB/IKK, p38 MAPK, CDK, Aurora Kinase, Serine Protease. Smiles: NC(=O)c1sc(cc1N)-c1ccsc1. References: Kishore N, et al. J Biol Chem, 2003,...
| Schlagworte: | GK 01140 |
| Anwendung: | IKK2 inhibitor |
| CAS | 354812-17-2 |
| MW: | 224.3 D |
ab 30,00 €
SC-514
Artikelnummer: Cay10010267-10
SC-514 is a selective and reversible inhibitor of IkappaB kinase 2 (IKK2) (IC50 = 3-12 µM) that displays greater than 10-fold selectivity over 28 other kinases, including JNK, p38, MK2, and ERK. In synovial fibroblasts stimulated with interleukin (IL)-1beta, SC-514 attenuates NF-kappaB-mediated expression of IL-6,...
| Schlagworte: | 4-amino-[2,3'-bithiophene]-5-carboxamide |
| Anwendung: | IKK2 inhibitor |
| CAS | 354812-17-2 |
| MW: | 224.3 D |
ab 54,00 €
Anti-IKKbeta, clone 10AG2
Artikelnummer: 200-301-H83
Anti-IKKbeta Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with IKKbeta from Human and Mouse based on 100% homology with the immunizing sequence. Cross-reactivity withAnti-IKKbeta from other sources has not been determined. Protein function: Serine kinase...
| Schlagworte: | Anti-IKK2, Anti-IKKB, Anti-IKBKB, Anti-IKK-B, Anti-IkBKB, Anti-NFKBIKB, Anti-IKK-beta, EC=2.7.11.10, Anti-I-kappa-B kinase... |
| Anwendung: | FC, IHC, IP, WB |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse |
819,00 €
PS-1145
Artikelnummer: Cay14862-1
PS-1145 is an IkappaB kinase beta (IKKbeta) inhibitor (IC50 = 88 nM). It selectively inhibits IKKbeta over a panel of 14 kinases (IC50s = >100 nM for all). PS-1145 also inhibits the IKK complex (IC50 = 100 nM). It inhibits the proliferation of MM.1S, U266, and RPMI-8226 myeloma cells when used at concentrations...
| Schlagworte: | IKK Inhibitor X, N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)-3-pyridinecarboxamide |
| Anwendung: | IKKbeta inhibitor |
| CAS | 431898-65-6 |
| MW: | 322.8 D |
ab 51,00 €