Zu "K07199" wurden 88 Artikel gefunden!
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Dorsomorphin
Artikelnummer: Cay11967-5
Dorsomorphin is a potent, reversible inhibitor of AMPK (Ki = 109 nM) that does not exhibit significant activity on structurally related kinases, including ZAPK, SYK, PKCtheta, PKA, and JAK3. Dorsomorphin can also dose-dependently inhibit the bone morphogenetic protein type 1 receptors ACTR-I (ALK2), BMPR-IA (ALK3),...
| Schlagworte: | BML-275, Compound C, 6-[4-[2-(1-piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine |
| Anwendung: | AMPK inhibitor, autophagy inducer |
| CAS | 866405-64-3 |
| MW: | 399.5 D |
ab 85,00 €
AMPK activator
Artikelnummer: Cay14741-10
AMPK activator is an indirect activator of AMP-activated protein kinase, AMPK (EC50 = 11.7 µM). It is thought to activate AMPK by inhibiting mitochondrial complex I, producing an increase in AMP levels. AMPK activator stimulates glucose uptake in L6 myocytes and promotes phosphorylation of acetyl-CoA carboxylase, a...
| Schlagworte: | D942, 5-[3-[4-[2-(4-fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic acid |
| Anwendung: | AMPK activator |
| CAS | 849727-81-7 |
| MW: | 368.4 D |
ab 85,00 €
PF-06409577
Artikelnummer: Cay27366-1
PF-06409577 is an activator of AMP-activated protein kinase (AMPK) heterotrimers (Kd = 9 nM for alpha1beta1gamma1). In vitro, it selectively activates beta1-containing AMPK isoforms (EC50s = 2.18-7.03 nM) over beta2-containing isoforms (EC50s = >10 µM). PF-06409577 has an EC50 value of 7 nM in an...
| Schlagworte: | 6-chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic acid |
| Anwendung: | AMPK heterotrimer activator |
| CAS | 1467057-23-3 |
| MW: | 341.8 D |
ab 49,00 €
Anti-AMPK alpha 1 / AMPK alpha 2phospho (Thr183/Thr172)
Artikelnummer: ARG51678.100
Protein function: Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits...
| Schlagworte: | Anti-phospho-AMPK1, Anti-phospho-PRKAA1, Anti-phospho-ACACA kinase, EC=2.7.11.26, Anti-phospho-HMGCR kinase,... |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
ab 460,00 €
Anti-AMPK beta 1, clone 1A7-E11-E9
Artikelnummer: ARG54128.100
Protein function: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes:...
| Schlagworte: | Anti-AMPK, Anti-AMPKb, Anti-PRKAB1, Anti-AMPK subunit beta-1, Anti-5'-AMP-activated protein kinase subunit beta-1 |
| Anwendung: | WB, ICC, IF, IP, IHC (paraffin) |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human, mouse, rat, monkey |
658,00 €
Anti-AMPK beta 2
Artikelnummer: ARG56343.100
Protein function: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes:...
| Schlagworte: | Anti-PRKAB2, Anti-AMPK subunit beta-2, Anti-5'-AMP-activated protein kinase subunit beta-2 |
| Anwendung: | WB, IHC (paraffin), ICC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Anti-AMPK beta 1
Artikelnummer: ARG56387.100
Protein function: Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes:...
| Schlagworte: | Anti-AMPK, Anti-AMPKb, Anti-PRKAB1, Anti-AMPK subunit beta-1, Anti-5'-AMP-activated protein kinase subunit beta-1 |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
707,00 €
Human PRKAB1 / 5'-AMP-activated kinase subunit beta-1...
Artikelnummer: G-HUFI01573.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Human pAMPK / Phosphorylated Adenosine Monophosphate...
Artikelnummer: G-HUFI02202.96
| Anwendung: | ELISA |
| Spezies-Reaktivität: | human |
698,00 €
Anti-AMPK beta 2 / PRKAB2
Artikelnummer: NSJ-R31820
0.5mg/ml if reconstituted with 0.2ml sterile DI water. 5'-AMP-activated protein kinase subunit beta-2 is an enzyme that in humans is encoded by the PRKAB2 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic...
| Schlagworte: | Anti-PRKAB2, Anti-AMPK subunit beta-2, Anti-5'-AMP-activated protein kinase subunit beta-2, AMPK beta 2 Antibody / PRKAB2 |
| Anwendung: | WB, IHC (paraffin) |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse, rat |
790,00 €
Anti-AMPK beta 1 / PRKAB1
Artikelnummer: NSJ-R32363
0.5mg/ml if reconstituted with 0.2ml sterile DI water. 5'-AMP-activated protein kinase subunit beta-1 is an enzyme that in humans is encoded by the PRKAB1 gene. The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic...
| Schlagworte: | Anti-AMPK, Anti-AMPKb, Anti-PRKAB1, Anti-AMPK subunit beta-1, Anti-5'-AMP-activated protein kinase subunit beta-1, AMPK... |
| Anwendung: | WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
790,00 €
ZLN024
Artikelnummer: Cay21644-25
ZLN024 is an allosteric activator of AMP-activated protein kinase (AMPK) heterotrimers (EC50s = 0.42 and 0.95 µM for alpha1beta1gamma1 and alpha2beta1gamma1, respectively). Activation of AMPK by ZLN024 requires phosphorylation of AMPK on Thr172, and ZLN024 protects Thr172 from dephosphorylation by protein...
| Schlagworte: | 2-[[2-(2-bromo-4-methylphenoxy)ethyl]thio]-pyrimidine |
| Anwendung: | AMPK activator |
| CAS | 723249-01-2 |
| MW: | 325.2 D |
ab 143,00 €