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Zu "K06744" wurden 853 Artikel gefunden!
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NEU
Artikelnummer: BPS-83965-1
Nivolumab, also known as BMS-936558, is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody. This antibody is used in the treatment of several cancer types, from melanoma to Hodgkin lymphoma. PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 946414-94-4 |
ab 774,00 €
Artikelnummer: E-AN301420L.100
The programmed cell death 1 protein (PD1) is an inhibitory receptor expressed on antigen activated T-cells that plays a critical role in the induction and maintenance of immune tolerance to self-antigens. Upon binding to its ligands CD274/PDCD1L1 (PD-L1) and CD273/PDCD1LG2 (PD-L2), PD1 is phosphorylated within its...
| Schlagworte: | Anti-PDCD1, Anti-Programmed cell death protein 1, Recombinant PD1 Monoclonal Antibody |
| Anwendung: | IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
ab 304,00 €
Artikelnummer: Cay45002-500
Programmed cell death protein 1 (PD-1), also known as CD279, is a cell surface receptor belonging to the immunoglobulin superfamily that is involved in regulation and attenuation of the adaptive immune response. It is a 288-amino acid type I transmembrane protein encoded by the PDCD1 gene in humans and is composed...
| Schlagworte: | CD279, PDCD1, Programmed Cell Death Protein 1 |
| Anwendung: | FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
213,00 €
Artikelnummer: BPS-83879-1
Pembrolizumab, also known as MK-3475, is a humanized IgG4 antibody able to inhibit the PD-1 (programmed cell death 1). PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells that binds to PD-L1 or PD-L2, inducing apoptosis of T cells and inhibiting immune...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Anwendung: | ELISA, FC, FA |
| Wirt: | Human |
| Spezies-Reaktivität: | human |
| CAS | 1374853-91-4 |
ab 720,00 €
Artikelnummer: ARG81342.96
Protein function: Inhibitory cell surface receptor involved in the regulation of T-cell function during immunity and tolerance. Upon ligand binding, inhibits T-cell effector functions in an antigen- specific manner. Possible cell death inducer, in association with other factors. [The UniProt Consortium]
| Schlagworte: | Pd1, Pdcd1, CD279, mPD-1, Protein PD-1, Programmed cell death protein 1 |
| Anwendung: | ELISA |
| Spezies-Reaktivität: | mouse |
734,00 €
Artikelnummer: GSC-Z03370-1
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds two ligands, PD-L1...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Ursprungsart: | human |
ab 161,00 €
Artikelnummer: GSC-Z03383-1
Programmed cell death protein 1, also known as PD-1 and CD279 (cluster of differentiation 279) or PDCD1, is a protein that in humans is encoded by the PDCD1 gene. PD-1 is a cell surface receptor that belongs to the immunoglobulin superfamily and is expressed on T cells and pro-B cells.PD-1 binds two ligands, PD-L1...
| Schlagworte: | Pdcd1, Programmed cell death protein 1 |
| Ursprungsart: | mouse |
ab 161,00 €
Artikelnummer: GSC-Z03424-1
Programmed death (PD-1) is an immunoinhibitory receptor that belongs to the CD28 family and is expressed on T cells, B cells, monocytes, natural killer cells, and many tumor-infiltrating lymphocytes (TILs), PD-1 is a type I membrane protein of 268 amino acids and which structure includes an extracellular IgV domain...
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
| Ursprungsart: | human |
ab 269,00 €
Artikelnummer: GSC-M00630
Recombinant Daudi cells stably overexpress human programmed cell death protein 1 (PD-1) on the surface. The surface expression of PD-1 is validated by FACS analysis.
| Schlagworte: | PDCD1, Programmed cell death protein 1 |
11.424,00 €
Artikelnummer: GSC-A01829-40
The product is specific for human PD-1 (UniProt Accession: Q15116). This antibody blocks human PD-L1 binding with human PD-1 expression cell line in flow cytometry assay.
| Schlagworte: | Anti-PDCD1, Anti-Programmed cell death protein 1 |
| Anwendung: | ELISA, FC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
152,00 €
Artikelnummer: GSC-V02201-0.1
Programmed Cell Death Protein 1 (PD-1), is cell surface receptor expressing on T cells and pro-B cells. The binding of PD-1 to its two ligands, PD-L1 and PD-L2, could result in down-regulation of the immune system by inhibiting the T-cell activation process. Thus, PD-1 is an important immune checkpoint and a popular...
| Schlagworte: | Anti-PDCD1, Anti-Programmed cell death protein 1 |
| Anwendung: | IHC |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 407,00 €
Artikelnummer: GSC-Z04675-100
Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
| Schlagworte: | Pdcd1, Programmed cell death protein 1 |
| Ursprungsart: | mouse |
| MW: | 42.9 kD |
ab 887,00 €