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Zu "K06744" wurden 585 Artikel gefunden!
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Artikelnummer: NAV-PPI.PDL1.FR.100
The Naveni PD1/PD-L1 is an in situ proximity ligation assay kit for the detection of the interaction of PD1 and PD-L1. This in situ kit gives a high signal-to-noise ratio and has an out-standing specificity. The kit is comatible with immunofluorescence co-staining for visualization of the tumor microenvironment. The...
Schlagworte: | NAV-NPT.PDL1.Atto647N.100, Anti-hPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | PLA |
2.850,00 €
Artikelnummer: Cay39663-1
PD-1/PD-L1 inhibitor N11 is an inhibitor of the protein-protein interaction between programmed cell death protein 1 (PD-1) and PD-1 ligand (PD-L1, IC50 = 6.3 nM). It increases T cell proliferation in a PD-L1-overexpressing CT26 colon cancer cell and T cell co-culture when used at a concentration of 20 nM. PD-1/PD-L1...
Schlagworte: | PD-1/PD-L1 Interaction Inhibitor, Programmed Cell Death 1/Programmed Cell Death-Ligand 1 Inhibitor N11,... |
Anwendung: | PD-1/PD-L1 interaction inhibitor |
MW: | 425.5 D |
ab 155,00 €
Artikelnummer: ELK-ELK4353.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human PDCD1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human PDCD1. Next,...
Schlagworte: | CD279, hPD-1, Protein PD-1, Programmed cell death protein 1 |
Anwendung: | ELISA |
Spezies-Reaktivität: | human |
ab 365,00 €
Artikelnummer: Cay38781-1
INCB 086550 is an inhibitor of the protein-protein interaction between programmed cell death 1 (PD-1) and its ligand PD-L1. It inhibits PD-1 binding to PD-L1 in CHO cells expressing human PD-L1 (EC50 = 13.2 nM). INCB 086550 (1 µM) induces dimerization and internalization of PD-L1 in CHO cells expressing human PD-L1....
Schlagworte: | (3R)-1-[[7-cyano-2-[3'-[[3-[[(3R)-3-hydroxy-1-pyrrolidinyl]methyl]-1,7-naphthyridin-8-yl]amino]-2,2'-dimethyl[1,1'-bipheny... |
Anwendung: | PD-1/PD-L1 interaction inhibitor |
CAS | 2230911-59-6 |
MW: | 693.8 D |
ab 77,00 €
Artikelnummer: G-IVMB0209.1
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2...
Schlagworte: | Anti-hPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | WB, FA, FC, IHC |
Wirt: | Human |
Spezies-Reaktivität: | human, Cynomolgus monkey |
ab 266,00 €
Artikelnummer: G-IVMB0210.500
Endotoxin level: < 1.0 EU/mg as determined by the LAL method. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:21276005). Delivers inhibitory signals upon binding to ligands CD274/PDCD1L1 and CD273/PDCD1LG2...
Schlagworte: | Anti-hPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | WB, FA, FC, IHC |
Wirt: | Human |
Spezies-Reaktivität: | human, Cynomolgus monkey |
620,00 €
Artikelnummer: G-IVMB0279.1
Endotoxin level: <1.0 EU/µg. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:10485649, PubMed:11698646, PubMed:11209085, PubMed:21300912). Delivers inhibitory signals upon binding to ligands, such as...
Schlagworte: | Anti-CD279, Anti-mPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | WB, FA, in vivo, WB |
Wirt: | Mouse/Rat |
Spezies-Reaktivität: | mouse |
ab 277,00 €
Artikelnummer: G-IVMB0280.1
Endotoxin level: <1.0 EU/µg. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:10485649, PubMed:11698646, PubMed:11209085, PubMed:21300912). Delivers inhibitory signals upon binding to ligands, such as...
Schlagworte: | Anti-CD279, Anti-mPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | WB, FA, in vivo, WB |
Wirt: | Mouse/Rat |
Spezies-Reaktivität: | mouse |
ab 277,00 €
Artikelnummer: G-IVMB0281.1
Endotoxin level: <1.0 EU/µg. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:10485649, PubMed:11698646, PubMed:11209085, PubMed:21300912). Delivers inhibitory signals upon binding to ligands, such as...
Schlagworte: | Anti-CD279, Anti-mPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | WB, FA, IHC, in vivo, WB |
Wirt: | Mouse/Rat |
Spezies-Reaktivität: | mouse |
ab 224,00 €
Artikelnummer: G-IVMB0338.500
Endotoxin level: <1.0 EU/µg as determined by the LAL method. Protein function: Inhibitory receptor on antigen activated T-cells that plays a critical role in induction and maintenance of immune tolerance to self (PubMed:10485649, PubMed:11698646, PubMed:11209085, PubMed:21300912). Delivers inhibitory signals upon...
Schlagworte: | Anti-CD279, Anti-mPD-1, Anti-Protein PD-1, Anti-Programmed cell death protein 1 |
Anwendung: | FC, in vivo |
Wirt: | Rat |
Spezies-Reaktivität: | mouse |
289,00 €
Artikelnummer: E-AB-F1131I.200
CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral...
Schlagworte: | Anti-mPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1, PE/Cyanine5.5 Anti-Mouse CD279/PD-1... |
Anwendung: | FC, FC (membrane) |
Wirt: | Rat |
Spezies-Reaktivität: | mouse |
168,00 €
Artikelnummer: E-AB-F1129A.100
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on...
Schlagworte: | Anti-hPD-1, Anti-CD279, Anti-Protein PD-1, Anti-Programmed cell death protein 1, Purified Anti-Human CD279/PD-1... |
Anwendung: | FC, FC (membrane) |
Wirt: | Mouse |
Spezies-Reaktivität: | human |
ab 28,00 €