Zu "K06708" wurden 137 Artikel gefunden!
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PD-L2 Fc Chimera, Human
Artikelnummer: GSC-Z03417-1
PD-L1 and PD-L2 are ligands for PD-1, a costimulatory molecule that plays an inhibitory role in regulating T cell activation in the periphery. PD-L2 also known as PD-L2, B7-DC serves as a negative and a positive regulator of T cell function. The expression and function of PD-L2 are similar to PD-L1. Both PD-L2-PD-1...
| Schlagworte: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Ursprungsart: | human |
ab 336,00 €
PD-L2/B7-DC hFc Chimera, Human
Artikelnummer: GSC-Z05745-100
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong...
| Schlagworte: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Ursprungsart: | human |
| MW: | 48.6 kD |
ab 403,00 €
CHO-K1/PD-L2 Stable Cell Line
Artikelnummer: GSC-M00627
Recombinant CHO-K1 cells stably overexpress human programmed cell death 1 ligand 2 (PD-L2) on the surface. The surface expression of PD-L2 is validated by FACS analysis. This cell line is recommended for cell-based binding assay to screen antibodies against PD-L2 or to measure binding affinity between PD-L2 and...
| Schlagworte: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
11.424,00 €
![PD-L2/B7-DC[Biotin], His & Avi, Human](https://www.biomol.com/media/image/7d/5f/b9/GSC-Z04586-100_200x200.png "PD-L2/B7-DC[Biotin], His & Avi, Human")
PD-L2/B7-DC[Biotin], His & Avi, Human
Artikelnummer: GSC-Z04586-100
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong...
| Schlagworte: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Ursprungsart: | human |
| MW: | 25.3 kD |
ab 887,00 €
PD-L2/B7-DC, His & Avi, Human
Artikelnummer: GSC-Z05746-100
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong...
| Schlagworte: | PDCD1LG2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Ursprungsart: | human |
| MW: | 25.3 kD |
ab 349,00 €
PD-L2/B7-DC, His, Mouse
Artikelnummer: GSC-Z06303-100
PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong...
| Schlagworte: | Pdcd1lg2, Butyrophilin B7-DC, Programmed cell death 1 ligand 2 |
| Ursprungsart: | mouse |
| MW: | 23.92 kD |
ab 403,00 €
TCR Activator / PD-L2 Mammalian Expression Kit
Artikelnummer: BPS-60620
The recombinant expression vectors are designed to express human engineered T cell receptor (TCR) activator and human PD-L2 (GenBank Accession #NM_025239) in mammalian cells. The transfected cells can be used in conjunction with PD-1/NFAT Reporter/Jurkat T cells (BPS #60535) to study the interactions of PD-1 with...
| Schlagworte: | Programmed Cell Death 2 Ligand 2, PDL2, PD-L2, CD273, PDCDL1G2, B7-DC, |
| Anwendung: | Activator / inhibitor screening, ligand interaction studies |
| Spezies-Reaktivität: | human |
894,00 €
PD-L2 (CD273), Fc fusion (Human) HiP(TM)
Artikelnummer: BPS-71107
Human secreted Programmed Death Ligand 2 (PDL2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, expressed in a HEK293 cell expression system. MW = 49. Protein function: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG...
| Schlagworte: | B7DC, PD-L2, CD273, B7-DC, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 49 kD |
498,00 €
PD-L2 (CD273), human recombinant protein, C-terminal Avi-tag
Artikelnummer: BPS-71108
Human secreted Programmed Death Ligand 2 (PDL2)-Fc fusion protein, also known as CD273, PDCDL1G2, and B7-DC, GenBank Accession No. NM_025239, a.a. 20-219, with C-terminal Avi-tag, expressed in a HEK293 cell expression system. MW = 51. Protein function: Involved in the costimulatory signal, essential for T- cell...
| Schlagworte: | B7DC, PD-L2, CD273, B7-DC, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | Binding assays, inhibitor screening, selectivity profiling |
| Exprimiert in: | Human cells |
| Ursprungsart: | human |
| MW: | 51 kD |
663,00 €
![PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit](https://www.biomol.com/media/image/f2/f2/f8/BPS-72004_200x200.png "PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit")
PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit
Artikelnummer: BPS-72004
Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-1:PD-L2[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 96-well...
| Schlagworte: | B7DC, PD-L2, B7-DC, CD273, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | PD-1:PD-L2[Biotinylated] Inhibitor Screening |
1.664,00 €
PD-L2 Inhibitor Screening Assay Kit
Artikelnummer: BPS-72006
Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. The PD-L2 Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling. This kit comes in a convenient 96-well format, with...
| Schlagworte: | B7DC, PD-L2, B7-DC, CD273, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | PD-L1 Inhibitor Screening |
1.875,00 €
PD-1:PD-L2 TR-FRET Assay Kit
Artikelnummer: BPS-72012
The PD-1:PD-L2 TR-FRET Assay Kit is designed to measure the inhibition of PD-1 binding to PD-L2 in a homogeneous 384 reaction format. Cell signaling through the PD-1 receptor upon binding the PD-L2 ligand attenuates immune responses and is exploited by both tumors and viruses. This FRET-based assay requires no...
| Schlagworte: | B7DC, PD-L2, CD273, B7-DC, PDCD1LG2, PD-1 ligand 2, PDCD1 ligand 2, Butyrophilin B7-DC, Programmed death ligand 2,... |
| Anwendung: | Small molecular inhibitor screening, drug discovery, HTS |
| Spezies-Reaktivität: | human |
1.628,00 €