Zu "K06642" wurden 95 Artikel gefunden!
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Anti-PRKDC
Artikelnummer: ABS-KC-6291.100
Protein function: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (PubMed:11955432, PubMed:12649176, PubMed:14734805). Must be bound to DNA to express its catalytic...
| Schlagworte: | Anti-DNA-dependent protein kinase catalytic subunit, Anti-DNA-PK catalytic subunit, Anti-DNA-PKcs, Anti-DNPK1, Anti-p460,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
Anti-PRKDC
Artikelnummer: ABS-KC-6292.100
Protein function: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination (PubMed:11955432, PubMed:12649176, PubMed:14734805). Must be bound to DNA to express its catalytic...
| Schlagworte: | Anti-DNA-dependent protein kinase catalytic subunit, Anti-DNA-PK catalytic subunit, Anti-DNA-PKcs, Anti-DNPK1, Anti-p460,... |
| Wirt: | Mouse |
| Spezies-Reaktivität: | human |
ab 232,00 €
VX-984
Artikelnummer: Cay42072-1
VX-984 is an inhibitor of DNA protein kinase (DNA-PK). It inhibits radiation-induced increases in phosphorylated DNA-PK levels in U251 and NSC11 glioblastoma cells when used at concentrations of 250 or 500 nM. VX-984 (1 µM) induces mutagenic NHEJ and homologous recombination DNA repair pathways in a reporter assay...
| Schlagworte: | M-9831, N-methyl-8-[(1S)-1-methyl-2-[(2'-methyl[4,5'-bipyrimidin]-6-yl-4',6'-d2)amino]ethyl]-4-quinolinecarboxamide |
| Anwendung: | DNA-PK inhibitor |
| CAS | 1476074-39-1 |
| MW: | 415.5 D |
ab 108,00 €
NU 7026
Artikelnummer: Cay13308-5
DNA-dependent protein kinase (DNA-PK) binds to strand breaks produced during normal cellular processes or in response to genotoxic stresses, such as ionizing radiation, targeting substrates that facilitate DNA repair. NU 7026 is a cell-permeable, potent, specific, and ATP-competitive inhibitor of DNA-PK (IC50 = 230...
| Schlagworte: | DNA-PK Inhibitor II, LY293646, 2-(4-morpholinyl)-4H-naphtho[1,2-b]pyran-4-one |
| Anwendung: | DNA-PK inhibitor |
| CAS | 154447-35-5 |
| MW: | 281.3 D |
ab 111,00 €
DNA-PKcs Protein, Dictyostelium discoideum, Recombinant...
Artikelnummer: TGM-TMPH-00476-100ug
Description: DNA-PKcs Protein, Dictyostelium discoideum, Recombinant (His & Myc) is expressed in E. coli.
| Schlagworte: | DNA-PKcs, DNA-dependent protein kinase catalytic subunit, dnapkcs, DNA-PK catalytic subunit |
| MW: | 46.1 kD |
ab 359,00 €
KU-0060648
Artikelnummer: TGM-T6557-100mg
Description: KU-0060648 is a dual inhibitor of DNA-PK and PI3Kalpha, PI3Kbeta, PI3Kdelta with IC50 values of 8.6 nM, 4 nM, 0.5 nM, and 0.1 nM respectively, and demonstrates less inhibition of PI3Kgamma with an IC50 of 0.59 µM. Target: mTOR, PI3K, DNA-PK. Smiles:...
| Schlagworte: | KU0060648 |
| Anwendung: | Dual PI3K & DNA-PK inhibitor |
| CAS | 881375-00-4 |
| MW: | 582.71 D |
ab 55,00 €
LTURM34
Artikelnummer: TGM-T15789-100mg
Description: LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K . Target: PI4K, PI3K, DNA-PK. Smiles: O=c1nc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1. References:...
| Anwendung: | DNA-PK inhibitor |
| CAS | 1879887-96-3 |
| MW: | 414.48 D |
ab 40,00 €
CC-115
Artikelnummer: TGM-T3541-100mg
Description: CC-115 is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). Target: DNA-PK, PI3K, mTOR. Smiles: CCN1C(=O)CNc2ncc(nc12)-c1ccc(nc1C)-c1ncn[nH]1. References: Thijssen R, et al. Blood. 2016, 128(4):574-83.
| Schlagworte: | CC 115 |
| Anwendung: | DNA-PK / mTOR inhibitor |
| CAS | 1228013-15-7 |
| MW: | 336.35 D |
ab 40,00 €
KU-57788
Artikelnummer: TGM-T6276-100mg
Description: NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM). Target: CRISPR/Cas9, DNA-PK. Smiles: O=c1cc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1. References: Sunada S, et al. Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with...
| Schlagworte: | NU7441 |
| Anwendung: | DNA-PK inhibitor |
| CAS | 503468-95-9 |
| MW: | 413.49 D |
ab 34,00 €
AZD-7648
Artikelnummer: TGM-T7122-100mg
Description: AZD-7648 is an inhibitor of DNA-dependent protein kinase (DNA-PK) with the IC50 of 0.63 nM in an enzyme assay,has anti-tumor activity. Target: DNA-PK. Smiles: Cc1cc2ncnn2cc1Nc1ncc2n(C)c(=O)n(C3CCOCC3)c2n1. References: Maurice Raymond Verschoyle Finlay, et al. Amino-triazolopyridine compounds and their...
| Anwendung: | DNA-PK inhibitor |
| CAS | 2230820-11-6 |
| MW: | 380.4 D |
ab 34,00 €
Anti-PRKDC
Artikelnummer: CSB-PA002177.100
Host Species: Rabbit. Isotype: IgG. Buffer: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific...
| Schlagworte: | Anti-p460, Anti-HYRC, Anti-DNPK1, Anti-PRKDC, Anti-DNA-PKcs, Anti-DNA-PK catalytic subunit, Anti-DNA-dependent protein... |
| Anwendung: | ELISA, WB, IHC, IF |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human, mouse |
ab 126,00 €
Anti-PRKDC (Ab-2609)
Artikelnummer: CSB-PA178115.100
Host Species: Rabbit. Isotype: IgG. Buffer: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Storage: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Purification Method: Antibodies were produced by immunizing rabbits...
| Schlagworte: | Anti-p460, Anti-HYRC, Anti-DNPK1, Anti-PRKDC, Anti-DNA-PKcs, Anti-DNA-PK catalytic subunit, Anti-DNA-dependent protein... |
| Anwendung: | ELISA, WB |
| Wirt: | Rabbit |
| Spezies-Reaktivität: | human |
283,00 €